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Medicament for treating coronary heart disease and senile deficiency syndrome and preparation process thereof

A technology for frailty and coronary heart disease, applied to the soft capsule preparation of the drug and its preparation field, can solve the problems of inability to achieve good results in the treatment of Qi deficiency syndrome, insufficient Qi replenishment, etc., and achieve rapid onset, complete efficacy, and improved stability sexual effect

Inactive Publication Date: 2007-05-23
CHENGZHENG XINKAI PHARMA FACTORY SUZHOU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Shengmaisan has the effects of strengthening the heart and improving peripheral blood circulation in the treatment of coronary heart disease, but it is insufficient in replenishing qi and cannot achieve the good effect of treating qi deficiency.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Astragalus 800g Ophiopogon japonicus 400g Schisandra 250g Codonopsis 500g.

[0039] According to the above weight ratio, the astragalus is decocted twice with water, the first time is 2 hours, the second time is 1 hour, the decoction liquid is combined, filtered, the filtrate is concentrated, let it cool, and ethanol is added to make the alcohol content 50%. Stand for 20 hours, filter, precipitate and dry to obtain crude polysaccharides of astragalus; add Codonopsis radix, Ophiopogon japonicus and Schisandra chinensis together with water and decoct once, the first time is 2 hours, the second time is 30 minutes, filter, and the filtrates are combined and concentrated under reduced pressure to a specific gravity of 1.15~ 1.20 (50° C.), use three times the amount of 95% ethanol to ethanol precipitate, concentrate the supernatant, then mix with Astragalus crude polysaccharides to obtain the extract of the present invention, and make preparations according to conventional tec...

Embodiment 2

[0041] Astragalus 500g, Ophiopogon japonicus 600g, Schisandra 300g, Codonopsis 600g.

[0042] According to the above weight ratio, the astragalus is decocted twice with water, the first time is 2 hours, the second time is 1.5 hours, the decoction liquid is combined, filtered, the filtrate is concentrated, let it cool, and ethanol is added to make the alcohol content 70%. Stand for 30 hours, filter, precipitate and dry to obtain crude polysaccharides of astragalus; add Codonopsis radix, Ophiopogon japonicus and Schisandra chinensis together with water and decoct 3 times, the first time is 1 hour, the second time is 60 minutes, filter, and the filtrates are combined and concentrated under reduced pressure to a specific gravity of 1.15~ 1.20 (50° C.), use three times the amount of 95% ethanol to ethanol precipitate, concentrate the supernatant, then mix with Astragalus crude polysaccharides to obtain the extract of the present invention, and make preparations according to conventi...

Embodiment 3

[0044] Astragalus 750g Ophiopogon japonicus 500g Schisandra 250g Codonopsis 500g.

[0045] According to the above weight ratio, the astragalus is decocted twice with water, the first time is 2 hours, the second time is 1.5 hours, the decoction liquid is combined, filtered, the filtrate is concentrated, let it cool, and ethanol is added to make the alcohol content 60%. Leave it for 24 hours, filter, precipitate and dry to obtain crude polysaccharides of astragalus; add Codonopsis radix, Ophiopogon japonicus and Schisandra chinensis together with water and decoct twice, the first time for 1 hour, the second time for 45 minutes, filter, and the filtrates are combined and concentrated under reduced pressure to a specific gravity of 1.15~ 1.20 (50° C.), with three times the amount of 95% ethanol alcohol precipitation, the supernatant is concentrated, and then mixed with Astragalus crude polysaccharide to obtain the extract of the present invention, which will be formulated according...

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PUM

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Abstract

The invention discloses a medicinal prescription for treating coronary disease and senility asthenia, wherein the medicament is prepared from the following raw materials (by weight portion): astragalus root 50-100, ophiopogon root 30-60, schisandra fruit 10-30, root of pilose asiabell 30-60. The preparing process comprises the following steps: (1) grilling astragalus root twice, merging the grilling liquids, filtering, concentrating the filtrate, cooling down, charging ethanol, precipitating, filtering, depositing and drying to obtain crude astragalus root polysaccharides, (2) boiling codonopsis pilosula, ophiopogon root and schisandra fruit with water, filtering, decompression concentrating the filtrate, depositing with 3 times of ethanol, concentrating the supernatant fluid, blending with crude astragalus root polysaccharides.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a medicine and a preparation method thereof for treating deficiency of both qi and yin, coronary heart disease with palpitation and shortness of breath, and senile weakness, as well as a soft capsule preparation of the medicine and a preparation method thereof. Background technique [0002] Heart disease is one of the diseases that threaten the health of middle-aged and elderly people in contemporary times, and it is currently the leading cause of death in middle-aged and elderly people. Therefore, the prevention and treatment of coronary heart disease and the reduction of its incidence have attracted the attention of all walks of life in the world. Western medicine believes that coronary heart disease is caused by insufficient myocardial blood supply in the supply area due to coronary artery spasm and other reasons. Therefore, Western medicine treatmen...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P9/10A61P1/14
Inventor 刘志祥米靖宇阎政王金陵杨南林
Owner CHENGZHENG XINKAI PHARMA FACTORY SUZHOU
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