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Pungent rhinitis pills and their preparation

A technology of rhinitis pills and Asarum, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of easy loss of aromatic ingredients, low quality standard control indicators, and few detection data, etc., and achieve the production process Improve the effect of rationality, quality and curative effect guarantee, and quality standard improvement

Inactive Publication Date: 2004-12-08
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The capsule has a large dosage and is difficult to swallow. The ten flavors in the prescription are aromatic medicinal materials. The aromatic components are easily lost during production and storage, which affects the efficacy of the medicine. At the same time, there are shortcomings such as low quality standard control indicators, few testing data, and a single dosage form.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1: The fifteen herbs are cleaned separately, impurities are removed, and they pass the inspection for later use; the above-mentioned fifteen herbs are pulverized into fine powder, mixed with appropriate amount of auxiliary materials, pelletized, dried, and obtained.

Embodiment 2

[0041]Example 2: Clean the fifteen herbs respectively, remove impurities, and pass the test for later use; take the concentrated powder of buffalo horn and grind it into fine powder for later use; take gentian, scutellaria baicalensis, and platycodon root, mix and pulverize it into fine powder for later use, and the remaining pungent catkins, angelica dahurica, Bupleurum, Chuanxiong, mint, chrysanthemum, nepeta ear, husk (stir-fried), windproof, asarum, and vitex are crushed into coarse powder, steamed and extracted, and the volatile oil and water are collected for later use; the residue is boiled and extracted Once, combine with the above water and liquid, centrifuge, concentrate the clear liquid film to a concentrated solution with a relative density of 1.08-1.10 (60°C), spray dry to make a dry cream powder for later use; add an appropriate amount of cyclodextrin to the above volatile oil to make volatile oil cyclodextrin The inclusion compound is ready for use; take the abov...

Embodiment 3

[0042] Example 3: Clean and select the fifteen medicines separately, remove impurities, and pass the test for later use; take the buffalo horn concentrated powder and grind it into a fine powder for later use; the remaining fourteen medicines are ground into coarse powder, add water and cook twice, each time for 2 hours, and collect volatile oil and water cooking liquid for later use; water cooking liquid is filtered, and the filtrate is concentrated to a relative density of 1.08-1.10 (60°C), and spray-dried to make a dry cream powder for later use; the above-mentioned volatile oil is clathrated with cyclodextrin for later use; the above-mentioned dry cream powder, water The fine powder of ox horn concentrated powder, volatile oil cyclodextrin inclusion complex and appropriate amount of auxiliary materials are mixed evenly, pelletized and dried to obtain the product.

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PUM

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Abstract

A Chinese medicine 'Xinfang Biyan pill' for treating chronic rhinitis and nasosinusitis is an improvement to existing relative medicine in the form of capsule. Its preparing process is also disclosed. Its advantages are high curative effect, high release speed and high biological utilization rate.

Description

technical field [0001] The invention relates to the technical field of manufacturing Chinese patent medicine pills, in particular to Xinfang Biyan Pills and a preparation method thereof. Background technique [0002] Pills are a traditional dosage form. Due to the rapid development of modern science and technology, the continuous upgrading of pharmaceutical machinery and equipment, the advent of new pill-making machines and the wide application of new excipients have given youthful vitality to the ancient dosage form of traditional Chinese medicine pills. It has changed people's traditional prejudice of "black, big and thick" traditional pills, and the pills produced by it have the advantages of fast drug release, high bioavailability, accurate dosage, easy to take, carry, and beautiful appearance. According to my country's relevant drug laws and regulations, changing the dosage form is a new drug research. The original dosage form of Xinfang Biyan Pi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P11/02
Inventor 毛友昌毛晓敏
Owner 毛友昌
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