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Method for preparing Chinese herb medicine utilizing enzyme preparation

A technology of Chinese herbal medicine and enzyme preparation, which is applied in the field of preparation of Chinese herbal medicine by using enzyme preparation, which can solve the problems of large energy and manpower consumption, reduced curative effect, slow absorption, etc., and achieve the effects of reducing pharmaceutical costs, increasing extraction rate, and convenient application

Inactive Publication Date: 2007-01-10
FUZHOU ENSURE ENZYME ENG DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the backwardness of the traditional Chinese medicine production process, only a small amount of active ingredients in the medicinal materials can be extracted, resulting in a low extraction rate of active ingredients; many beneficial vitamins, trace elements, and volatile oils have been destroyed and volatilized in the high-temperature, high-pressure production process. As a result, the potency of the medicine is weakened, which affects the improvement of the efficacy of the medicine; in addition, the active ingredients generally stay in the state of macromolecules, and can only play a role outside the cells of the diseased body, and the absorption is slow, and the curative effect is correspondingly reduced; at the same time, it consumes a lot of energy and manpower. , produce "three wastes", which cause a serious waste of Chinese herbal medicine resources, and affect economic benefits and environmental protection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Stalkless Ganoderma: 1 kg.

[0013] Prepare a multi-enzyme mixture: 10 g of cellulase, 5 g of pectinase, 5 g of protease, 3 g of peptone, 3 g of glucose, 10 ml of lactic acid, 3 g of yeast extract, 5 g of red yeast rice, and 5 g of yeast, and make 200 ml with water.

[0014] Enzyme promoter added to the multi-enzyme mixture: NaCl 2g, CaCl 2 2g, KCl 2g, MgSO 4 ·7H 2 O 0.5g.

[0015] Take 1 kg of sessile Ganoderma lucidum and dry it at 50~60℃, crush it to 20 mesh, add 3 kg of purified water, adjust the PH value of 4.5~6.5 with lactic acid and soak for 8 hours, then add 2 kg of pure water to adjust the pH to 4.0~ 5.0 Add 200ml of the multi-enzyme mixture, stir well, put it in the enzymolysis tank at 37℃ for 48 hours, stir and oxygenate 3 times a day, press and filter after the end, wash the filter residue with 50-60℃ purified water twice and filter , Combine the filtrate, concentrate and dry into powder, and sterilize the package to become the finished product.

[0016] ...

Embodiment 2

[0018] Licorice: 1 kg.

[0019] Prepare a multi-enzyme mixture: 10 g of cellulase, 5 g of pectinase, 5 g of protease, 3 g of peptone, 3 g of glucose, 10 ml of lactic acid, 3 g of yeast extract, 5 g of red yeast rice, and 5 g of yeast, and make 200 ml with water.

[0020] Enzyme promoter added to the multi-enzyme mixture: NaCl 2g, CaCl 2 2g, KCl 2g, MgSO 4 ·7H 2 O 0.5g.

[0021] Take 1 kg of licorice and dry it at 50~60℃, crush it to 20 mesh, add pure water, adjust the PH value of 4.5~6.5 with lactic acid and soak for 8 hours, then add pure water until the medicinal materials are caught in the hands and form a mass. Disperse; adjust the pH to 4.0~5.0 and add 200ml of the multi-enzyme mixture, stir evenly, put it in the enzymolysis tank for 48 hours for enzymolysis and fermentation at 37℃, stir and oxygenate 3 times a day, press and filter after the end, use 50~ for the filter residue Wash with 60℃ purified water twice and filter, combine the filtrate, concentrate and dry into powde...

Embodiment 3

[0024] Astragalus: 1 kg.

[0025] Prepare a multi-enzyme mixture: 10 g of cellulase, 5 g of pectinase, 5 g of protease, 3 g of peptone, 3 g of glucose, 10 ml of lactic acid, 3 g of yeast extract, 5 g of red yeast rice, and 5 g of yeast, and make 200 ml with water.

[0026] Enzyme promoter added to the multi-enzyme mixture: NaCl 2g, CaCl 2 2g, KCl 2g, MgSO 4 ·7H 2 O 0.5g.

[0027] Take 1 kg of astragalus and dry it at 50~60℃, crush it to 20 mesh, add 3 kg of purified water, adjust the PH value of 4.5~6.5 with lactic acid and soak for 8 hours, then add pure water until the medicinal materials are caught in the hands and form a mass. Disperse immediately after opening; adjust the pH to 4.0~5.0 and add the multi-enzyme mixture, stir evenly, and ferment for 48 hours at 37℃ in the enzymolysis tank. Stir and oxygenate 3 times a day. After the end, squeeze and filter, and use 50 for the filter residue. Wash with ~60℃ purified water twice and filter, combine the filtrate, concentrate and d...

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Abstract

The present invention relates to a method for preparing Chinese herbal medicine by using enzyme preparation. It is extracted by utilizing biochemical action. It is characterized by that it utilizes catalystic reaction of enzyme and fermentation action of microorganism, according to different medicinal material composition said invention selects the multienzyme body containing pectic enzyme, alpha-diastase and proteinase as enzyme preparation and utilizes said enzyme preparation to make the Chinese herbal medicine undergo the sufficient enzymolysis and fermentation so as to obtain the invented Chinese herbal medicine product.

Description

Technical field [0001] The present invention relates to a technology for the development and utilization of enzymes in the field of biotechnology, in particular to a method for preparing Chinese herbal medicines using enzyme preparations (that is, a method for extracting effective medicinal ingredients and functional substances from Chinese medicinal materials by enzymatic hydrolysis). technical background [0002] As we all know, traditional Chinese medicine is a great treasure house of the Chinese nation. It not only has a complete and systematic medical theory, but also countless prescriptions for treating various diseases. These prescriptions include various Chinese medicines including Chinese herbal medicine. A large number of Chinese herbal medicines are derived from the roots, stems, leaves, fruits, and flowers of plants, and their effective medicinal ingredients are mainly various natural chemical substances in plants. However, 50-75% of the dry weight of plants is cellul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00C12P1/00
Inventor 林陆山汪奋生
Owner FUZHOU ENSURE ENZYME ENG DEV
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