Liquid capsule for treating mammary glands hyperplasia and breast distending pain and preparation method thereof

A technology for liquid capsules and breast swelling and pain, which is applied in capsule delivery, medical preparations containing active ingredients, and pharmaceutical formulas. It can solve problems such as complex production processes, patients should not take them, and high sugar content in granules, and achieve equipment investment. little effect

Inactive Publication Date: 2006-11-22
杨文龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to overcome the disadvantages of long disintegration time of the original dosage form tablet, complex production process, high sugar content of the granule, and some patients are not sui...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Weighing: 825g of orange leaves, 825g of salvia miltiorrhiza, 55g of saponins, 550g of wangbuliuxing, 550g of toosendan, 550g of earthworm, 339.5g of corn oil, and 10.5g of beeswax, set aside.

[0014] Then carry out the traditional Chinese medicine extraction process: orange leaves, salvia miltiorrhiza, saponins, and toosendan, etc., add 8 times the amount of water and decoct twice, each time for 1 hour, filter the decoction, combine the filtrates, and concentrate to a relative density of 1.25 ~1.30 (85°C) clear ointment, let cool, and set aside; add 8 times the amount of 70% ethanol for Dilong and Wangbuliuxing to reflux and extract twice, the first time for 2 hours, the second time for 1 hour, filter and combine Add the filtrate to the clear paste, adjust the amount of ethanol to 70%, stir evenly, let it stand, recover the ethanol and concentrate to a thick paste, dry under reduced pressure at 0.05Mpa, 65°C, crush and sieve to obtain a fine powder 400g.

[0015] The...

Embodiment 2

[0021] Weigh orange leaf 825g, salvia miltiorrhiza 825g, saponin thorn 55g, blancia 550g, toosendan 550g earthworm 550g, corn oil 385g, beeswax 20g, set aside.

[0022] Then carry out the traditional Chinese medicine extraction process: orange leaves, salvia miltiorrhiza, saponins, and toosendan, etc., add 8 times the amount of water and decoct twice, each time for 1 hour, filter the decoction, combine the filtrates, and concentrate to a relative density of 1.25 ~1.30 (85°C) clear ointment, let cool, and set aside; add 8 times the amount of 70% ethanol for Dilong and Wangbuliuxing to reflux and extract twice, the first time for 2 hours, the second time for 1 hour, filter and combine Add the filtrate to the above-mentioned clear paste, adjust the amount of ethanol to 70%, stir evenly, let it stand, recover the ethanol and concentrate it to a relative density of 1.10-1.15 (60°C). It is spray-dried at 60°C to obtain a fine powder.

[0023] Then carry out the molding process:

...

Embodiment 3

[0029] 825g orange leaves, 82g salvia miltiorrhiza, 55g saponins, 550g wangbuliuxing, 550g toosendan, 550g earthworm, 339.5g soybean oil, 10.5g beeswax

[0030] Traditional Chinese medicine extraction process: orange leaves, salvia miltiorrhiza, saponins, toosendan, etc., add 8 times the amount of water to decoct twice, each time for 1 hour, filter the decoction, combine the filtrates, concentrate to a relative density of 1.25~ 1. Clear ointment at 30°C (85°C), let it cool, and set aside; add 8 times the amount of 70% ethanol to reflux extraction for Dilong and Wangbuliuxing twice, the first time for 2 hours, the second time for 1 hour, filter, and combine the filtrates , add to the above-mentioned paste, adjust the amount of ethanol to 70%, stir evenly, let it stand, recover the ethanol and concentrate to a relative density of 1.10-1.15 (60°C) clear paste, dry under reduced pressure at 0.06Mpa, 65°C , crushed, and passed through a 120-mesh sieve to obtain a fine powder; or sp...

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PUM

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Abstract

The invention discloses a Chinese medicinal capsule for treating mammary gland hyperplasia and breast pain, which is prepared from the following constituents (by weight ratio): Chinese herbs concrete powder 1 part, dispersing agent 0.50-1.25 part, suspending agent 0.01-0.05 part, the Chinese herb concrete powder is prepared from the following raw materials (by weight proportion): orange leaves 825 parts, radix salvia miltiorrhiza 825 parts, Chinese honey locust 55 parts, seed of cowherb 550 parts, toosendan fruit 550 parts, and earthworm 550 parts, the dispersing agent is selected from edible vegetable oil, polyethylene glycol or methyl glycol, the suspending agent is bee wax or glyceryl monostearate.

Description

technical field [0001] The invention relates to a liquid capsule of traditional Chinese medicine, in particular to a liquid capsule of traditional Chinese medicine which has the functions of soothing the liver and regulating qi, promoting blood circulation and removing stasis, and is used for mammary gland hyperplasia and breast distending pain caused by stagnation of liver qi and stagnation of qi and blood stasis. Preparation. Background technique [0002] The original dosage forms of the present invention include granules, tablets and the like. The disintegration time of the tablet is long, and the production process is complicated, and the sugar content of the granule is high, so some patients should not take it. Contents of the invention [0003] The purpose of the present invention is to overcome the disadvantages of long disintegration time of original dosage form tablets, complex production process, high sugar content of granules, and some patients are not suitable...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/48A61K36/00A61K36/752A61P15/14
Inventor 杨文龙
Owner 杨文龙
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