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Losartan potassium and hydrochrothiazide dropping pills and their preparing methods

A technology of losartan potassium hydrochlorothiazide and losartan potassium, which is applied in the field of losartan potassium hydrochlorothiazide dropping pills, can solve the problems of low bioavailability, long disintegration time, influence on drug efficacy and the like, and achieves high bioavailability, high Good drug stability and fast onset effect

Inactive Publication Date: 2007-06-20
陈茜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the characteristics of the preparation technology and dosage forms of these conventional preparations, such oral preparations have disadvantages such as long disintegration time, slow onset of action, and low bioavailability, which affect the full play of the drug effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0029] Embodiment: every 1000 losartan potassium hydrochlorothiazide dropping pills ratio of raw and auxiliary materials

[0030] Example

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PUM

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Abstract

A dripping pill of losartan potassium and hydrochrothiazide for treating hypertension and heart failure is prepared from losartan potassium, hydrochrothiazide and matrix. Its preparing process is also disclosed.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a losartan potassium hydrochlorothiazide drop pill prepared from chemical raw materials losartan potassium (Losartan Potassium), hydrochlorothiazide (Hydrochrothiazide) and a drop pill base. Background technique [0002] Hypertension is one of the most common cardiovascular diseases in the world today and the leading cause of death and disability in adults. Due to the improvement of people's living standards and the increasingly tense job competition, the number of people suffering from high blood pressure has increased significantly. The prevalence of hypertension in my country has increased significantly. According to statistics in China, the incidence of hypertension among people aged 35 to 74 in China is as high as 27%, and the number of patients is close to 130 million. , and with an annual growth rate of more than 300 million people, my country has become the c...

Claims

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Application Information

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IPC IPC(8): A61K31/549A61K31/4178A61K9/20A61P9/12
Inventor 陈茜滕慧丽
Owner 陈茜
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