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Liposome skin repair preparation and preparation method thereof

A skin repair and liposome technology, which is applied in liposome delivery, skin diseases, anti-inflammatory agents, etc., can solve the problems of low treatment efficiency and cumbersome medication, and achieve the goal of improving treatment effect, promoting skin activity and eliminating inflammation Effect

Pending Publication Date: 2022-05-13
成都科建生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, clinically, a combination of internal and external medicines is mostly used for treatment, and external medicines are usually divided into lotions and liniments, which are cumbersome and have problems of low treatment efficiency.

Method used

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  • Liposome skin repair preparation and preparation method thereof
  • Liposome skin repair preparation and preparation method thereof
  • Liposome skin repair preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A liposome skin repair preparation is suitable for seborrheic alopecia and symptoms accompanied by scalp inflammation and increased dandruff. It is an external preparation for head skin, including active components and drug-loaded components.

[0047] Wherein, the active components include 4.5% by weight of white willow bark extract, 1.0% of minoxidil, 0.4% of phytosterol and 0.6% of ceramide.

[0048] The drug-loaded components include 12% soybean lecithin, 6.0% cholesterol and 4.0% hyaluronic acid by weight.

[0049] The liposome skin repair preparation can be prepared as external liniment, spray or lotion and the like.

[0050] The preparation method of this liposome skin repair preparation is:

[0051] S1. Weigh 60.0 g of soybean lecithin, 30.0 g of cholesterol, 20.0 g of hyaluronic acid, 5 g of minoxidil, 3 g of ceramide and 2 g of phytosterol, and add them into absolute ethanol to completely dissolve to prepare solution a, which is set aside.

[0052] S2. Weigh ...

Embodiment 2

[0058] A liposome skin repair preparation is suitable for seborrheic alopecia and symptoms accompanied by scalp inflammation and increased dandruff. It is an external preparation for head skin, including active components and drug-loaded components.

[0059] Wherein, the active components include 3.0% by weight of white willow bark extract, 1.50% of minoxidil, 0.5% of phytosterol and 0.8% of ceramide.

[0060] The drug-loaded components include 10% soybean lecithin, 5.0% cholesterol and 4.5% hyaluronic acid by weight.

[0061] The liposome skin repair preparation can be prepared as external liniment, spray or lotion and the like.

[0062] The preparation method of this liposome skin repair preparation is:

[0063] S1. Weigh 50.0g of soybean lecithin, 25.0g of cholesterol, 22.5g of hyaluronic acid, 7.5g of minoxidil, 4.0g of ceramide and 2.5g of phytosterol, and dissolve them completely in anhydrous ether to prepare solution a, and set aside .

[0064] S2. Weigh 15.0 g of wh...

Embodiment 3

[0070] A liposome skin repair preparation is suitable for seborrheic alopecia and symptoms accompanied by scalp inflammation and increased dandruff. It is an external preparation for head skin, including active components and drug-loaded components.

[0071] Wherein, the active components include 5.0% by weight of white willow bark extract, 0.8% of minoxidil, 0.6% of phytosterol and 1.0% of ceramide.

[0072] The drug-loaded components include 16% soybean lecithin, 8.0% cholesterol and 3.0% hyaluronic acid by weight.

[0073] The liposome skin repair preparation can be prepared as external liniment, spray or lotion and the like.

[0074] The preparation method of this liposome skin repair preparation is:

[0075] S1. Weigh 80.0g of soybean lecithin, 40.0g of cholesterol, 15.0g of hyaluronic acid, 4.0g of minoxidil, 5.0g of ceramide and 3.0g of phytosterol, and dissolve them completely in absolute ethanol to prepare solution a, and set aside .

[0076] S2. Weigh 25.0 g of wh...

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Abstract

The invention provides a liposome skin repair preparation and a preparation method thereof, the liposome skin repair preparation is used for scalp repair, the preparation comprises an active component and a drug carrying component, the active component comprises one or more of a white willow bark extract, minoxidil, phytosterol and ceramide; the medicine carrying component comprises phospholipid, cholesterol and hyaluronic acid, and the phospholipid is any one of soybean phospholipid, hydrogenated lecithin, egg yolk lecithin, dipalmitoyl phosphatidylcholine or dipalmitoyl phosphatidyl ethanolamine. The preparation has the functions of repairing head skin, eliminating skin, diminishing inflammation and preventing and treating alopecia, and has a good treatment effect; the preparation method is simple, easy to operate and stable and reliable in preparation performance.

Description

technical field [0001] The invention belongs to the technical field of liposome preparation, and relates to a liposome skin repair preparation and a preparation method thereof. Background technique [0002] In recent years, with social and economic development, the pace of life has accelerated, work and psychological pressure have increased, lack of sleep, endocrine disorders, and excessive intake of high-fat foods have accelerated the increase in the number of people with hair loss and are showing a younger trend. The clinical causes of hair loss include androgen oversecretion, neurological, fungal infection, endocrine disorders, excessive sebum overflow, nutrition, poor microcirculation and congenital, etc. Among them, oversecretion of androgen and poor blood circulation in the scalp cannot Transporting nutrients to the epidermal hair follicles of the head is one of the important factors causing hair loss. Patients with this type of hair loss are often accompanied by sympt...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/76A61K31/506A61K31/164A61K31/575A61K9/127A61K47/36A61K47/28A61K47/24A61P17/14A61P29/00
CPCA61K36/76A61K31/506A61K31/164A61K31/575A61K9/1277A61K9/0014A61K47/36A61K47/28A61K47/24A61P17/14A61P29/00A61K2300/00
Inventor 孙毅毅陈梨花甘红星羊向新谢来宾
Owner 成都科建生物医药有限公司
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