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Compound fermentation product, skin external preparation containing compound fermentation product and preparation method and application of compound fermentation product

A technology of composite fermented products and fermented substrates, applied in skin care preparations, medical preparations containing active ingredients, cosmetic preparations, etc., can solve the problem of low utilization of oat bran and difficult screening of active ingredients, There are many problems in the process of plant extraction, so as to achieve the effect of good skin tightening effect, low cost and simple preparation process

Pending Publication Date: 2021-11-16
BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is to overcome the low availability of oat bran in the prior art, and there are many plant extraction processes, so it is difficult to screen out a method that is convenient for extracting active ingredients from oat bran and acerola powder that can be used in the field of cosmetics and other deficiencies, providing a compound fermented product, including its skin external preparation and its preparation method and application

Method used

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  • Compound fermentation product, skin external preparation containing compound fermentation product and preparation method and application of compound fermentation product
  • Compound fermentation product, skin external preparation containing compound fermentation product and preparation method and application of compound fermentation product
  • Compound fermentation product, skin external preparation containing compound fermentation product and preparation method and application of compound fermentation product

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preparation example Construction

[0064] 1. Preparation of YWY-1 bacterial solution in the following examples

[0065] (1) Inoculate YWY-1 on dextrose potato agar (PDA) medium and culture at 28°C for 2 days (for activation);

[0066] (2) inoculate the single bacterium colony obtained in step (1) into 100mL YPD medium (composed of: glucose 2%, peptone 1%, yeast extract 0.5%), and culture at 28°C and 180rpm for 24h to obtain YWY-1 bacterium liquid, The concentration is roughly 10 8 CFU / mL.

[0067] 2. Preparation of lactic acid bacteria liquid in the following examples

[0068] Inoculate Lactobacillus delbrueckii subsp. bulgaricus with a preservation number of CGMCC No.1.16075 in a lactic acid bacteria medium (MRS medium), and culture it statically in a constant temperature shaking incubator at 45°C for 24 hours to obtain a lactic acid bacteria liquid for inoculation. The concentration is about 10 10 CFU / mL.

[0069] 3, the preparation of composite fermentation substrate in following embodiment and comparat...

Embodiment 1

[0072] Inoculate 24mL of YWY-1 bacterial liquid into 300mL of composite fermentation substrate, and ferment and cultivate for 48 hours at a temperature of 28°C with stirring, and the stirring speed is 150rpm; the prepared material is transferred to a centrifuge, and Centrifuge at 5500 rpm for 20 minutes, collect the supernatant, and sterilize the supernatant at 121°C for 15 minutes; after sterilization, cool down and add preservatives accounting for 2.8% of the supernatant at 45°C Mixed solution, antiseptic The mixed solution contains 2.3 parts of ethylene glycol and 0.5 part of pentanediol to prepare a compound fermented product.

[0073] The pH value of the prepared composite fermented product is 4.8, and the solid content is 3.3%. The solid content refers to the percentage of the mass of the remaining solid after the composite fermented product is dried to the mass of the composite fermented product.

Embodiment 2

[0075] (1) Inoculate 24mL of YWY-1 bacterial liquid into 300mL of composite fermentation substrate, and ferment and cultivate for 48 hours at a temperature of 28°C under stirring conditions, and the stirring speed is 150rpm; after fermentation, at a temperature of 121 Sterilize at ℃ for 15 minutes to obtain material A;

[0076] (2) Inoculate 30mL of lactic acid bacteria liquid into the material A prepared in step (1), and ferment and cultivate for 8 hours at a temperature of 45°C; The supernatant was centrifuged for 20 minutes, and the supernatant was sterilized at 121°C for 15 minutes; after sterilization, the temperature was lowered, and a preservative mixture accounting for 2.8% of the supernatant was added at 45°C. The preservative mixed solution contains 2.3 parts of ethylene glycol and 0.5 part of pentylene glycol to obtain a composite fermented product.

[0077] The pH value of the prepared composite fermented product is 4.9, and the solid content is 3.4%. The solid co...

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Abstract

The invention discloses a compound fermentation product, a skin external preparation containing the compound fermentation product and a preparation method and application of the compound fermentation product. The preparation method of the compound fermentation product comprises the following steps: inoculating a fermentation strain into a fermentation substrate, and carrying out fermentation culture and sterilization, wherein the fermentation substrates are oat bran, acerola cherry extract and water; and the fermentation strain is a mixed strain of lactic acid bacteria and saccharomycetes or saccharomycetes. The prepared compound fermentation product has a good anti-oxidation effect and a skin tightening effect, the toxicity to human skin fibroblasts is remarkably reduced, and the compound fermentation product is safe to use, free of skin irritation and capable of being widely applied to the field of cosmetics.

Description

technical field [0001] The invention belongs to the technical field of fermentation, and in particular relates to a composite fermented product, including the skin external preparation and its preparation method and application. Background technique [0002] Oatmeal is rich in high fat, protein, amino acid, vitamins, minerals and dietary fiber and other substances. intestinal flora, anti-cancer and anti-inflammatory effects. As a functional raw material, oat has a wide range of applications in food, feed, medicine, cosmetics and industrial raw materials. The oat bran is the husk on the surface of oats, which will protect the oats. During the oat processing process, the oat bran will be filtered out as waste. In recent years, it has been reported that oat bran contains a large amount of protein and dietary fiber, which has the effects of lowering blood sugar, blood fat and cleaning the intestinal tract, and has become a favorite food for dieters, making it widely concerned ...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9789A61K8/99A61K8/9728A61Q19/08
CPCA61K8/9794A61K8/9789A61K8/99A61K8/9728A61Q19/08A61K2800/85
Inventor 王昌涛张佳婵赵丹李萌王冬冬程文静
Owner BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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