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Implant for reconstruction of nipple-areola complex, and method for producing same

A technology of implants and composites, which is applied in the directions of processing and manufacturing, manufacturing tools, and additive manufacturing, etc., can solve problems such as limitations, lower aesthetic and psychological satisfaction of patients, and lower height of surgical nipples, and achieve a high implantation rate.

Pending Publication Date: 2021-12-21
T&R BIOFAB +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] For methods using acellular dermal matrix, the absorption of acellular dermal matrix results in a reduction in the height of the surgical nipple, and the use of acellular dermal matrix is ​​limited in reproducing the appearance of a normal nipple, thereby reducing aesthetic and psychological satisfaction of patients

Method used

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  • Implant for reconstruction of nipple-areola complex, and method for producing same
  • Implant for reconstruction of nipple-areola complex, and method for producing same
  • Implant for reconstruction of nipple-areola complex, and method for producing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Implant samples (10mm×40mm×0.8mm) were prepared using 3D printing. Specifically, polycaprolactone (PCL) was extruded through a 3D printer head, and microfibers with a diameter of 500 μm were stacked at intervals of 500 μm to prepare implanted samples with a porosity of 50%.

Embodiment 2

[0075] Fabrication of implants for nipple-areolar complex reconstruction using 3D printing. Specifically, polycaprolactone (PCL) was extruded through a 3D printer head, and microfibers with a diameter of 500 μm were laminated into a disc shape to form a support. The same steps are then carried out to form a cylindrical body at the upper end of the support. As a result, implants for reconstruction of the nipple-areolar complex were manufactured. In order to obtain an implant for nipple-areolar complex reconstruction with a porosity of 50%, the interval between microfibers was set at 500 μm. 3D printing was performed under the condition that the diameter of the main body was set to 10 mm and the height thereof was set to 5 mm. Image 6 The implant for reconstructing the nipple-areolar complex thus manufactured is shown.

experiment example 1

[0076] [Experimental Example 1: Evaluation of Ease of Tissue Penetration]

[0077] The implanted samples prepared according to Example 1 were implanted into the subcutaneous tissue of rabbits, and the degree of biological tissue penetration into the implanted samples was evaluated over 12 months. The results are shown in Figure 7 middle.

[0078] Figure 7 The results showed that biological tissue penetrated between the voids of the implanted samples and that the volume of the implanted samples was maintained even after 12 months after implantation.

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Abstract

The present invention relates to: an implant for the reconstruction of the nipple-areola complex; and a method for producing same. The implant for the reconstruction of the nipple-areola complex according to the present invention can be implanted along a central axis inside autologous tissue during nipple-areola complex reconstruction surgery to form a normal nipple-areola complex shape. In addition, the nipple-areola complex implant according to the present invention, due to being formed of a porous structure, has similar flexibility to normal nipple-areola complex tissue, and exhibits a high engraftment rate with autologous tissues since the surrounding tissue can permeate into the implant through the voids thereof following implantation.

Description

technical field [0001] The present invention relates to an implant for reconstruction of the nipple-areolar complex (NAC) and a manufacturing method thereof. More specifically, the present invention relates to an implant for nipple-areolar complex (NAC) reconstruction and a method of manufacturing the same, wherein the implant can be used along the central axis of the breast inside autologous tissue during nipple-areolar complex reconstruction surgery. Implanted to restore the nipple-areolar complex to a near-normal shape. Background technique [0002] Reconstruction of the nipple-areolar complex (NAC) is the final step in breast reconstruction. Although reconstruction is a simple procedure, it brings high aesthetic and psychological satisfaction to patients. [0003] Patients requiring NAC reconstruction have both congenital and acquired factors. Most acquired factors are caused by total mastectomy after removal of malignant tumors such as breast cancer. [0004] In par...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/12B33Y80/00B33Y10/00A61L27/14A61L27/56B33Y70/00B29C64/106A61F2/00
CPCA61F2/12B33Y80/00B33Y10/00A61L27/14A61L27/56B33Y70/00B29C64/106A61F2/0063A61F2/00A61F2/0059C08L67/04C08L75/04A61L2430/04A61L27/50A61L27/18A61L27/16B29C64/118A61F2240/004A61F2230/0069A61F2230/0093A61F2250/0023C08L23/06A61F2240/002B29C64/209
Inventor 崔多美李正锡沈镇亨尹元洙李重澔
Owner T&R BIOFAB
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