Citric acid half-H2O calcium sulphate bone substitute, its composition and its preparation method and uses
A technology of calcium sulfate hemihydrate and lemon, applied in medical science, prosthesis, etc., can solve the problems of expensive products, calcium sulfate hemihydrate degradation speed is not close to the speed of bone growth and repair, etc., to achieve good biocompatibility, excellent Good bone conduction and biocompatibility
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Embodiment 1
[0111] Citrated calcium sulfate hemihydrate bone graft substitute material and preparation method thereof
[0112] Add 500 grams of analytically pure calcium sulfate dihydrate, add 500ml of 5‰ citric acid, put it in an autoclave, heat it to 127°C, pressurize it to 0.15Mpa, react for 7 hours, take it out immediately, put it in a blast drying oven, Dry at 130°C for 3 hours, grind, and sieve through 180 mesh to obtain citrated calcium sulfate hemihydrate bone graft substitute material.
Embodiment 2
[0114] Citrated calcium sulfate hemihydrate bone graft substitute material and preparation method thereof
[0115] Add 750 grams of analytically pure calcium sulfate dihydrate, add 500ml of 2‰ citric acid, put it in an autoclave, heat to 110°C, pressurize to 0.09Mpa, react for 4 hours, take it out immediately, dry, grind, and sieve through 140 mesh , to obtain citrated calcium sulfate hemihydrate bone graft substitute material.
Embodiment 3
[0117] Citrated calcium sulfate hemihydrate bone graft substitute material and preparation method thereof
[0118] Add 500 grams of analytically pure calcium sulfate dihydrate, add 500 ml of 10‰ citric acid, put it into an autoclave, heat to 140°C, pressurize to 0.3Mpa, react for 8 hours, take it out immediately, dry, grind, and sieve through 200 mesh , to obtain citrated calcium sulfate hemihydrate bone graft substitute material.
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