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Compound medicine prepn. for treating osteoporosis, and its prepn. method

A technology for osteoporosis and compound preparations, which can be used in medical preparations containing active ingredients, bone diseases, pharmaceutical formulas, etc. Circulation, the effect of improving the biomechanical properties of bone

Inactive Publication Date: 2007-02-14
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in bone formation accelerators, fluoride has greatly limited its clinical application because of the increase in the incidence of fractures; Statins (a HMG coenzyme A reductase inhibitor) and Dentonin (DTN) are still in the research and development stage. Although growth hormone and insulin-like growth factor I can promote bone formation, whether they will cause the risk of tumor hyperplasia remains to be explored; although parathyroid hormone (PTH) is currently the most promising type of treatment for osteoporosis Drugs, but the existing PTH preparations are expensive and need to be administered by injection, which limits their long-term application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The compound preparation for treating osteoporosis, its weight ratio is:

[0041] Fanghai 6.48g, Rehmannia glutinosa 5.40g, Dipsacus 5.40g, Drynaria fortunei 3.6g, Polygonum multiflorum 2.88g, Wood beetle 2.88g, Calcined natural copper 2.88g, Angelica 2.16g, Rhizoma Chuanxiong 2.16g, Curcuma 2.16g.

Embodiment 2

[0043] It is basically the same as Example 1, but the weight ratio of the compound is: Fanghai 10g, Rehmannia glutinosa 5g, Dipsacus 5g, Drynaria fortunei 6g, Polygonum multiflorum 5g, Wood beetle 3g, Calcined natural copper 3g, Angelica sinensis 5g, Ligusticum chuanxiong 5g, Curcuma 3g.

Embodiment 3

[0045] It is basically the same as Example 1, but the weight ratio of the compound is: Fanghai 15g, Rehmannia glutinosa 8g, Dipsacus 6g, Drynaria fortunei 8g, Polygonum multiflorum 8g, Wood beetle 5g, Calcined natural copper 3g, Angelica sinensis 8g, Ligusticum chuanxiong 8g, Curcuma 4g.

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PUM

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Abstract

A Chinese medicine in the form of oral liquid, particle, capsule, tablet, or pill for treating osteoporosis is prepared from 10 Chinese-medicinal materials including prepared rehmannia root, fleece flower root, ground beetle, Chinese angelica root, etc. Its preparing process is also disclosed.

Description

1. Technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine compound preparation for treating osteoporosis and a preparation method thereof. 2. Background technology [0002] Osteoporosis is a systemic metabolic bone disease. The fine structure and integrity of bone are destroyed, bone strength decreases and fragility increases, and the risk of fracture increases. Clinically, it is diagnosed as a decrease in bone density to below 0.15 Osteoporosis criteria. Osteoporosis can be basically divided into three categories: primary osteoporosis, mainly refers to postmenopausal osteoporosis and senile osteoporosis in women; secondary osteoporosis, often secondary to other diseases such as hyperthyroidism , diabetes, Cushing's syndrome, gastrointestinal diseases, myeloma, leukemia, etc., may also be caused by side effects caused by the use of glucocorticoids, thyroid hormones, chemotherapy drugs and h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P19/08A61K35/64A61K33/34
Inventor 狄留庆吴皓陆茵李伟徐木金李莛岐张科卫陈文星李璘王爱云赵晓莉毕肖林崔小兵蔡皓倪美华
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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