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Use of medicine in preparing medicine for treating anti-aspirin

An aspirin and medicine technology, which is applied to the application field of medicines in the preparation of medicines for treating aspirin resistance, and can solve problems such as heartache, palpitations, chest tightness, fatigue and mild symptoms.

Inactive Publication Date: 2006-01-04
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the researches on the preparations made from Sanqi, Huixincao, Erigeron, Purple Salvia, Radix Polygoni Multiflori, Corydalis Corydalis, Magnesium Stearate, Hydroxypropyl Cellulose, Polysorbate-starch, Liquid Paraffin-starch etc. mainly Concentrate on the research of heartache, palpitations, chest tightness, fatigue and mild coronary heart disease, chest tightness and angina pectoris caused by chest obstruction. There is no report about the effect of this preparation on aspirin resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1: the preparation method of Danshen Yixin Capsule

[0047] 1. Take 1250g of Panax notoginseng, 417g of Herba huixincao, 750g of escutellaria lanceolata, 550g of purple salvia miltiorrhiza, 500g of Radix Polygoni Multiflori, 417g of Corydalis Corydalis, 2.5g of magnesium stearate, 20g of hydroxypropyl cellulose, polysorbate 80-starch (1 : 20) 8g, liquid paraffin-starch (1: 20) 16g for subsequent use;

[0048] 2. The above six medicinal materials, Panax notoginseng are crushed into coarse powder, extracted twice with 6 times the amount of 80% ethanol under reflux, each time for 2 hours, filtered, combined filtrate, concentrated under reduced pressure until no alcohol smell, add water to 2500ml, liquid Pass through the treated macroporous adsorption resin column, wash with water until the effluent is pale yellow and show negative reaction to the film reagent, elute with dilute ethanol, collect the eluate, concentrate under reduced pressure to recover ethanol, c...

Embodiment 2

[0049] Embodiment 2: the preparation method of Danshen Yixin Capsule

[0050] Take 600g Panax notoginseng, 200g Huixincao, 500g Erigeron breviscapus, 300g Zidanshen, 250g Radix Polygoni Multiflori, 250g Corydalis Corydalis, 1g magnesium stearate, 12g hydroxypropyl cellulose, polysorbate 80-starch (1:20) 6g, liquid paraffin-starch (1:20) 15g;

[0051] Prepare granules according to the preparation method of Example 1, pack into capsules, and obtain final product.

Embodiment 3

[0052] Embodiment 3: the preparation method of Danshen Yixin Tablet

[0053] Panax notoginseng 2000g, Herba huixincao 700g, Erigeron breviscapus 1000g, Purple salvia miltiorrhiza 300g, Polygonum multiflorum 250g, Corydalis 750g, Magnesium stearate 5g, Hydroxypropyl cellulose 30g, Polysorbate 80-starch (1:20) 12g , liquid paraffin-starch (1:20) 24g;

[0054] According to the preparation method of Example 1, it is prepared into granules, compressed into tablets, coated with sugar or enteric coating, and obtained.

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PUM

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Abstract

The present invention provides the new use of a kind of medicine composition. The medicine composition consists of notoginseng, rose rhodobryun herb, fleabane, red sage, prepared fleeceflower root, etc. Clinical test shows that the medicine composition has the property of improving aspirin resistance and may be used in treating aspirin resistance cardiac vascular diseases to raise the life quality of the aspirin resistance cardiac vascular disease patient.

Description

technical field [0001] The invention relates to the field of medicine, in particular, the invention relates to the application of a medicine in the preparation of medicine for treating aspirin resistance. Background technique [0002] Aspirin, also known as aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth study of prostaglandins, a new understanding of aspirin has emerged: in addition to traditionally used for antipyretic, analgesic, and anti-inflammatory clinically, it is also used for anti-platelet aggregation and so on. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at present, when aspiri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/70A61K9/00A61P9/10A61P43/00
Inventor 吴廼峰郭治昕李永强郑永峰李旭郑军
Owner TIANJIN TASLY PHARMA CO LTD
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