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Preparation of Chinese medicinal suppository for treating female chronic cervicitis

A technology of chronic cervicitis and traditional Chinese medicine, applied in the direction of suppository delivery, medical formula, medical preparations containing active ingredients, etc., can solve the problems of large side effects, many vaginas, and great influence on curative effect, and achieve easy portability and use, and promote healing , definite curative effect

Active Publication Date: 2005-10-12
广西壮族自治区花红药业集团股份公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although there are many methods and medicines for treating the disease at present, these methods and medicines have many deficiencies or limitations, and it is difficult to meet the growing health needs of women.
For example, the drug therapy adopted by Western medicine is mainly based on antibiotics and hormones, which have relatively large side effects and are not suitable for popularization and promotion; physical therapy mainly uses laser and carbon dioxide freezing to act on the cervical erosion surface, so as to promote the healing of the scab on the erosion surface , this therapy must be treated in a hospital, and its curative effect is greatly affected by medical conditions and the level of doctors, and there will be more vaginal exudate during treatment. Unless it is a severe patient, most patients are unwilling to accept it; There are many effective methods and drugs for chronic cervicitis, but due to the limitations of various objective conditions, these drugs also have many unsatisfactory aspects in terms of clinical efficacy and preparation level, such as: some drugs lack modern Based on pharmacology and pharmacodynamics theory, the clinical curative effect is not accurate enough; some products have low level of preparation, and the quality of drugs is not stable enough, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] prescription:

[0045] Sophora flavescens 1600g, alum (calcined) 200g, bitter almond (燀) 130g, borneol 5g

[0046] The matrix is ​​790g of mixed fatty acid glycerides and 50g of lanolin.

[0047] Preparation:

[0048] Grind Sophora flavescens into coarse powder, use 20000ml of 1% hydrochloric acid solution as solvent, soak for 24 hours, then percolate, collect 16000ml of filtrate, pass through 732 type cation exchange resin column, wash the resin column with water until the washing liquid is colorless, Neutralize with 250ml of 0.2mol / L sodium hydroxide solution, then use 1500ml of sodium hydroxide concentration to elute with 60% ethanol solution of 0.016% (weight milliliter ratio), collect eluate 1200ml, neutralize with 2% hydrochloric acid solution to neutrality, recover ethanol, and concentrate under reduced pressure to a thick paste with a specific gravity above 1.40; dry the dried alum, superfinely pulverize it into the finest powder, and sieve; boil the bitter al...

Embodiment 2

[0051] prescription:

[0052] Sophora flavescens 2000g, alum (calcined) 300g, bitter almond (燀) 180g, borneol 5g

[0053] The matrix is ​​790g of mixed fatty acid glycerides and 50g of lanolin.

[0054] The preparation method is the same as in Example 1.

[0055] The clinical total effective rate of the suppository prepared by the method of the present invention is 87%, but the vulva is irritated to a certain extent when the drug film is discharged.

Embodiment 3

[0057] prescription:

[0058] Sophora flavescens 1800g, alum (calcined) 250g, bitter almond (燀) 150g, borneol 5g

[0059] The matrix is ​​790g of mixed fatty acid glycerides and 50g of lanolin.

[0060] The preparation method is the same as in Example 1.

[0061] The clinical total effective rate of the suppository prepared by the method of the present invention is 85%, but the vulva is irritated to a certain extent when the drug film is discharged.

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PUM

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Abstract

A Chinese medicine in the form of suppository for treating chronic cervicities is prepared from flavescent sophora rhizome, baked alum, bitter apricot kernel, borneol, and the matrix which is the mixture of glyceride of fatty acid and lanolin.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine suppository for treating women's chronic cervicitis. Background technique [0002] Chronic cervicitis is the most common gynecological disease among women of childbearing age, and its incidence rate accounts for more than 50% of married women. The chronic pathological process caused by the disease is protracted and repeated, and it is difficult to cure it. Chronic cervicitis not only causes the patient to have profuse leukorrhagia, filthy smell, swollen waist and abdomen, and pain, but also may induce cervical cancer. Therefore, it seriously affects the physical and mental health and quality of life of women. [0003] Although there are many methods and medicines for treating this disease at present, these methods and medicines all have many deficiencies or limitations, and it is difficult to meet the growing health needs of women. For ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/02A61P15/00
Inventor 梁文广温力堃梁文丽张仁健
Owner 广西壮族自治区花红药业集团股份公司
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