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Cortical layer target spot determination method and device, electronic equipment and storage medium

A technology for determining methods and targets, applied in the field of medical imaging, can solve the problems of inaccurate determination of targets, difficulty in reflecting functional connections, low repeatability of targets, etc., and achieve the effect of improving accuracy

Pending Publication Date: 2022-04-26
INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the signal-to-noise ratio of rest-fMRI data is low, and the calculation of functional connectivity based on a single rest-fMRI is greatly affected by random errors, resulting in low reproducibility of the identified targets
Moreover, it is difficult to reflect the true functional connection based on a single rest-fMRI, therefore, it will lead to the problem of inaccurate target determination

Method used

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  • Cortical layer target spot determination method and device, electronic equipment and storage medium
  • Cortical layer target spot determination method and device, electronic equipment and storage medium
  • Cortical layer target spot determination method and device, electronic equipment and storage medium

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] figure 1 It is a schematic flow chart of a cortical target determination method provided in Embodiment 1 of the present invention. This embodiment is applicable to the situation where the stimulation target is determined by resting-state functional magnetic resonance data. The method can be determined by the cortical target The apparatus may be implemented in the form of software and / or hardware, and the hardware may be an electronic device. Optionally, the electronic device may be a mobile terminal or the like.

[0034] Such as figure 1 As described, the method of this embodiment specifically includes the following steps:

[0035] S110. Acquire initial resting-state functional magnetic resonance data of a first preset number of whole brain regions of the target subject.

[0036] Wherein, the target object is an object subjected to resting state functional magnetic resonance. The whole brain area may be a collection of various brain regions in the whole brain of the ...

Embodiment 2

[0058] figure 2 It is a schematic flow chart of a cortical target determination method provided in Embodiment 2 of the present invention. On the basis of the above-mentioned embodiments, the method for determining the distribution of brain functional connections and the determination method for target voxels can be found in this The technical scheme of embodiment. Wherein, explanations of terms that are the same as or corresponding to the above embodiments are not repeated here.

[0059] Such as figure 2 As described, the method of this embodiment specifically includes the following steps:

[0060] S210. Acquire initial resting-state functional magnetic resonance data of a first preset number of whole brain regions of the target subject.

[0061] S220. Determine the target brain region of the whole brain region.

[0062] S230. Determine the first spatial coordinates of the hippocampal seed point corresponding to the whole brain region and the second spatial coordinates o...

Embodiment 3

[0102] As an optional implementation manner of the above-mentioned embodiments, image 3 It is a schematic diagram of a cortical target determination method provided in Example 3 of the present invention. Wherein, explanations of terms that are the same as or corresponding to the above embodiments are not repeated here.

[0103] The method of this embodiment specifically includes the following steps:

[0104] It should be noted that the method of this embodiment is illustrated by taking the first preset number of groups as 10 groups and the second preset number of groups as 9 groups.

[0105] 1. Repeat rest-fMRI data acquisition multiple times

[0106] Exemplarily, for each subject (target object), rest-fMRI data (initial resting-state functional magnetic resonance data) are repeatedly collected 10 times (first preset group number). Optionally, in order to limit the acquisition time and ensure that the subjects are in a resting state, each group collects twice; in order to ...

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Abstract

The embodiment of the invention discloses a cortex target spot determination method and device, electronic equipment and a storage medium. The method comprises the following steps: acquiring a first preset group number of initial resting state functional magnetic resonance data of a whole brain area of a target object; determining a target brain region, and determining brain function connection distribution of the target brain region for each group of initial resting state functional magnetic resonance data; combining the first preset group number of brain function connection distributions according to the second preset group number to obtain all brain function connection distribution combinations; for each brain function connection distribution combination, respectively calculating an average value of brain function connection values corresponding to each voxel in the target brain region to obtain average brain function connection distribution of the brain function connection distribution combinations; and determining a target voxel according to the average brain function connection distribution of the brain function connection distribution combination, and determining the space coordinate of the target voxel as the target coordinate of the cortex target of the target object. According to the technical scheme of the embodiment of the invention, the accuracy of target spot positioning is improved.

Description

technical field [0001] Embodiments of the present invention relate to the technical field of medical imaging, and in particular to a cortical target determination method, device, electronic equipment, and storage medium. Background technique [0002] The target location technology based on resting-state functional magnetic resonance imaging is used to regulate the functional connection of the cortico-subcortical network and related brain functions, and can realize individualized target location. [0003] Based on a single rest functional magnetic resonance imaging (rest-fMRI) scan, the coordinates of the strongest resting-state functional connection between each voxel point on the parietal lobe and the hippocampal seed point can be calculated as the subsequent stimulation time. target. However, the signal-to-noise ratio of rest-fMRI data is low, and the calculation of functional connectivity based on a single rest-fMRI is greatly affected by random errors, resulting in low ...

Claims

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Application Information

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IPC IPC(8): G06T7/00G06T7/73
CPCG06T7/0012G06T7/74G06T2207/10096
Inventor 殷涛王贺刘志朋靳静娜崔栋廖文清王欣李颖
Owner INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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