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Nano composite material for intrauterine birth control device

A nano-composite material, nano-zinc technology, applied in the field of nano-composite materials for intrauterine devices

Inactive Publication Date: 2003-09-10
HUAZHONG UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, since the current active metal IUD adopts a bare copper structure, it still cannot effectively solve the following problems: (1) regulation of the release process of copper ions to avoid the occurrence of explosive release; (2) increase the content of copper ions in the solution

Method used

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  • Nano composite material for intrauterine birth control device
  • Nano composite material for intrauterine birth control device
  • Nano composite material for intrauterine birth control device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030]Copper nanoparticles are prepared by laser-induction compound evaporation method, using 99.99% block pure copper, placed in Al 2 o 3 Inside the crucible. Vacuum the evaporation chamber to 1×10 -1 Pa, then filled with argon to 1×10 3 Pa. Start the high-frequency power supply and heat the pure copper until it melts. Introducing CO 2 Laser, the laser passes through the focusing mirror, the spot diameter is φ4mm, and the laser power is 1000W. Copper nanoparticles with an average particle diameter of 30 nm are obtained, and the purity is greater than 99%. The morphology of copper nanoparticles is shown in the appendix figure 2 .

[0031] The polymer used in the composite was commercially available low-density polyethylene (LDPE).

[0032] 5wt% (percentage by weight) of the above-mentioned copper nanoparticles and LDPE composite, the process route is active nano-metal particles and polymer premixing, blending and injection molding, made of copper nanoparticles / LDPE co...

Embodiment 3

[0041] The copper nanoparticles are prepared by a laser-induction compound evaporation method, the average particle diameter is 30nm, and the purity is greater than 99%. The morphology of copper nanoparticles is shown in the appendix figure 2 .

[0042] The polymer used in the composite was commercially available low-density polyethylene (LDPE).

[0043] 0.5wt% (weight percent) of the above-mentioned copper nanoparticles and LDPE composite, the process route is active nano-metal particles and polymer premixing, blending and injection molding, made of copper nanoparticles / LDPE composite material samples.

[0044] The sample was placed in the simulated uterine cavity fluid at 37°C to test the cumulative release of copper ions, the results are shown in the attached Figure 4 .

Embodiment 4

[0046] The copper nanoparticles are prepared by a laser-induction compound evaporation method, the average particle diameter is 30nm, and the purity is greater than 99%. The morphology of copper nanoparticles is shown in the appendix figure 2 .

[0047] The polymer used in the composite was commercially available low-density polyethylene (LDPE).

[0048] 10, 30, 50wt% (percentage by weight) of the above-mentioned copper nanoparticles and LDPE are compounded, and the process route is premixing, blending and injection molding of active nano-metal particles and polymers to make copper nanoparticles / LDPE composite material samples .

[0049] The sample was placed in the simulated uterine cavity fluid at 37°C to test the cumulative release of copper ions, the results are shown in the attached Image 6 .

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Abstract

The nano composite material for intrauterine birth control device consists of nano metal particle in the content of 0.5-50 wt% and biocompatible polymer. The said nano metal particle is nano copper particle, nano copper particle, nano zinc particle and / or nano silver particle. The nano composite material of the present invention features that the controllable release of the metal ions in some regulation can avoid violent release; and that raising the content in the solution can raise the birth control effect.

Description

technical field [0001] The invention relates to a nanocomposite material containing contraceptive active substances (active metal ions), in particular to a nanocomposite material used for intrauterine contraceptives. Background technique [0002] The intrauterine device (IUD) is a contraceptive tool widely used at home and abroad. There are more than 70 million women in the world who use IUD, of which my country accounts for more than 70%. As a basic national policy of our country, family planning is related to the survival and development of the nation. Among them, women's safe birth control is an important content, which is directly related to The implementation of family planning work, so the research and development of long-acting and safe birth control devices and drugs is particularly important in our country. IUD is a contraceptive tool that acts on the local area and interferes less with the body's systemic functions. It is accepted by women willingly because of its ...

Claims

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Application Information

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IPC IPC(8): A61L31/14A61L31/16
Inventor 谢长生徐涛朱长虹胡军辉黄开金胡木林
Owner HUAZHONG UNIV OF SCI & TECH
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