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Medication for treating dementia in blood vessel type, and preparation method

A technology for vascular dementia and drugs, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of insignificant effect, restricted use and promotion, slow curative effect, etc.

Inactive Publication Date: 2007-08-22
刘升胜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese medicine research on VaD at home and abroad is still being explored, but the mechanism of action of Chinese medicine therapy has not yet been revealed, coupled with the problems in the formulation and dosage of Chinese medicine, which largely limits its use and promotion
In recent years, traditional Chinese medicine has provided many achievements in the treatment of VaD, but there are defects of slow curative effect and insignificant effect. For example, Tianma Zhuozhi granule and compound ginseng rhubarb preparation only show limited curative effect, and are considered to improve cognitive symptoms Better cholinergic drugs such as donepezil, traditional Chinese medicine extracts such as galantamine, huperzine A, etc. have a total effective rate of only about 70%, while the improvement of memory impairment is less than 60%; and there are many adverse effects in clinical application. Reactions, such as nausea, vomiting, diarrhea, anorexia, insomnia, dizziness, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0096] Example 1 (upper limit example):

[0097] 9 parts of ginseng, 9 parts of Panax notoginseng, 9 parts of earthworm, 18 parts of Codonopsis pilosula, 18 parts of Polygonum multiflorum (made), 18 parts of Acanthopanax, 18 parts of hawthorn, 5 parts of Coptis chinensis, 12 parts of forsythia, 12 parts of Danshen (wine roasted) 9 parts of polygala, 9 parts of Shichangpu, 9 parts of tangerine peel, and 9 parts of patchouli.

example 2

[0098] Example 2 (lower limit example):

[0099] 3 parts of ginseng, 3 parts of Panax notoginseng, 3 parts of Dilong, 6 parts of Codonopsis, 6 parts of Polygonum multiflorum (made), 6 parts of Acanthopanax, 6 parts of Hawthorn, 2 parts of Coptis chinensis, 6 parts of Forsythia, 6 parts of Danshen (wine-roasted) 3 parts of polygala, 3 parts of Shichangpu, 3 parts of tangerine peel, 3 parts of patchouli.

example 3

[0100] Example 3 (preferred example):

[0101] 6 parts of ginseng, 6 parts of Panax notoginseng, 4.5 parts of Dilong, 9 parts of Codonopsis, 7.5 parts of Acanthopanax, 9 parts of Polygonum multiflorum (made), 7.5 parts of hawthorn, 2 parts of Coptis chinensis, 7.5 parts of forsythia, 6 parts of Salvia miltiorrhiza, patchouli 4.5 parts of incense, 4.5 parts of tangerine peel, 6 parts of polygala, and 4.5 parts of Shichangpu.

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PUM

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Abstract

A Chinese medicine for treating vascular dementia is prepared from ginseng, notoginseng and earthworm. Its preparing process is also disclosed.

Description

(1) Technical field [0001] The invention relates to a medicine for treating vascular dementia (English abbreviation VaD, hereinafter the same) and a preparation method thereof, belonging to the field of traditional Chinese medicine. (2) Background technology [0002] At present, there are three main measures for the treatment of VaD: the treatment of the cause is the preventive measure of VaD; the treatment of cerebrovascular disease is the key to the prevention of VaD; the improvement of symptoms is the currently proven effective treatment. The Chinese medicine research on VaD at home and abroad is still being explored, but the mechanism of Chinese medicine therapy has not been revealed, and the problems in the formulation and dosage of Chinese medicine limit its use and promotion to a large extent. In recent years, traditional Chinese medicine has provided many achievements in the treatment of VaD, but there are defects of slow curative effect and insignificant effect. For...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/888A61K36/752A61K36/734A61K36/718A61K36/704A61K36/69A61K36/53A61K36/344A61K36/254A61K35/64A61K36/258A61K9/14A61P25/28
Inventor 刘升胜
Owner 刘升胜
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