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Immune effervescent tablets for drinking water and its prepn. method

A technology of effervescent tablets and excipients, which is applied in the direction of pharmaceutical formulas, medical preparations of non-active ingredients, drug delivery, etc. It can solve the problems of reducing immune effects, weakening effervescent effects, and reducing efficiency, so as to enhance immune effects and improve The effect of disintegration speed and simple preparation method

Active Publication Date: 2006-06-14
RINGPU (BAODING) BIOLOGICAL PHARMACEUTICAL CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because there is no color indication, there is often a phenomenon of missed vaccination; at the same time, because the water quality in different regions contains different levels of heavy metal ions, when animals drink water for immunization, it will affect the vaccine to varying degrees and reduce its immune effect.
The technical feature of the existing effervescent tablet is to mix the acid system and the alkali system before granulating and compressing the tablet. In the production process, some acid and alkali have reacted, so its effervescent effect is weakened and its efficiency is reduced.

Method used

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  • Immune effervescent tablets for drinking water and its prepn. method
  • Immune effervescent tablets for drinking water and its prepn. method
  • Immune effervescent tablets for drinking water and its prepn. method

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Embodiment Construction

[0026] The weight ratio of each embodiment component is shown in the table below:

[0027]

[0028] Note: EDTA is added to alkaline or acidic system to adjust the proportion of auxiliary materials and indicators appropriately, whichever can be made into granules, and the color is uniform.

[0029] Detailed preparation method:

[0030] (1) Prepare raw materials according to the composition and the proportioning dosage of the above-mentioned embodiment.

[0031] (2) Pass all reagents through 60-70 mesh sieves respectively.

[0032] (3) A: After fully mixing the components of the acid-making granules, use a 15-18 mesh sieve to granulate;

[0033] B: After fully mixing the ingredients of the alkali-making granules, use a 15-18 mesh sieve to granulate;

[0034] Dry A and B granules at 40-65°C, pass through 8-12 mesh sieves for sizing, then fully mix A and B granules and add magnesium stearate, and then press into tablets, which are drinking water immune effervescent tablets ...

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Abstract

An effervescent tablet for improving the immunizing effect of vaccine by dissolving it in drinking water contains water-soluble non-volatile weak solid acid and hydrogen carbonate salt, water-soluble solid auxiliary and color indicator and leavy metal chelating agent.

Description

technical field [0001] The invention belongs to the technical field of preparation and application of effervescent materials, in particular to a drinking water immunization effervescent tablet capable of enhancing the immune effect of vaccines and having indication function and a preparation method thereof. Background technique [0002] At present, cold boiled water or deep well water is commonly used for animal drinking water immunization in China, or with or without skimmed milk powder to dilute the vaccine. Because there is no color indication, there is often a phenomenon of missed vaccination; at the same time, because the water quality in different regions contains different levels of heavy metal ions, when animals drink water for immunization, it will affect the vaccine to varying degrees and reduce its immune effect. The technical characteristics of the existing effervescent tablets are that the acid system and the alkali system are mixed before granulation and tablet...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K9/46A61K47/04A61K47/26
Inventor 张俊平厉从志黄华赵春梅
Owner RINGPU (BAODING) BIOLOGICAL PHARMACEUTICAL CO LTD
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