Sodium ferulate glucose infusion liquid and its preparation method

Abstract

The invention relates to ferulae acid sodium glucose liquid and its producing method. It is characterized in that it is made from ferulae acid sodium (C10H9NaO4*2H2O), glucose and stabilizing agent, while the weight proportions are: ferulae acid sodium at 90-110mg, glucose at 4500-5500mg, and the stabilizing agent at 10-100mg, to be added with asepsis injection water to 100ml. The preparing method comprises: adding the glucose as said weight proportion into asepsis injection water and injection active carbon to be boiled and mixed with heat-insulation; then adding the ferulae acid sodium and stabilizing agent as said weight proportion to be mixed and dissolved; filtering and adding asepsis injection water to full content; adjusting the pH valve to 4.0-6.0; accurately filtering, charging nitrogen, sealing, and moist heat steam sterilizing at 115Deg. C for 30 minutes to attain the ferulae acid sodium glucose liquid. The invention has significant curative effect, better stability and litter bad effect, and it has simple operation, lower cost and wider drug source.

Description

technical field [0001] The invention relates to a medical transfusion, in particular to a sodium ferulate glucose transfusion and a preparation method thereof. technical background [0002] In the past century, human beings have made remarkable achievements in the fight against diseases, especially the prevention and treatment of cardiovascular diseases. According to statistics, in the past 30 years, due to the reduction of cardiovascular disease mortality, the life expectancy of Americans has been extended by 5 years. However, with the rapid growth of the population, the absolute number of causes of cardiovascular disease will still increase, and in developed countries, it is still the first cause of death. In 1997, the World Health Organization (WHO) announced the death statistics of various diseases in the world in 1996, showing that the number of deaths from coronary heart disease, stroke and other heart diseases reached 14 million, accounting for 28.8% of the total num...

AI Technical Summary

Problems solved by technology

[0004] Sodium ferulate injection is clinically used in a large amount, but the injection is usually prepared by the hospital itself into a large-volume injection before use, which is not only inconvenient for clinical use, but also cannot guarantee the stability of the compatibility of sodium ferulate and the injection used sex

In addition, during the dilution and preparation process, if the operation is improper or the environment is not clean, it is also easy to be contaminated, which will cause pyrogenic reactions. Such situations are not uncommon in clinical practice.