Bird's nest acid anti-blue-light nano composition, preparation method and application thereof

A nano-composite, anti-blue light technology, applied in the directions of pharmaceutical formulations, cosmetic preparations, cosmetic preparations, etc., can solve the problems of difficult anti-blue light active ingredients, insignificant anti-blue light effect, unclear anti-blue light mechanism, etc. Improve blue light protection, improve skin penetration, and promote long-term retention

Pending Publication Date: 2022-03-11
WUHAN BEST CARRIER NANO TECH +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In recent years, with the development of science and technology and the improvement of people's living standards, anti-blue light cosmetics have attracted more attention. Although there are endless anti-blue light products on the market, there are still many disadvantages, such as single anti-blue light mechanism or anti- The mechanism of blue light is not clear, some active ingredients are only added conceptually, and the anti-blue light effect is not significant; secondly, some anti-blue light active ingredients such as lutein have poor stability, are sensitive to oxygen, light, and heat, and are easy to oxidize and deteriorate during product placement. Anti-blue light effect; in addition, due to the skin's own barrier, it is difficult for anti-blue light active ingredients to penetrate the stratum corneum into the dermis of the skin and stay in the dermis, greatly reducing the anti-blue light effect

Method used

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  • Bird's nest acid anti-blue-light nano composition, preparation method and application thereof
  • Bird's nest acid anti-blue-light nano composition, preparation method and application thereof
  • Bird's nest acid anti-blue-light nano composition, preparation method and application thereof

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preparation example Construction

[0061] The present invention also provides a preparation method of the bird's nest acid anti-blue light nano composition described in the above technical solution, comprising the following steps:

[0062] Mixing sialic acid, carnosine and part of water to obtain the inner water phase;

[0063] mixing lutein, liquid lipids, emulsifiers, co-emulsifiers and polyols to obtain an oil phase;

[0064] mixing and emulsifying the internal water phase and the oil phase to obtain a water-in-oil internal system;

[0065] mixing the cotyledon leaf / stem extract, the cocoa seed extract and the remaining amount of water to obtain the external aqueous phase;

[0066] mixing and emulsifying the water-in-oil internal system and the external water phase to obtain a water-in-oil-in-water bicontinuous system;

[0067] Micronizing the water-in-oil-in-water bicontinuous system to obtain a micron-scale dispersion;

[0068] The micron-scale dispersion is subjected to nano-processing to obtain the blue...

Embodiment 1

[0085] According to the mass percentage, add 20% bird's nest acid and 10% carnosine to 60% purified water, heat and dissolve in a water bath at 50°C to obtain the inner water phase;

[0086] Mix 0.1% lutein, 1% olive oil, 4% PEG-10 oleate, 3% PPG-24-glyceropolyether-24, and 1% glycerin, heat and dissolve in a water bath at 50°C to obtain an oil phase;

[0087] Add the inner water phase dropwise to the oil phase at a rate of 3 drops / second and keep stirring at 50°C and a rotation rate of 700r / min to obtain an inner water-in-oil system;

[0088] Add 0.1% of the leaf / stem extract of E. capitulum and 0.1% of the cocoa seed extract to 0.7% of purified water, heat and dissolve in a water bath at 50°C to obtain the outer aqueous phase;

[0089] (Specifically, add 20g of bird's nest acid and 10g of carnosine to 60g of purified water, heat and dissolve in a water bath at 50°C to obtain the inner water phase;

[0090] Mix 0.1g of lutein, 1g of olive oil, 4g of PEG-10 oleate, 3g of PPG-...

Embodiment 2

[0098] Add 18% sialic acid and 5% carnosine to 58% purified water, heat and dissolve in a water bath at 50°C to obtain the inner water phase;

[0099] Mix 0.5% lutein, 4% hydrogenated linseed oil, 1% polyglycerol-10 dipalmitate, 8% oleyl polyether-12, 3% polyethylene glycol-200, heat and dissolve in a water bath at 50°C, get the oily phase;

[0100] Add the inner water phase dropwise to the oil phase at a rate of 4 drops / second and stir continuously at 50°C and a rotation rate of 600r / min to obtain an oil-in-water inner system;

[0101] Add 0.5% of the leaf / stem extract of E. capitulum and 0.5% of the cocoa seed extract to 1.5% of purified water, heat and dissolve in a water bath at 50°C to obtain the outer water phase;

[0102]Add the water-in-oil internal system dropwise to the external water phase at a rate of 4 drops / second and continuously stir at 50°C and a rotation rate of 600r / min to obtain a water-in-oil-in-water bicontinuous system;

[0103] The water-in-oil-in-wat...

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Abstract

The invention relates to the technical field of cosmetics, in particular to a sialic acid anti-blue-light nano composition, a preparation method and application thereof. The invention provides a sialic acid anti-blue-light nano composition. The sialic acid anti-blue-light nano composition comprises an anti-blue-light active component and an auxiliary material, the anti-blue-light active components comprise sialic acid, carnosine, xanthophyll, lespedeza head cotyledon / stem extract and cocoa seed extract; the auxiliary materials comprise an emulsifier, a co-emulsifier, polyol, liquid lipid and water. According to four chemical anti-blue-light mechanisms of absorbing radiation, improving hyperpigmentation, regulating physiological rhythm and delaying skin aging, five anti-blue-light active components are entrapped together, and are reasonably matched according to the proportion in the anti-blue-light anti-blue-light active components to achieve synergistic interaction. The nano composition disclosed by the invention can effectively improve the stability of active matters, the skin penetration amount and the skin retention amount, is mild and non-irritant to the skin, and can be widely applied to cosmetics.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a bird's nest acid anti-blue light nano composition, a preparation method and an application thereof. Background technique [0002] Blue light is visible light with high energy between 400nm and 480nm. It is found in our most common sunlight. In addition, blue light also exists in digital products such as mobile phones and computers. Compared with ultraviolet rays, blue light has a stronger penetrating power to the skin, and can penetrate the surface layer of the skin to reach the dermis, so its damage to the skin is no less than that of ultraviolet rays. Prolonged exposure to blue light and the use of electronic products will cause vision loss, and the damage to the skin is mainly manifested as melanin pigmentation, loose and inelastic skin, and accelerated skin aging. [0003] In cosmetics, different anti-blue light technologies have different mechanisms of action, mainly in...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/60A61K8/64A61K8/34A61K8/06A61Q17/04A61Q19/08A61Q19/00
CPCA61K8/9789A61K8/60A61K8/64A61K8/345A61K8/066A61Q17/04A61Q19/08A61Q19/00A61K2800/782A61K2800/5922A61K2800/413A61K2800/412A61K2800/805Y02A50/30
Inventor 刘卫李翔宇王曦肖敏陈丹胡雄沈慧慧雷俊华
Owner WUHAN BEST CARRIER NANO TECH
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