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Traditional Chinese medicinal compound preparation for treating asthma and its preparation method

A compound preparation and asthma technology, applied in the field of traditional Chinese medicine compound preparations, can solve the problems of patients who cannot effectively prevent recurrence, the effect is not satisfactory, and only pay attention to asthma, so as to improve the dynamic compliance of the lungs, eliminate water and dampness, stop gathering and form phlegm , the effect of reducing airway inflammation

Inactive Publication Date: 2007-05-02
BEIJING QI YUAN YI DE PHARMA RESEARCH CENTER
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern medicine believes that asthma is a chronic airway inflammation involving eosinophils, mast cells, T lymphocytes and other inflammatory cells. Therefore, Western medicine treatment mainly focuses on anti-inflammatory and antispasmodic agents. The market mainly uses corticosteroid inhalants. , adrenaline inhalers, other asthma inhalants, systemic epinephrine and other Western medicines are dominant. Although these drugs have a relatively rapid effect and are easy to relieve symptoms in patients with acute attacks, they "only treat the symptoms, not the root cause". Only pay attention to asthma relief, but chronic eosinophilic bronchial inflammation, which is the root cause of asthma recurrence, has not been eliminated. As long as an allergen is encountered at any time, asthma will definitely be induced, and the relapse cannot be effectively prevented for patients in the remission period, so the effect is not ideal and there is a certain risk. side effects of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] Example 1: 1 part of Morinda officinalis, 1 part of Huhuanglian

[0095] Take the Morinda officinalis medicinal material, add 8 times the volume of 70% ethanol to reflux and extract 3 times, each time for 1 hour, combine the extracts, recover the ethanol under reduced pressure and measure the relative density to 1.05-1.15 at 60°C, add water 4 times the volume of the medicinal material Dissolve, filter, and the filtrate passes through the polyamide column at a speed of 0.5ml / g medicinal material.min, wash impurities with water 7 times the volume of polyamide and 10% ethanol 5 times the volume of polyamide, and then use 60% alcohol 5 times the volume of polyamide Desorb with ethanol, collect the desorption liquid, recover the ethanol under reduced pressure to 60°C, measure the relative density to 1.05-1.15, dry to obtain Morinda officinalis extract I, take Morinda officinalis dregs, add 10 times the amount of water to decoct 3 times, each For 1.0 hour, combine the extract...

Embodiment 2

[0096] Embodiment 2: 99 parts of Morinda officinalis, 1 part of Huhuanglian

[0097]Take the Morinda officinalis medicinal material, add 8 times the volume of 70% ethanol to reflux and extract 3 times, each time for 2.0 hours, combine the extracts, recover the ethanol under reduced pressure and measure the relative density to 1.05-1.15 at 60°C, add water 4 times the volume of the medicinal material Dissolve, filter, and the filtrate passes through the polyamide column at a speed of 0.6ml / g medicinal material.min, wash the impurities with water 5 times the volume of polyamide and 8% ethanol 3 times the volume of polyamide, and then use 50% alcohol 5 times the volume of polyamide Desorb with ethanol, collect the desorption liquid, recover the ethanol under reduced pressure to 60°C, measure the relative density to 1.05-1.15, dry to obtain Morinda officinalis extract I, Morinda officinalis dregs, add 8 times the amount of water to decoct 3 times, each time After 2.0 hours, combine...

Embodiment 3

[0098] Embodiment 3: 1 part of Morinda officinalis, 99 parts of Huhuanglian

[0099] Take the Morinda officinalis medicinal material, add 15 times the volume of 70% ethanol to reflux and extract for 2.5 hours, and recover the ethanol from the extract under reduced pressure to 60°C, and measure the relative density as 1.05-1.15, add 5 times the volume of the medicinal material to dissolve, filter, and the filtrate is 0.8 The speed of ml / g medicinal material.min passes through the polyamide column, and the impurities are washed with water 3 times the volume of polyamide and 10% ethanol 4 times the volume of polyamide, and then desorbed with 60% ethanol 8 times the volume of polyamide, and the desorption solution is collected. Recover ethanol under reduced pressure to 60°C and measure the relative density to be 1.05-1.15, dry to obtain Morinda officinalis extract I, Morinda officinalis medicinal residue, add 8 times the amount of water to decoct 3 times, each time for 1.0 hour, co...

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Abstract

A composite medicine in the form of injection or orally taken solid or liquid for treating asthmatic chronic bronchitis, acute bronchal asthma, lung infection, pneumonia, pneumonectasis, cardiogenic asthma, pulmonary tuberculosis, silicosis, etc is prepared from indianmulberry root or its extract and picrorhiza rhizome or its extract. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating asthma, and provides a preparation method of the compound preparation, which belongs to the technical field of traditional Chinese medicine. technical background [0002] Asthma is a global, one of the most common clinical chronic diseases that are difficult to cure and prone to repeated attacks. There are about 160 million patients in the world. Survey reports from several foreign countries indicate that the prevalence of asthma in children is 0.2% to 7.4%, and the prevalence of asthma in adults is 1.1% to 9.9%. The prevalence of asthma in my country is about 0.5% to 2.0% according to local area surveys, and it has also been reported as high as 5.29%. Asthma can occur at any age and affects men and women roughly equally in adults. With the continuous improvement of the degree of industrialization, due to the aggravation of air pollution and the development of c...

Claims

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Application Information

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IPC IPC(8): A61K36/80A61K9/00A61P11/06A61P11/00A61P31/06
Inventor 于文风
Owner BEIJING QI YUAN YI DE PHARMA RESEARCH CENTER
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