Composition with function of simultaneously reducing blood sugar and blood fat and preparation method thereof

A composition and blood lipid technology, applied in the field of medicine, can solve the problems of inconvenient medication, slow onset of traditional Chinese medicine and the like

Active Publication Date: 2021-10-15
HEBEI YUZHILIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the complex pathogenesis of diabetes, humans have not yet found a cure, which means that patients need to receive treatment for life. At present, Western medicine is still the main clinical drug, but because of many adverse reactions such as hypoglycemia and gastrointestinal reactions , so the goal of finding high-efficiency, low-toxicity and hypoglycemic drugs needs to be realized urgently
[0008] Compared with western medicine, traditional Chinese medicine has the advantages of safety, less side effects, no damage to the gastrointestinal tract, and less stimulation to the liver and kidney, and has attracted people's attention. However, traditional Chinese medicine has the problems of slow onset of effect and inconvenient medication. Research and development of new anti-diabetic traditional Chinese medicine preparations in Chinese herbal medicine is of great significance and broad prospects

Method used

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  • Composition with function of simultaneously reducing blood sugar and blood fat and preparation method thereof
  • Composition with function of simultaneously reducing blood sugar and blood fat and preparation method thereof
  • Composition with function of simultaneously reducing blood sugar and blood fat and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A preparation method of a composition with the function of simultaneously lowering blood sugar and blood lipids, comprising the steps of:

[0035] A, take by weighing 180 parts of fenugreek extract, 90 parts of mulberry leaf extract, 90 parts of burdock fruit extract, 40 parts of balsam pear extract, 10 parts of yeast chromium, and pulverize to obtain a raw material mixture;

[0036] B. Weigh an appropriate amount of purified water, and configure a hydroxypropyl cellulose solution with a mass fraction of 2%.

[0037] C. In the raw material mixture, add an appropriate amount of hydroxypropyl cellulose solution, the mass ratio of the raw material mixture to the binder solution is 5:0.5, and prepare a soft material (it can form agglomerates when pinched by hand, and can be disintegrated by light pressure with fingers. open), dried at 45°C, passed through a 20-mesh sieve and shaken to granulate to obtain granules, which were packed into hard gelatin capsules to obtain capsu...

Embodiment 2

[0039] A preparation method of a composition with the function of simultaneously lowering blood sugar and blood lipids, comprising the steps of:

[0040] A, take by weighing 180 parts of fenugreek extract, 130 parts of mulberry leaf extract, 100 parts of burdock fruit extract, 80 parts of balsam pear extract, 15 parts of yeast chromium, and pulverize to obtain a raw material mixture;

[0041] B. Weigh an appropriate amount of ethanol and configure a 5% polyvinylpyrrolidone solution by mass fraction.

[0042] C. Add an appropriate amount of polyvinylpyrrolidone solution to the raw material mixture, the mass ratio of the raw material mixture to the binder solution is 5:0.2, and prepare a soft material (it can form agglomerates when pinched by hand, and can be broken apart by light pressure with fingers) , dried at 40°C, passed through a 20-mesh sieve and shaken to granulate to obtain granules, which were packed into hard gelatin capsules to obtain capsules.

Embodiment 3

[0044] A preparation method of a composition with the function of simultaneously lowering blood sugar and blood lipids, comprising the steps of:

[0045] A, take by weighing 220 parts of fenugreek extract, 140 parts of mulberry leaf extract, 140 parts of burdock fruit extract, 80 parts of balsam pear extract, 30 parts of yeast chromium, and pulverize to obtain a raw material mixture;

[0046] B. Weigh an appropriate amount of purified water, and configure a water-soluble starch solution with a mass fraction of 15%.

[0047] C. In the raw material mixture, add an appropriate amount of water-soluble starch solution, the mass ratio of the raw material mixture to the binder solution is 5:1, and prepare a soft material (it can form agglomerates when squeezed tightly with hands, and can be broken apart by light pressure with fingers) , dried at 40°C, passed through a 20-mesh sieve and shaken to granulate to obtain granules, which were packed into hard gelatin capsules to obtain caps...

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Abstract

The invention relates to a composition with function of simultaneously reducing blood sugar and blood fat and a preparation method thereof, and particularly, the composition is prepared from the following raw materials in parts by weight: 180-220 parts of a fenugreek extract, 90-140 parts of a mulberry leaf extract, 90-140 parts of a burdock extract, 40-80 parts of a bitter gourd extract and 10-30 parts of chromium yeast. Pharmacological test results show that the pharmaceutical composition is free of allergy and other adverse reactions, and has a good blood fat reducing effect while regulating the body and reducing blood sugar; pharmacological tests show that the pharmaceutical composition belongs to a non-toxic level. Meanwhile, the preparation method of the pharmaceutical composition is scientific and simple.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a composition capable of simultaneously lowering blood sugar and blood fat and a preparation method thereof. Background technique [0002] In recent years, high blood sugar, high blood fat, and high blood pressure have gradually become the three major killers that threaten human health, and they are showing a younger trend, which has seriously affected people's quality of life. Most patients with hyperlipidemia also have symptoms of high blood pressure, which can easily lead to stroke and cardiovascular disease. If they cannot be prevented and treated early, the consequences will be very serious. [0003] Hyperlipidemia can be divided into two types: primary and secondary. Primary is congenital and hereditary, and is caused by abnormalities in receptors, enzymes, or apolipoproteins involved in lipoprotein transport and metabolism due to single or polygenic defects, or due to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/605A61K9/48A61P3/06A61P3/10A61K33/24
CPCA61K36/48A61K36/605A61K36/28A61K36/42A61K36/064A61K33/24A61P3/06A61P3/10A61K9/1652A61K9/1635A61K2300/00
Inventor 朱志铭赵大鹏王杰李丽丽王光路李鹏
Owner HEBEI YUZHILIN PHARMA
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