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Compound preparation for treating hypertension

A compound preparation and high blood pressure technology, which is applied in cardiovascular system diseases, drug combinations, etc., can solve problems such as low blood pressure and discomfort, and achieve the effects of improving compliance, less adverse reactions, and increasing tolerance

Inactive Publication Date: 2005-02-16
GUANGDONG CARDIOVASCULAR INSITITUTE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Single use of a large dose of drugs to treat high blood pressure sometimes brings some adverse reactions, such as the compensation reaction triggered by the reduction of blood pressure during monotherapy, and fatigue, dizziness, drowsiness, tinnitus, nausea, and vomiting often occur after taking the drug , epigastric discomfort, constipation, and sometimes orthostatic hypotension, muscle cramps, insomnia and other phenomena, although most of these phenomena disappear on their own during continuous medication, they will also bring a lot of inconvenience to patients

Method used

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  • Compound preparation for treating hypertension
  • Compound preparation for treating hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A compound preparation containing the following components:

[0039] Indapamide 1.25mg

[0040] Bisoprolol 1.25mg

[0041] Microcrystalline Cellulose 20mg.

[0042] This embodiment can be made into compound indapamide-bisoprolol tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

[0043] The preparation method of the compound preparation of the following examples is the same as Example 1.

Embodiment 2

[0045] A compound preparation containing the following components:

[0046] Indapamide 1.25mg

[0047] Bisoprolol 2.5mg

[0048] Pregelatinized starch 30mg.

Embodiment 3

[0050] A compound preparation containing the following components:

[0051]Indapamide 2.5mg

[0052] Bisoprolol 1.25mg

[0053] Low-substituted hydroxypropyl cellulose 10mg.

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Abstract

The invention discloses a compound preparation for curing hypertension. The invention contains ingredients with following day doses: 0.5-2.5mg of indapamide and 1.25-5mg of piaster. The pressure relief effect is excellent than one single medicine with a large dose, and it can eliminate the bad reaction caused by one single medicine, prevents the compensation reaction caused by using one single medicine to relief blood pressure, upgrades the patience of sufferer, upgrades the compliance.

Description

technical field [0001] The invention relates to a compound preparation for treating hypertension. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. In 1991, my country conducted a sample survey of 940,000 people over the age of 15. Statistics show that the prevalence of hypertension in my country has reached 11.26%, which is 25% higher than that in the 10 years from 1979 to 1980. There are more than 130 million hypertensive patients in my country. . Moreover, this upward momentum continues. Statistics also show that the treatment rate of hypertension is 17.4% in urban areas and 5.4% in rural areas; the control rate (systolic blood pressure<140mmHg and diastolic blood pressure<90mmHg after treatment) is only 2.9%. From the above statistics, it can be seen that the prevalence of hypertension in my country is constantly increasing, but the treatment rate and control rate are low, forming a h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/404A61P9/12
Inventor 林曙光余细勇郑猛
Owner GUANGDONG CARDIOVASCULAR INSITITUTE
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