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Optical flow control device based on surface lattice resonance and application thereof

An optofluidics and device technology, applied in the field of optofluidics, can solve the problems of low light absorption rate and low fluid convection speed, and achieve the effects of high absorption, strong local electromagnetic field, and fast fluid convection

Pending Publication Date: 2022-04-08
YANGTZE DELTA REGION INST OF UNIV OF ELECTRONICS SCI & TECH OF CHINE HUZHOU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to overcome the low light absorption rate of traditional plasmonic-based optofluidic devices and the low fluid convection velocity induced thereby, and to provide an optical flow device based on surface lattice resonance. control devices, including substrate layers, thin film layers, periodic nanostructure layers, and liquid environment layers

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  • Optical flow control device based on surface lattice resonance and application thereof
  • Optical flow control device based on surface lattice resonance and application thereof
  • Optical flow control device based on surface lattice resonance and application thereof

Examples

Experimental program
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Embodiment 1

[0036] figure 1 A schematic structural diagram of an optofluidic device based on surface lattice resonance provided by the present invention, the structure includes a substrate layer, a thin film layer, a periodic nanostructure layer, and a liquid environment layer. Wherein the film layer is arranged on the substrate layer, and the unit structure of the periodic nanostructure is a disc, which is arranged on the film layer. A layer of liquid environment is located above the layer of periodic nanostructures.

[0037] in particular:

[0038] The electromagnetic, photothermal and fluid responses of the optofluidic device based on surface lattice resonance in this embodiment are as follows:

[0039] By using the three-dimensional finite element method FEM calculation software COMSOL Multiphysics to conduct calculation simulations and experiments, multidisciplinary problems including optics, thermodynamics and fluid dynamics are studied. The specific parameters are optimized as fo...

Embodiment 2

[0047] Based on Embodiment 1, the embodiment of the present application provides another optofluidic device based on surface lattice resonance. Such as Figure 7 As shown, it is basically the same as in Example 1, the only difference is that the periodic nanostructure is a square nanodisk. Preferably, the nano square disk has a side length of 240nm and a thickness of 40nm.

[0048] Figure 8 , Figure 9 with Figure 10 They are the absorption spectrum, electromagnetic field distribution, light-induced temperature increase distribution, and heat-induced fluid convection distribution diagrams of an optofluidic device based on surface lattice resonance in Example 2 of the present invention, from Figure 8 , Figure 9 with Figure 10 It can be seen that without changing the resonance, the square disk increases the area of ​​the metal nanostructure relative to the disk, thereby increasing the photothermal response of the optofluidic device, that is, the heat generated, thereb...

Embodiment 3

[0050] Based on the surface lattice resonance-based optofluidic device disclosed in Examples 1 and 2, this embodiment discloses an application of a surface lattice resonance-based optofluidic device in disease diagnosis and treatment, which specifically includes the following steps:

[0051] Step 1, placing the optofluidic device based on surface lattice resonance in a microfluidic chamber in a liquid environment;

[0052] Step 2, mixing antigen-modified small-sized nanostructures into the microfluidic chamber, and labeling these beads with fluorescence;

[0053] Step 3, mixing the antibody-modified large-scale nanostructures into the microfluidic chamber;

[0054] Step 4, irradiating the optofluidic device with laser light to generate fluid convection in the microfluidic chamber;

[0055] Step 5, the antigen-modified fluorescently labeled nanostructures collide with the antibody-modified nanostructures under the action of convection and fully carry out the antigen-antibody r...

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Abstract

The invention discloses an optical flow control device based on surface lattice resonance and application thereof, and belongs to the technical field of optical flow control, and the optical flow control device comprises a substrate layer, a thin film layer, a periodic nanostructure layer and a liquid environment layer. Through the interference phenomenon caused by the local surface plasmon resonance generated by the periodic nanostructure layer and the diffraction grating behavior supported by the periodic arrangement of the nanostructure on the metal film layer, the light absorptivity is remarkably improved. Besides, the thin film layer not only can effectively diffuse heat generated by the nanostructures arranged on the thin film layer, but also can enlarge the spatial range of temperature distribution through heat dissipation of the thin film layer, and the photo-thermal response of the device is remarkably improved, so that the flow velocity of fluid convection induced by the thin film layer is increased, and the thermal efficiency of the device is improved. The problem that a traditional plasmon optical flow control device is low in optical flow control rate is solved. The method can be used for medical care diagnosis and prevention and detection of some diseases.

Description

technical field [0001] The invention belongs to the field of optofluidic technology, in particular to an optofluidic device based on surface lattice resonance and its application. Background technique [0002] Optofluidics mainly studies how to control the interaction between light and fluid at the micro-nano scale. In recent years, with the vigorous development of optofluidic technology, the trend of miniaturization, price reduction and more compactness of flow cytometers has gradually become apparent, which will bring great benefits to healthcare diagnosis and preventive detection of certain diseases. convenient. In recent years, in the field of optofluidic research, plasmons have unique properties such as excellent near-field local enhancement, breaking through the light diffraction limit, confining the light field to a sub-wavelength scale, and significant photothermal response. attracted more and more attention. Using the temperature gradient characteristics generate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/01G01N21/552
Inventor 景志敏王志明林峰童鑫
Owner YANGTZE DELTA REGION INST OF UNIV OF ELECTRONICS SCI & TECH OF CHINE HUZHOU
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