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Automated Cryogenic Skin Treatment

a skin treatment and cryogenic technology, applied in the field of skin treatment technologies, can solve the problems of hyperpigmentation, radiation treatment can be painful for patients, treatment is not precisely targeted to only treat hair follicles, etc., and achieve the effect of reducing the number of pulses

Inactive Publication Date: 2010-04-08
VANDOLAY INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0017]As used herein, the term “lesion” means an area of abnormal tissue including, for example, age spots such as from a buildup of lipofuscin, warts, melasmi, lentigines, melanin, and other abnormal pigmentations or growths. As used herein, the term “cryogenic fluid” includes any commercially suitable fluid for contact with skin that can be cooled to a temperature below −5° C. including, for example, water, air, carbon dioxide, nitrogen, difluoroethane, dichloro difluoro methane, tetrafluoroethane, either alone or in combination. As used herein, the term “fluid” includes for example, liquids, gases, and some solids such as fluidized cryogenic pellets. As used herein, the term “pulse” includes spurts, sprays, pellets, or other fluid ejecta emitted in a short amount of time.
[0018]When the valve is opened, the cryogenic fluid flows from a cartridge to the nozzle, which directs the cryogenic fluid to a target region of the skin. All commercially suitable nozzle configurations are contemplated including, for example, straight through designs, converging designs, diverging designs, and coherent stream designs, either alone or in combination. Although preferred nozzles have a single entrance and exit, multiple entrances or exits are also contemplated (e.g., 3-way nozzles). The nozzle can advantageously create a coherent (e.g., collimated) stream or spray such that treatment of multiple regions of the lesion is consistent. However, it is also contemplated that non-coherent streams (e.g., divergent) could be used and controlled by adjusting the distance between the skin and the nozzle.
[0025]The boundaries of the lesions can be tagged for possible treatment, and a course of treatment can be determined. Imaging can be performed at multiple wavelengths to enhance contrast and improve detection. Alternatively, white light illumination can be combined with a color imaging sensor to measure absorption and scattering at specific wavelengths.
[0030]In one embodiment, the course of treatment produces a pixelated pattern having a greater density of pulses near the center of the lesion likely from a larger number of overlapping regions. As the distance of each region's center from the lesion's center increases, the density of pulses will decrease. Alternatively, it is contemplated that one or more nozzles can utilize a mask or other pulse distribution that allows the distribution of the cryogenic fluid in each pulse to be greater near the center of the lesion. Such distribution can also be accomplished by using variable duration pulses or multiple nozzles, such as to create concentric distributions of cryogenic fluid on the lesion and thereby weight the distribution of fluid toward the center of the lesion.
[0031]Preferably, the pulses are separated by no more than 30 seconds, though it is especially preferred that the pulses are separated by no more than 20 or even less than 10 seconds. It is contemplated that the first and second pulses could be separated by as little as 10 milliseconds. The time between each pulse can be adjusted according to the distance between the centers of the region and the properties of the cryogenic fluid. Thus, for example, regions that overlap may require a longer period between pulses than regions that do not overlap. By minimizing the duration of the pulses, any pain or discoloration (e.g., hyper- or hypo-pigmentation) of the skin can be limited.
[0038]The machine can preferably at least partially differentiate among at least two of a lentigo, a skin tag, a mole, a wart, a keratosis, acne, leukoplakia, or other lesion. This is advantageous as such a machine would be able to accurately diagnose what lesion or lesions are present on a patient's skin, ensuring a proper course of treatment is applied.

