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Fracture union-promoting medicine and its preparation

A technology for fracture healing and medicine, applied in the preparation of the medicine, in the field of medicines for promoting fracture healing, and can solve the problems of scientific formulation, simplicity, and unfavorable taking by patients.

Active Publication Date: 2005-09-14
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sanhua Jiegu Powder is composed of 18 Chinese herbal medicines such as Panax notoginseng, saffron, and dried blood. The main saffron in the prescription is a precious medicinal material, and the medicine is a powder, which is not conducive to taking by patients.
At present, there is no Chinese patent medicine with scientific and simple prescription and obvious pharmacological effects to promote fracture healing.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Example 1. A kind of medicine that promotes fracture healing, it is the medicament that is made of the raw material of following percentage by weight,

[0054] Drynaria 28% Panax notoginseng 17% Astragalus 55%.

Embodiment 2

[0055] Example 2. A preparation method of a medicine for promoting fracture healing, the steps are as follows: (1) take 500 grams of drynaria decoction pieces and 300 grams of Sanqi coarse powder, add 50% ethanol to reflux and extract 3 times, each time for 3 hours, and the extracts are combined , reclaim ethanol and concentrate to medicinal materials: medicinal liquid is 2: 1, refrigerate, stand for 24 hours, filter, add ethanol to the filtrate until the alcohol content of the solution reaches 90%, leave standstill for 24 hours, filter, reclaim ethanol from the filtrate and concentrate to medicinal materials: The medicine solution is 5:1,

[0056] Saturated with water and extracted with n-butanol for 3 times, recovered n-butanol from the extract, concentrated to a thick paste, dried in vacuo to obtain drynaria rhizome and notoginseng extract;

[0057] (2) Take 1000 grams of Astragalus decoction pieces, add 5 times the amount of water to decoct 3 times, 1 hour each time, comb...

Embodiment 3

[0060] Example 3. A kind of medicine that promotes fracture healing, it is the medicament that is made of the raw material of following percentage by weight, and the dosage form of described medicament is tablet,

[0061] Drynaria 25% Sanqi 25% Astragalus 50%.

[0062] Its preparation method is:

[0063] (1) Take drynaria decoction pieces and Panax notoginseng coarse powder according to the above ratio, add 60% ethanol to reflux extraction twice, each time for 3 hours, combine the extracts, recover the ethanol and concentrate until the ratio of medicinal materials: medicinal liquid is 1:1, refrigerate, Stand for 48 hours, filter, add ethanol to the filtrate until the alcohol content of the solution reaches 85%, let it stand for 48 hours, filter, recover the ethanol from the filtrate and concentrate until the medicinal material: medicinal solution is 2:1, add water and extract with n-butanol for 4 times, N-butanol is recovered from the extract, concentrated to a thick paste, ...

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PUM

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Abstract

Disclosed is a fracture union-promoting medicine which is prepared from (by weight ratio) drynaria 25-35%, notoginseng 15-25%, astragalus root 40-60%. The invention also discloses the process for preparing the medicament for promoting knitting.

Description

technical field [0001] The invention relates to a medicine made from Chinese herbal medicine, in particular to a medicine for promoting fracture healing; the invention also relates to a preparation method of the medicine. Background technique [0002] At present, the treatment methods for fractures are mainly surgical reduction and fixation, but no matter how advanced the surgical method is, it usually takes 3 months or longer for fractures to heal, so that the fractured people lose the ability to work or even take care of themselves for a long time ability. In addition, due to the existence of stress shielding, osteoporosis and bone atrophy are obvious in the fracture treatment with strong internal fixation, and re-fracture is prone to occur after the internal fixation is removed; fracture treatment with elastic fixation is difficult to control the movement of the bone end, which is easy to cause fracture Delayed or no healing. [0003] There are also ...

Claims

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Application Information

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IPC IPC(8): A61P19/08
Inventor 肖伟戴翔翎凌娅廖正根刘涛钟裔荣
Owner JIANGSU KANION PHARMA CO LTD
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