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Application of alpinia zerumbet volatile oil in preparation of medicine for treating hyperuricemia

A technology of hyperuricemia and ginger volatile oil, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the undiscovered problems such as the application of volatile oil of Alpinia japonicus, and achieve the effect of improving kidney function and reducing serum uric acid level

Active Publication Date: 2022-02-11
GUIZHOU MEDICAL UNIV
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Problems solved by technology

But at present, the application of the volatile oil of Alpinia japonicus in the treatment of hyperuricemia has not been found

Method used

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  • Application of alpinia zerumbet volatile oil in preparation of medicine for treating hyperuricemia
  • Application of alpinia zerumbet volatile oil in preparation of medicine for treating hyperuricemia
  • Application of alpinia zerumbet volatile oil in preparation of medicine for treating hyperuricemia

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Embodiment

[0019] Application of the volatile oil of Alpinia japonicus in the preparation of medicine for treating hyperuricemia.

[0020] 1. Experimental method

[0021] 1.1 Extraction and preparation of volatile oil of Alpinia japonicus

[0022] Crush the dried fruit of Alpinia galanga until the seeds burst, take a uniform sample according to the requirements of the Pharmacopoeia, accurately weigh 500g, add 12 times of distilled water to soak for 1 hour, extract for 7 hours according to the 2020 edition of "Chinese Pharmacopoeia" (Part Four) general rule 2204 volatile oil determination method, and collect the volatile oil. After drying over anhydrous sodium sulfate, store in a -20°C refrigerator for future use.

[0023] 1.2 Construction of mouse hyperuricemia model

[0024] Get 50 healthy SPF grade Kunming male mice, and randomly divide them into blank group, model group (oxonate potassium group, 250mg / kg), positive group (allopurinol group, 35mg / kg), high-dose Alpinia japonicus gro...

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Abstract

The invention discloses an application of alpinia zerumbet volatile oil in the preparation of a medicine for treating hyperuricemia, and belongs to the technical field of medicines. It is found that the alpinia zerumbet volatile oil has the characteristics of effectively reducing the serum uric acid level and improving the renal function.

Description

technical field [0001] The invention relates to the medicinal application of the volatile oil of Alpinia japonicus, in particular to the application of the volatile oil of Alpinia japonicus in the preparation of medicines for treating hyperuricemia. Background technique [0002] Hyperuricemia (HUA) is a metabolic disease characterized by high uric acid caused by abnormal purine metabolism. How to effectively prevent and treat hyperuricemia has become a research hotspot in the medical field. From the perspective of traditional medical syndrome differentiation, elevated blood uric acid is caused by filling the body with ointment, poor circulation of qi and blood, accumulation into turbidity, or further flow into the meridian, which belongs to the category of "turbidity of uric acid". Traditional Chinese medicine believes that the treatment of hyperuricemia needs to be treated based on overall differentiation and treatment, grasping the method of dredging the internal organs a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P19/06A61P13/12A61K131/00
CPCA61K36/9062A61P19/06A61P13/12A61K2236/331A61K2236/51Y02A50/30
Inventor 沈祥春吴林菁陈英肖婷周雪张彦燕张嫩玲姜丰陶玲
Owner GUIZHOU MEDICAL UNIV
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