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Sialic acid-containing water-in-oil skin cream and preparation method thereof

A water-in-oil, sialic acid technology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve problems such as lowering the quality of cosmetic products, lowering sialic acid content, gravity stratification, etc., and achieving excellent physical stability. Sexual, moisturizing, easy-to-control effects

Pending Publication Date: 2022-04-15
武汉中科光谷绿色生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] However, the applicant found that when sialic acid was applied to the water-in-oil system, there was a problem of gravity stratification, and further found that if the system was unstable, sialic acid would undergo a degradation reaction in the W / O system, resulting in a decrease in the sialic acid content in the system. The by-products produced at the same time lead to the problem of discoloration in the system, which seriously reduces the quality of cosmetic products

Method used

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  • Sialic acid-containing water-in-oil skin cream and preparation method thereof
  • Sialic acid-containing water-in-oil skin cream and preparation method thereof
  • Sialic acid-containing water-in-oil skin cream and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0036] The present embodiment provides a water-in-oil skin cream containing sialic acid, comprising the following raw materials: 0.5% sialic acid, 0.1% bisabolol, 0.2% vitamin E, cetyl polyethylene glycol / polypropylene glycol-10 / 1 Dimethicone 4%, Lauryl PEG-9 Dimethicone Dimethicone 2%, Sorbitan Sesquioleate 1.5%, Isohexadecane 10% , Polydimethylsiloxane 15%, Magnesium Stearate 0.8%, Zinc Oxide 1%, Methylenebisbenzotriazole Tetramethylbutylphenol 1%, Lipophilic Titanium Dioxide 2%, Glycerin 10% , Xanthan Gum 0.4%, Acrylates / C10-30 Alkyl Acrylate Crosspolymer 0.3%, Triethanolamine 1.2%, EDTA-2Na 0.2%, Magnesium Sulfate 1%, Germall IS-45 0.3% , 0.2% paraben, and the balance is deionized water.

[0037] The preparation method of above-mentioned water-in-oil type skin cream, comprises the steps:

[0038] (1) take each raw material by weight percentage for subsequent use;

[0039] (2) Put deionized water, sialic acid, glycerin, EDTA-2Na, magnesium sulfate, xanthan gum, acrylic ...

Embodiment 2

[0047] The present embodiment provides a water-in-oil skin cream containing sialic acid, comprising the following raw materials: 0.1% sialic acid, 0.5% bisabolol, 0.8% vitamin E, cetyl polyethylene glycol / polypropylene glycol-10 / 1 Dimethicone 2.5%, Lauryl PEG-9 Dimethicone Dimethicone 2%, Sorbitan Sesquioleate 1%, Isohexadecane 10% , Polydimethylsiloxane 10%, Magnesium Stearate 1%, Zinc Oxide 2%, Methylenebisbenzotriazole Tetramethylbutylphenol 0.5%, Lipophilic Titanium Dioxide 1%, Glycerin 15% , Xanthan Gum 0.5%, Acrylates / C10-30 Alkyl Acrylate Crosspolymer 0.2%, Triethanolamine 1.6%, EDTA-2Na 0.2%, Magnesium Sulfate 1.5%, Germall IS-45 0.3%, Paraben 0.1-0.2%, the balance is deionized water.

[0048] The preparation method of the water-in-oil skin cream of the present embodiment is the same as that of Example 1.

Embodiment 3

[0050] The present embodiment provides a water-in-oil skin cream containing sialic acid, comprising the following raw materials: 0.5% sialic acid, 0.5% bisabolol, 0.6% vitamin E, cetyl polyethylene glycol / polypropylene glycol-10 / 1 Dimethicone 2.5%, Lauryl PEG-9 Dimethicone Dimethicone 3%, Sorbitan Sesquioleate 3%, Isohexadecane 15% , Polydimethylsiloxane 20%, Magnesium Stearate 2%, Zinc Oxide 1%, Methylenebisbenzotriazole Tetramethylbutylphenol 0.8%, Lipophilic Titanium Dioxide 2%, Glycerin 12% , Xanthan Gum 0.6%, Acrylates / C10-30 Alkyl Acrylate Crosspolymer 0.2%, Triethanolamine 1.8%, EDTA-2Na 0.25%, Magnesium Sulfate 1.2%, Germall IS-45 0.3%, Paraben 0.2%, the balance is deionized water.

[0051] The preparation method of the water-in-oil skin cream of the present embodiment is the same as that of Example 1.

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Abstract

The invention provides water-in-oil type skin cream containing sialic acid and a preparation method of the water-in-oil type skin cream. The water-in-oil type skin cream containing sialic acid is prepared from the following raw materials in percentage by weight: 0.1 to 2 percent of sialic acid, 0.1 to 1 percent of bisabolol, 0.1 to 1 percent of vitamin E, 3 to 10 percent of emulsifier, 20 to 35 percent of grease, 3 to 10 percent of sun-screening agent, 10 to 20 percent of glycerol, 1 to 10.5 percent of auxiliary materials and the balance of deionized water. The sialic acid in the water-in-oil type skin cream containing sialic acid has a higher retention rate, shows excellent physical stability in a high-temperature acceleration test and a long-term test, remarkably improves the quality of cosmetics, integrates sunscreen, isolation, moisturizing and anti-aging, and has a good application prospect. The composition has the advantages of mild property, small irritation, high moistening degree, easiness in absorption, safety, no toxic or side effect and the like.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a water-in-oil skin cream containing sialic acid and a preparation method thereof. Background technique [0002] The water-in-oil (W / O) system is one of the most commonly used emulsification systems for external cream emulsions. It is an emulsification system in which water is dispersed in oil. Water is the inner phase and oil is the continuous outer phase. As we all know, the stability of the W / O system is greatly affected by temperature changes. At the same time, the high content of oil in the external phase of the W / O system makes the skin feel sticky and thick, not light and refreshing. However, the W / O system is conducive to locking water and moisturizing and resisting external aggression , these properties make it widely used in sunscreen products, but the physical and / or chemical sunscreens in sunscreen products may have potential allergies to human skin. [0003] Siali...

Claims

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Application Information

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IPC IPC(8): A61K8/67A61K8/06A61K8/27A61K8/29A61K8/34A61K8/36A61K8/49A61K8/60A61P29/00A61Q17/04A61Q19/00A61Q19/08
Inventor 李翔宇项威王纪左摇
Owner 武汉中科光谷绿色生物技术有限公司
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