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Preparation method of traditional Chinese medicine powder radix stephaniae tetrandrae extract

The technology of extract and traditional Chinese medicine powder is applied in the field of preparation of traditional Chinese medicine powder Fangji extract, which can solve the problems of insufficient extraction of active components, insufficient utilization of powder Fangji, low yield of alpha tetracycline, etc., and achieves improved permeability. and pit ratio, good solubility and dispersibility, the effect of improving yield

Pending Publication Date: 2022-05-31
上海浙星新型材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Nowadays, there are many research solutions on the active ingredients in Tetrandrine, but the extraction of the active ingredients is often insufficient, especially the yield of Tetrandrine is very low, and Tetrandrine has not been fully utilized

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A preparation method of Chinese medicine powder Fangji extract, comprising the steps of:

[0035] (1) Soaking treatment:

[0036] Immerse the dried roots of Fenji Fenji in the treatment solution, then place the treatment solution in an ultrasonic environment for shaking treatment, the shaking speed is 100rpm, the shaking treatment time is 1h, the frequency of the ultrasonic wave is 30kHz, each component in the treatment solution and the corresponding weight The percentages are: 0.7% cellulase, 1% hemicellulase, 0.6% pectinase, 2% ethylenediamine, and the balance is water;

[0037] (2) Continuous flash explosion treatment:

[0038] After the soaking is completed, filter out and place in a continuous flash explosion machine for continuous flash explosion treatment. The speed of the flash explosion machine is 700rpm, and the number of flash explosion treatments is 20 times. After completion, it is taken out for subsequent use;

[0039] (3) Superfine pulverization treatme...

Embodiment 2

[0050] A preparation method of Chinese medicine powder Fangji extract, comprising the steps of:

[0051] (1) Soaking treatment:

[0052] Immerse the dried roots of Fenji Fenchi in the treatment solution, then place the treatment solution in an ultrasonic environment for shaking treatment, the shaking speed is 110rpm, the time of shaking treatment is 1.5h, the frequency of the ultrasonic wave is 40kHz, the components in the treatment solution and the corresponding The percentage by weight is: 0.8% of cellulase, 1.5% of hemicellulase, 0.7% of pectinase, 2.5% of ethylenediamine, and the balance is water;

[0053] (2) Continuous flash explosion treatment:

[0054] After soaking is completed, filter out and place in a continuous flash explosion machine for continuous flash explosion treatment. The rotating speed of the flash explosion machine is 750rpm, and the number of times of flash explosion treatment is 25 times. After completion, it is taken out for subsequent use;

[0055]...

Embodiment 3

[0066] A preparation method of Chinese medicine powder Fangji extract, comprising the steps of:

[0067] (1) Soaking treatment:

[0068] Immerse the dried roots of Fenji Fenji in the treatment solution, then place the treatment solution in an ultrasonic environment for shaking treatment, the shaking speed is 120rpm, the shaking treatment time is 2h, the frequency of the ultrasonic wave is 50kHz, each component in the treatment solution and the corresponding weight The percentages are: 0.9% cellulase, 2% hemicellulase, 0.8% pectinase, 3% ethylenediamine, and the balance is water;

[0069] (2) Continuous flash explosion treatment:

[0070] After the soaking is completed, filter out and place in a continuous flash explosion machine for continuous flash explosion treatment. The speed of the flash explosion machine is 800rpm, and the number of flash explosion treatments is 30 times. After completion, it is taken out for subsequent use;

[0071] (3) Superfine pulverization treatme...

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PUM

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine powder radix stephaniae tetrandrae extract, and belongs to the technical field of traditional Chinese medicine active ingredient extraction. (2) continuous flash explosion treatment; (3) carrying out superfine grinding treatment; (4) primary extraction; (5) performing cryogenic crushing; (6) secondary extraction; and (7) purification. The technologies such as soaking, ultrasonic wave and flash explosion treatment are applied to preparation of the radix stephaniae tetrandrae extract, the extraction rate of active ingredients can be effectively increased, and the bioavailability of the radix stephaniae tetrandrae is improved.

Description

technical field [0001] The invention belongs to the technical field of extraction of active ingredients of traditional Chinese medicines, and in particular relates to a preparation method of extracts of traditional Chinese medicine powder Fangji. Background technique [0002] Tetrandrine mainly has the following major functions: (1) Anti-allergy: It is similar to the anti-allergy effect of adrenal cortex hormone, but it does not affect the immune function of the body. (2) Anti-inflammatory: a broad-spectrum anti-inflammatory drug that has the effect of corticosteroids in inhibiting contact dermatitis. (3) Analgesia: It has obvious inhibitory effect on pain caused by allergies, edema and neuralgia. (4) Detumescence: It can effectively suppress skin redness, swelling, itching and other symptoms caused by allergens. (5) Immunity regulation: The root cause of skin allergies is that the skin's own immune system is destroyed and the barrier function of the skin is lost. Tetrandr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/59A61K31/4748A61K125/00
CPCA61K36/59A61K31/4748A61K2236/15A61K2236/39A61K2236/19A61K2236/331
Inventor 梅海平付琴花
Owner 上海浙星新型材料科技有限公司
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