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Dripping pills of 'Xiao Chaihu'

A technology of decoction dripping pills and Bupleuri, which is applied in the field of traditional Chinese medicine preparations and its preparation, can solve problems such as the reduction of active ingredients and the first-pass effect, and achieve the effects of fast dissolution, reduced dosage, and fast release

Inactive Publication Date: 2005-01-26
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to its own reasons, oral preparations are mostly absorbed in the gastrointestinal tract, which is prone to first-pass effect, which reduces the active ingredients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] a. Take Bupleurum 33.3g, Pinellia 166.7g, Scutellaria 166.7g, Codonopsis 166.7g, Jujube 166.7g, Licorice 111.1g, Ginger 88.9g;

[0075] B. get Bupleurum chinensis, add water distillation and extract 3 times, each extraction time is 3 hours, get volatile oil and water decoction, add the remaining medicinal residues and extract 2 times with water, each time 1 hour, with the decoction of starting distillation gained Combined, properly concentrated to a relative density of 1.20 at 50°C, let cool, add ethanol to precipitate until the alcohol content reaches 70%, let stand, take the supernatant, concentrate and recover ethanol to obtain a concentrated solution for use;

[0076] c. Take the method Pinellia and ginger, add 70% ethanol to percolate, and concentrate the percolation to obtain a concentrated solution, which is used for later use.

[0077] d. Take Codonopsis, jujube and licorice, add water to extract 3 times, 1 hour each time, concentrate the combined extracts to a ...

Embodiment 2

[0081] a. Take Bupleurum 33.3g, Pinellia 166.7g, Scutellaria 166.7g, Codonopsis 166.7g, Jujube 166.7g, Licorice 111.1g, Ginger 88.9g;

[0082] B. get Bupleurum chinensis, add water distillation and extract 1 time, the extraction time is 3 hours, get volatile oil and water decoction, the remaining medicinal residues are added with water to extract a time, the time is 1 hour, merges with the decoction of starting distillation gained, Appropriately concentrated to a relative density of 1.10 at 50°C, let it cool, add ethanol to precipitate until the alcohol content reaches 50%, let it stand, take the supernatant and concentrate it to recover ethanol to obtain a concentrated solution for later use;

[0083] c. Take the method Pinellia and ginger, add 50% ethanol to percolate, and concentrate the percolation to obtain a concentrated solution, which is used for later use.

[0084] d. Take Codonopsis, jujube and licorice, add water and extract for 3 times, 1 hour each time, concentrat...

Embodiment 3

[0088]a. Take Bupleurum 33.3g, Pinellia 166.7g, Scutellaria 166.7g, Codonopsis 166.7g, Jujube 166.7g, Licorice 111.1g, Ginger 88.9g;

[0089] B. get Bupleurum chinensis, add water for distillation and extraction 2 times, each extraction time is 3 hours, get volatile oil and water decoction, add water and extract the remaining medicinal residues for 2 times, each 1.5 hours, and start the water decoction obtained by distillation Combined, properly concentrated to a relative density of 1.30 at 50°C, let cool, add ethanol to precipitate until the alcohol content reaches 50%, let stand, take the supernatant, concentrate and recover ethanol to obtain a concentrated solution for use;

[0090] c. Take the method Pinellia and ginger, add 60% ethanol to percolate, and concentrate the percolation solution to obtain a concentrated solution, which is used for later use.

[0091] d. Take Codonopsis, jujube and licorice, add water and extract twice for 0.5 hours each time, concentrate the co...

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PUM

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Abstract

The invention provides a dripping pills of radix bupleuri and its preparing method, wherein the dripping pill comprises Bupleurum root, pinellia tuber, fresh ginger, pilose asiabell root, licorice root, baikal skullcap root, through the steps of extracting, adjusting pH, spray drying, mixing extracts, concentrating, and charging auxiliary materials.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof. Specifically, the invention relates to a Xiaochaihutang dripping pill, and the invention also discloses a preparation method thereof. Background technique [0002] Xiao Chaihu Decoction comes from Zhang Zhongjing's "Treatise on Febrile Diseases", consisting of Bupleurum, Scutellaria, Ginseng, Pinellia, Licorice, Ginger, and Jujube. The original book is used to treat typhoid fever and shaoyang syndrome and the symptoms caused by it: as well as disease, jaundice, etc. and shaoyang syndrome, in long-term medical practice, this prescription is widely used in liver and gallbladder, digestion, endocrine, blood, immune and other systems disease treatment. [0003] Xiaochaihu Decoction for Yang Syndrome [0004] In traditional Chinese medicine, the three yang syndromes are combined to see the treatment from Shaoyang. The ancien...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P1/00A61P1/16A61P3/06A61P5/00A61P7/00A61P35/00A61P37/02
Inventor 叶正良童玉新李清华谢卫锋高玉珍陈莉琳
Owner TIANJIN TASLY PHARMA CO LTD
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