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Exosome-containing anti-aging essence and preparation method thereof

A technology of exosomes and essence, applied in the field of biomedicine, can solve the problem of poor anti-aging and anti-wrinkle effects of essence, achieve the effect of promoting fibroblast proliferation and collagen synthesis, simplifying components, and reducing skin burden

Pending Publication Date: 2021-12-07
李俊
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of the above-mentioned prior art, the present invention provides an anti-aging essence containing exosomes and a preparation method thereof to solve the problem of poor anti-aging and anti-wrinkle effects of the existing essence

Method used

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  • Exosome-containing anti-aging essence and preparation method thereof
  • Exosome-containing anti-aging essence and preparation method thereof
  • Exosome-containing anti-aging essence and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] An anti-aging essence containing exosomes, based on a total mass of 100 parts, comprising the following components by mass: 0.05 parts of umbilical cord stem cell exosomes, 20 parts of rose hydrosol, 8 parts of glycerin, fermented bifid yeast 3 parts of product lysates, 2 parts of hyaluronic acid, 3 parts of white fungus extract, 2 parts of oligopeptide-1, 1.5 parts of hydrolyzed collagen, 0.5 parts of carnosine, 0.1 parts of carbomer U20, 0.2 parts of EDTA-2Na, antibacterial agent 0.1 part, triethanolamine 0.1 part, and the rest is sterile water.

[0033] Among them, umbilical cord stem cell exosomes are prepared through the following steps:

[0034] (1) The fresh umbilical cord is soaked in physiological saline containing penicillin. After removing the residual blood stains, the blood vessels in the umbilical cord are removed, and then the Wharton's jelly in the umbilical cord is peeled off, and then cut into pieces of 1mm. 3 pieces of size;

[0035] (2) Inoculate t...

Embodiment 2

[0048] An anti-aging essence containing exosomes, based on a total mass of 100 parts, comprising the following components by mass: 0.1 parts of umbilical cord stem cell exosomes, 30 parts of rose hydrosol, 10 parts of glycerin, fermented bifid yeast 4 parts of product lysates, 4 parts of hyaluronic acid, 2 parts of white fungus extract, 3 parts of oligopeptide-1, 1 part of hydrolyzed collagen, 0.3 parts of carnosine, 0.2 parts of carbomer U20, 0.8 parts of EDTA-2Na, antibacterial 0.3 parts of agent, 0.2 parts of triethanolamine, and the rest are sterile water.

[0049] Among them, umbilical cord stem cell exosomes are prepared through the following steps:

[0050] (1) The fresh umbilical cord was soaked in normal saline containing streptomycin, and after removing the residual blood stains, the blood vessels in the umbilical cord were removed, and then the Wharton's jelly in the umbilical cord was peeled off, and then cut into pieces of 1mm 3 pieces of size;

[0051] (2) Inocul...

Embodiment 3

[0064] An anti-aging essence containing exosomes, based on 100 parts by mass, comprising the following components by mass: 0.07 parts of umbilical cord stem cell exosomes, 25 parts of rose hydrosol, 9 parts of glycerin, and fermented bifid yeast 4 parts of product lysates, 3 parts of hyaluronic acid, 5 parts of white fungus extract, 2 parts of oligopeptide-1, 2 parts of hydrolyzed collagen, 0.7 parts of carnosine, 0.2 parts of carbomer U20, 0.5 parts of EDTA-2Na, antibacterial 0.2 part of agent, 0.1 part of triethanolamine, and the rest is sterile water.

[0065] Umbilical cord stem cell exosomes are produced through the following steps:

[0066] (1) The fresh umbilical cord is soaked in normal saline containing penicillin. After removing the residual blood stains, the blood vessels in the umbilical cord are removed, and then the Wharton's jelly in the umbilical cord is peeled off, and then cut into pieces of 1mm. 3 pieces of size;

[0067] (2) Inoculate the resulting fragme...

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Abstract

The invention discloses exosome-containing anti-aging essence and a preparation method thereof. The exosome-containing anti-aging essence, in 100 parts by total mass, comprises the following components in parts by mass: 0.05 to 0.1 part of umbilical cord stem cell exosome, 20 to 30 parts of rose hydrosol, 8 to 10 parts of glycerol, 4 to 5 parts of bifidus yeast fermentation product lysate, 2 to 4 parts of hyaluronic acid, 3 to 6 parts of tremella fuciformis extract, 2 to 3 parts of oligopeptide-1, 1 to 2 parts of hydrolyzed collagen, 0.3 to 0.7 part of carnosine, 0.1 to 0.2 part of Carbomer U20, 0.2 to 0.8 part of EDTA-2Na, 0.1 to 0.3 part of antibacterial agent, 0.1 to 0.2 part of triethanolamine and the balance of sterile water. The exosome-containing essence disclosed by the invention uses simple components, adopts an oil-free formula, is refreshing in use feeling, does not need to be emulsified, and has the effects of preserving moisture for a long time, preventing skin aging and stretching wrinkles.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to an anti-aging essence containing exosomes and a preparation method thereof. Background technique [0002] The skin is the organ with the largest surface area of ​​the human body, covering the surface of the human body. However, with age and various external environment violations, facial skin will appear wrinkles, sagging, dark yellow and other aging problems. Caring for the skin with various anti-aging skin care products has become a daily routine for consumers. With the development of the skin care product market, consumers’ demand for skin care products is no longer satisfied with simple water, milk, and cream. More and more people demand a high-performance, nutritious skin care product category——essence liquid. [0003] Exosomes are small vesicles of 40-200nm secreted by living cells, carrying various proteins, mRNA, micro-RNA and lipid substances, which can...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/65A61K8/49A61K38/01A61K35/28C12N5/0775A61Q19/00A61Q19/08A61P17/18A61P17/16A61K31/047A61K31/4172A61K31/728
CPCA61K8/99A61K8/65A61K8/4946A61K35/28A61K38/014A61K31/4172A61K36/07A61K31/728A61K31/047A61Q19/08A61Q19/00C12N5/0668A61P17/18A61P17/16A61K2800/592C12N2509/10C12N2509/00A61K2300/00
Inventor 李俊
Owner 李俊
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