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Antisenility medicine composition and its prepn

A composition and anti-aging technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as side effects, dermatitis, and inability to protect the skin, so as to improve activity, delay keratinization, The effect of reducing the level

Inactive Publication Date: 2002-12-11
李祥麟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] There are many types of skin care and beauty cosmetics currently on the market, and their effects are generally only temporary. It can also cause side effects such as dermatitis
The present inventor thinks that the cosmetic ointment, cream or emulsion etc. made with organic compounds or metal substances (monomers) as additives cannot finally protect the skin and delay skin aging, and there are more or less different degrees of disadvantages and deficiencies

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0108] 1. Preparation of crude extract

[0109]Fungus: Cordyceps militaris (also known as Cordyceps militaris) 3.78 Arthrospira 0.64. Example: Cordyceps militaris (Cordyceps militaris) 37.8g, mixed with Arthrospira 6.4g and ground, add 2 times the amount of phosphate buffer (PH7.3) and neutral protease (3000 units / g) 1.5%, put in a 35°C water bath After 30 minutes, magnetically stir for 30 minutes, freeze at -20°C, and after it freezes into ice cubes, take out and thaw in a 35°C water bath, magnetically stir for 30 minutes, and freeze again. After three cycles of this, set the thawing solution to 40°C, Centrifuge at 5000 r / min and collect the supernatant to obtain "b" solution.

[0110] Algae and Chinese herbal mixture in the ratio of Arthrospira 2.46 Chuanxiong 1.84 Lycium barbarum 1.28

example

[0111] Example: Arthrospira 24.6g, Chuanxiong 18.4g, Lycium barbarum 12.89g, a total of 55.89g. Grind finely (after passing through an 80-mesh sieve), add 560 ml of deionized water, soak for 24 hours, boil for 45 minutes, and filter the supernatant.

[0112] Add 8 times the amount of deionized water to the filter residue, boil, and filter the supernatant.

[0113] The two filtrates were combined and added with the same amount of alcohol, heated to 40°C for half an hour, left standing overnight, and the supernatant was collected by filtration.

[0114] Add 5 times the amount of water and the same amount of alcohol to the precipitate, filter, and combine the filtrates twice to obtain "crude extract" a.

[0115] Mix the crude extracts "a" and "b" to form a crude extract. The crude extract can be prepared into various dosage forms such as oral liquid, granules, capsules, tablets and the like by adding various pharmaceutically acceptable conventional auxiliaries by conventional p...

Embodiment 2

[0117] Separation and purification of the crude extract of the present invention

[0118] Cellulose chromatography purification: the crude extract was diluted twice with distilled water and applied to a DEAE52 cellulose column (3×18cm). After the cellulose column, wash the column with the same buffer to the baseline, then use 10mM, PH8.0 phosphate buffer and add 0.3N, and 0.6N NaCl to partially elute and collect. Take the elution peak of 0.3N NaCl, add solid ammonium sulfate to 80% saturation, stand at 4°C for 4 hours, centrifuge at 2500r / 15 minutes, collect the precipitate and add 10ml of water to dissolve the medium, dialyze the water, and replace the dialysate twice , and finally put 500ml, 10mm, PH7.3 phosphate buffer in the dialysis equilibration solution. The dialyzed sample solution was centrifuged at 2500 r / 15 minutes to remove the precipitate, and the supernatant was filtered through a Seohade XG75 gel column (15×85 cm). Elution with the same buffer, collected in di...

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PUM

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Abstract

An antisenility medicine composition and its preparation process are disclosed. The medicine composition is prepared with spirulina, aweto and other medicine materials. It can be used in cosmetics. In addition, one SOD extracting process is also disclosed.

Description

technical field [0001] The invention relates to an anti-aging pharmaceutical composition containing raw materials such as Arthrospira, Cordyceps militaris, Chuanxiong, Lycium barbarum and the like and a preparation method thereof. Background technique [0002] With the development of the economy, the improvement of life, and the advancement of science and technology, the average life expectancy of human beings is continuously extending, and the proportion of the elderly in the total population is increasing. It has reached about 140 million, accounting for more than 10% of the total population of the country, and has entered an aging country. [0003] Aging is an inevitable phenomenon of the physiological laws of the human body. The aging process is influenced by many factors such as the environment, diet and its own health status and living habits. Apply scientific and technological means and methods to explore the occurrence and evolution of aging, and to prevent and tre...

Claims

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Application Information

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IPC IPC(8): A61K38/44A61P43/00C12N9/02
Inventor 李祥麟黄檀溪
Owner 李祥麟
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