Skin whitening and brightening freeze-drying preparation, whitening and brightening freeze-drying essence and preparation method thereof

A freeze-dried preparation and whitening technology, applied in the field of beauty and skin care, can solve the problems of limited whitening effect and inability to form synergistic effects, and achieve good whitening effect

Pending Publication Date: 2021-10-22
常州伟博海泰生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, most of the whitening and brightening products on the market are simple superposition of whitening ingredients, which cannot form a synergistic effect. From the perspective of principle, there is no joint solution to whitening by inhibiting the formation of melanin in the body, decomposing existing melanin in the skin, and moisturizing and promoting metabolism. Problem, limited whitening effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] This example introduces several raw material formulas of whitening and brightening freeze-dried preparations or whitening and brightening freeze-dried essences.

1.1

[0079] Its raw material formula comprises according to mass parts:

[0080] 0.01 part of vitamin C, 50 parts of licorice extract, 10 parts of hyaluronic acid, 20 parts of glycerin, 60 parts of squalane, 0.4 part of dextran, 0.1 part of chitosan, 0.5 part of PVP and 100 parts of water.

1.2

[0081] Its raw material formula comprises according to mass parts:

[0082] 40 parts of kiwi fruit extract, 35 parts of orange extract, 5 parts of nicotinamide, 0.01 part of resveratrol, 2 parts of hyaluronic acid, 9 parts of wheat germ oil, 5 parts of α-mannan, 2 parts of albumin, 1 part of modified starch, 1.5 parts of skeleton support agent, 1.5 parts of skin feeling improving agent and 100 parts of water.

1.3

[0083] Its raw material formula comprises according to mass parts:

[0084] 28 parts of licorice ...

Embodiment 2

[0088] This example introduces the preparation method of lyophilized preparation or lyophilized essence.

2.1

[0089] Include the following steps:

[0090] Step 1: Prepare the suspension

[0091] Weigh, pulverize, mix, and disperse the suspension according to the ingredients and mass parts in the raw material formula of 1.1 in Example 1, wherein the particle diameter of the solid active ingredient is 50 mesh, and the viscosity of the suspension is 1000 centipoise , with a density of 0.8g / cm 3 ;

[0092] Step 2: Packing

[0093] Filling the resulting suspension into a product mold, which is a blister;

[0094] Step 3: Prefreeze

[0095] The mold filled with the mixed liquid is quickly frozen by direct injection of liquid nitrogen at -196°C, and pre-frozen to obtain the intermediate state of the freeze-dried essence;

[0096] Step 4: Sublimation Drying

[0097] The intermediate state of the freeze-dried essence was sublimated and dried at -50°C for 10 hours;

[0098] S...

Embodiment 3

[0134] This example introduces the use of the whitening and brightening freeze-dried preparation or whitening and brightening freeze-dried essence prepared in Example 2.

[0135] product number 2.1 2.2 2.3 2.4 product shape Three-dimensional shape spherical flaky irregular shape Dissolution rate 1min 93％ 92％ 95％ 93％ reconstitution rate 10s 8s 5s 9s water content 5％ 4％ 3％ 4％

[0136] The dissolution rate refers to the ratio of active ingredients dissolved in distilled water within 1 min to the total active ingredients after the whitening and brightening freeze-dried preparation or whitening and brightening freeze-dried essence is added to distilled water.

[0137] The redissolution rate refers to the time required for diluting and shaking with distilled water to dissolve into a uniform emulsion without solids.

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Abstract

The invention discloses a skin whitening and brightening freeze-drying preparation which is prepared from the following raw materials in parts by mass: 0.01 to 80 parts of a first whitening component capable of inhibiting activity of tyrosinase, 0.01 to 50 parts of a second whitening component capable of removing free radicals generated by ultraviolet rays, 0.01 to 90 parts of a moisturizing component, 0.01 to 40 parts of a freeze-drying binder and 100 parts of water. From the perspective of principle, the whitening problem is solved by inhibiting formation of melanin in the body, decomposing melanin existing in the skin and moisturizing and promoting metabolism, and the whitening and brightening effect is good. The invention further discloses a preparation method of the skin whitening and brightening freeze-drying preparation, and the product obtained through the key steps of pre-freezing, sublimation drying, desorption drying and the like is smooth in appearance and good in redissolution rate.

Description

technical field [0001] The invention relates to the technical field of beauty and skin care, in particular to a freeze-dried preparation for whitening and brightening skin, a freeze-dried essence for whitening and skin brightening and a preparation method thereof. Background technique [0002] Whitening is achieved by inhibiting the formation of melanin in the body or decomposing existing melanin in the skin. [0003] There are six different colors of human skin, mainly due to the difference in the amount and distribution of melanin in the skin. Melanin is contained in melanocytes in the cortical layer of the epidermis, which are very fine tan and dark brown particles. When it is disturbed by internal and external conditions, such as ultraviolet radiation and enhanced tyrosinase activity, it will be released from melanocytes, resulting in whitening problems. [0004] Melanin is essentially a protein that exists in the middle of the cells in the basal layer of the skin. At ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/31A61K8/34A61K8/36A61K8/44A61K8/60A61K8/65A61K8/67A61K8/73A61K8/92A61K8/9789A61Q19/00A61Q19/02
CPCA61K8/676A61K8/673A61K8/44A61K8/36A61K8/347A61K8/735A61K8/345A61K8/31A61K8/60A61K8/65A61K8/9794A61K8/9789A61K8/922A61Q19/02A61Q19/00A61K2800/782A61K2800/84A61K2800/592
Inventor 李和伟
Owner 常州伟博海泰生物科技有限公司
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