Problems solved by technology

However, such treatments typically are slow, result in subtle improvement of the skin, may cause hypo- or hyper-pigmentation, and are often insufficient.
Such device treatments initially damage the target area, such that new skin proliferates after the healing process and generally improves the skin's appearance.
However, such radiation treatment can be painful for patients.
In addition, such treatment is not precisely targeted to only treat the hair follicles.
However, such methods are problematic as they use the pulses to dig or pit into the skin, rather than attempt to dither (feather) the discoloration resulting from the treatments.
In addition, such methods can leave scars on a patient.
The above laser treatments all suffer from similar disadvantages.
Laser treatments often cause patients unnecessary pain or can scar the patient's skin.
During laser treatment, scattering and absorption of the laser light often occurs in the skin tissue, which can cause significant changes in skin coloration and even scarring.
In addition, laser treatments are often manually mediated, which can lead to mismatch of the flux of the laser to the spot.
In addition, such manual mediation often leads to wide variation of treatment from one practitioner to the next.
However, such IPL devices suffer from many of the disadvantages discussed above.
Cooling the region to too low a temperature can cause excessive damage.
Cooling the region for too long a period of time can cause conduction of the cold temperature to neighboring tissue, increasing the size of the affected area.
In addition, while surrounding tissue can survive a brief exposure to the very cold temperatures, prolonged exposure can cause tissue necrosis or excessive damage.
The Weber device can be problematic as it simply sprays a cryogenic mist over the entire treatment area, which can lead to excessive or insufficient treating and cause hyper- or hypo-pigmentation of the skin.
In addition, the Weber device requires manual movement and therefore lacks the ability to be positioned precisely over the desired treatment area, making it difficult to precisely control the temperature of the treatment area and surrounding skin, which often leads to inconsistent treatment.
However, the Zavislan device also utilizes a single pulse of cryogenic fluid to flood the entire treatment area, and suffers from the same problems as the Weber device discussed above.

Method used

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Examples

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Embodiment Construction

[0046]The following description discusses inventive concepts with respect to treating a patient's right or left hand. One should appreciate that the techniques can be equally applied to other areas of a patient's skin. In addition, the techniques described herein could be applied to animals, plants and so forth.

[0047]Overview

[0048]The apparatus discussed herein utilize one or more cryogenic fluids to treat a lesion on a patient's skin. Though preferred cryogenic fluids are cold at standard pressure, it is also contemplated that the cryogenic fluid could alternatively be cooled or heated as needed prior to being dispensed through the nozzle. Additionally, or alternatively, the cryogenic fluids could be cooled through expansion after exiting a nozzle, as is consistent with reduction of pressure of a gas. In some embodiments the fluid can be recaptured or recycled.

[0049]The rate at which the pressure of the fluid impinging on the skin rises can be controlled by appropriate pulsing of a...

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PUM

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Abstract

An apparatus and methods for treating lesions on skin are presented. The apparatus collects information about a lesion and can automatically determine a course of treatment for the lesion. The device can include a controller that positions the nozzle proximate to a surface region of the lesion and automatically dispenses a pulse of the cryogenic fluid from the nozzle. The controller then positions the nozzle proximate to another surface region of the lesion and automatically dispenses a pulse of the cryogenic fluid from the nozzle.

Description

[0001]This application claims the benefit of priority to U.S. Provisional Application having Ser. No. 61 / 103,285 filed on Oct. 7, 2008. This and all other extrinsic materials discussed herein are incorporated by reference in their entirety. Where a definition or use of a term in an incorporated reference is inconsistent or contrary to the definition of that term provided herein, the definition of that term provided herein applies and the definition of that term in the reference does not apply.FIELD OF THE INVENTION[0002]The field of the invention skin treatment technologies.BACKGROUND[0003]Many people seek skin treatment to improve the appearance of their skin, and particularly to reduce the discernible appearance of discolorations generally associated with aging. The skin conditions often targeted by such treatments include skin tags, moles, freckles, warts, actinic or seborrheic keratoses, angiomas and age spots (also known as liver spots), lentigines, or other skin-related abnorm...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B18/02
CPCA61B18/0218A61B2017/00747A61B2017/00084A61B19/5212A61B90/361
Inventor DA SILVA, LUIZCOHEN, DONALDLIEBERMAN, MARC
Owner VANDOLAY INC
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