Indicator for plasma sterilization and packaging material for sterilization

Abstract

An indicator for sterilization comprising an indication chemical which is useful in plasma sterilization with the use of hydrogen peroxide; and a packaging material for sterilization which has an indication unit comprising the above indicator for sterilization and in which a substance to be subjected to a plasma sterilization treatment is packaged. The above-described indicator for sterilization contains (A) one or more compounds selected from the group consisting of adsorption indication chemicals and chelate titration / metal indication chemicals and (B) an organic metal compound and shows an irreversible color change at a high speed. Thus, it enables definite judgment whether or not a subject has been plasma sterilized and, therefore, is useful as an indicator for plasma sterilization. By further adding (C) a polyhydric alcohol to the indicator, the color change speed can be elevated and well controlled, thereby giving favorable indication performance. The above-described packaging material for sterilization is a packaging material which has a part made of a gas-permeable paper or nonwoven fabric and in which a substance to be subjected to a plasma sterilization treatment is packaged. Since the above-described indicator for sterilization is employed in the indication unit of this packaging material, it can be definitely judged whether or not a subject has been plasma sterilized without affecting the sterilization performance.

Description

technical field [0001] The present invention relates to an indicator for disinfection comprising a chemical indicator, which is advantageously used in a hydrogen peroxide plasma disinfection treatment, and a packaging material for disinfection having a display comprising the indicator for disinfection as described above part, and used to store the treated objects for plasma disinfection treatment. Background technique [0002] Various disinfection methods can be used for disposable or reusable medical devices and food containers, and representative methods include ethylene oxide gas (EOG) disinfection, high-pressure high-temperature steam in an autoclave, etc. Disinfection, or plasma disinfection, etc. For example, as a disinfection method carried out in a hospital, etc., it is to put the sterilized objects such as scalpels and syringes into a packaging bag, which has at least a region that is permeable to gas but impermeable to bacteria, sealed, and then used as described ...

AI Technical Summary

Problems solved by technology

[0006] Although these display components contain pigments that are decolorized or discolored by the oxidation of gases with strong oxidizing power for plasma disinfection, the discoloration speed is slow, sufficient discoloration cannot be obtained by short-term plasma disinfection treatment, and light resistance is insufficient. , with the operation under white light or night light, it will cause problems such as undesired discoloration, so it is not ideal for application

[0007] Therefore, as an indicator with a fast discoloration rate, a pH indicator whose color changes with pH has been studied, but since the discoloration reaction is reversible, the sterilized bag having such a display part will change color even after sterilization. Changes with the storage environment, so there are problems such as whether it has been disinfected or not, and it lacks stability.