Prescription of herba fibraureae recisae preparation
A technology of palmetine and preparations, which can be used in pharmaceutical formulations, antifungal agents, and resistance to vector-borne diseases, etc., and can solve problems such as toxic side effects, drug resistance, and non-reduction
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[0061] (1) Specifications, prescription and preparation method of palmatine for injection
[0062] Specification: 20mg
[0063] prescription:
[0064] Palmatine hydrochloride (calculated as palmatine hydrochloride) 20g
[0065] Mannitol 40g
[0066] Add water for injection to 2000ml
[0067] A total of 1000 bottles were made
[0068] Preparation:
[0069] Aseptic operation: Weigh mannitol according to the prescription, put it in a container, add 1600ml of water for injection, heat and stir to dissolve, then add the prescribed amount of palmitine, stir to dissolve, add an appropriate amount of 1M hydrochloric acid solution to adjust the pH value to 5.0, add Add water for injection to the full amount, add 0.05% (W / V) activated carbon, keep stirring at 40°C for 15 minutes, filter with filter paper, filter with No. 3 sand core funnel, and filter the drug solution through 0.45 μm and 0.22 μm filter membranes in a sterile room Sterilize. After measuring the content and pH val...
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