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Weibimei medicical composition for treating stomach disease and its preparation method

A composition and drug technology, applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of low extraction efficiency of volatile oil, low bioavailability of human body, and affecting drug efficacy, etc., to achieve protection of gastric mucosa, fast treatment speed, High cure rate effect

Active Publication Date: 2006-08-30
HONGMEI PHARMA CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be seen that directly crushing fennel and aloe medicinal materials into medicine in the preparation method will make the bioavailability of the human body low and affect the curative effect; for the medicinal material Acorus calamus, the active ingredient is volatile oil, and the extraction efficiency of volatile oil is very high for the method of water extraction. low, it will also affect the efficacy of the drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Grind 15g of fennel and 12.5g of calamus calamus, and extract the volatile oil by steam distillation; add 30g of aloe vera, boil and decoct twice, add 8 times the amount of water each time, decoct for 2 hours, collect the decoction, and decoct each time The liquids were combined, filtered, concentrated into a thick paste, added 6 times the amount of water at 70°C, stirred, filtered, and the filtrate was allowed to stand at 10°C for 12 hours, then filtered, the filtrate was concentrated, dried, and crushed to obtain an aloe extract; Bismuth acid 200g, heavy magnesium carbonate 400g, sodium bicarbonate 250g, licorice extract powder 250g, buckthorn bark 15g and aloe extract mix, then add volatile oil and mix together and form the pharmaceutical composition for treating stomach disease (above group Parts are used to prepare 2g / bag of granules (1000 bags), add 740g of sucrose, 50g starch and 50g dextrin, granulate, dry, sieve and granulate, pack and divide to get granules.

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Embodiment 2

[0046] Grind 30g of fennel and 30g of calamus calamus, and extract the volatile oil by steam distillation; add 15g of aloe vera to boil and decoct 3 times, add 10 times the amount of water each time, decoct for 0.5 hours, collect the decoction, and decoct each decoction Combine, filter, concentrate into a thick paste, add 6 times the amount of water at 70°C, stir, filter, leave the filtrate at 10°C for 12 hours, filter, concentrate the filtrate, dry, and pulverize to obtain the aloe extract; 150g of bismuth, 500g of heavy magnesium carbonate, 150g of sodium bicarbonate, 250g of licorice extract powder, 5g of buckthorn bark and aloe extract are mixed, then add volatile oil and mix together and form the pharmaceutical composition for treating stomach disease; use 75% Ethanol is used as a wetting agent, granulated with a 16-mesh sieve, the drying temperature is 60° C., and the time is 2 hours. After drying, the granules are sized with a 14-mesh sieve of a swing-type granulator, an...

Embodiment 3

[0049] Grind 5g of fennel and 6g of calamus calamus, and extract the volatile oil by steam distillation; add 50g of aloe vera to boil and decoct once, add 5 times the amount of water each time, decoct for 3 hours, collect the decoction, and decoct each decoction Combine, filter, concentrate into a thick paste, add 6 times the amount of water at 70°C, stir, filter, leave the filtrate at 10°C for 12 hours, filter, concentrate the filtrate, dry, and pulverize to obtain the aloe extract; 300g of bismuth, 200g of heavy magnesium carbonate, 400g of sodium bicarbonate, 100g of licorice extract powder, 35g of buckthorn bark and aloe extract are mixed, then add volatile oil and mix together and form the pharmaceutical composition for the treatment of stomach disease; 100 grams The medicinal composition for treating stomach diseases is mixed with 15 grams of starch, added with water, granulated, passed through a 20-mesh sieve for granulation, dried, added with 1 gram of magnesium stearat...

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PUM

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Abstract

A composite medicine for neutralizing gastric acid, protecting gastric mucosa, treating gastrospasm, promoting appetite, etc is prepared from the extracts of aloe and liquorice root, the volatile oil of fennel and grass-leaved sweetflag rhizome, bismuth aluminate, heavy magnesium carbonate, sodium bicarbonate and davurian buckthorn bark through mixing and adding the pharmacologically acceptable auxiliary.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and specifically relates to a gastric bismuth magnesium pharmaceutical composition and a preparation method thereof, more specifically to a bismuth aluminate, heavy magnesium carbonate, sodium bicarbonate, licorice extract powder, A pharmaceutical composition composed of buckthorn bark, fennel, aloe and calamus and a preparation method thereof. technical background [0002] Stomach disease is a common and frequently-occurring disease that seriously endangers human health. It generally refers to gastritis and gastric and duodenal ulcer disease. The initial or mild symptoms are epigastric discomfort, fullness, heartburn, retching, and nausea. A variety of reasons can cause gastric disease, such as diet, environment, genetics, drugs, bacterial and chemical damage, smoking, etc. can all be the cause of gastric disease, resulting in excessive gastric acid secretion and aggravated gastric mucosal dama...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61P1/04A61K33/10A61K33/06
Inventor 杨尚华
Owner HONGMEI PHARMA CHINA
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