Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Clostridium composition with weight-losing and lipid-lowering functions and preparation method thereof

A Clostridium and composition technology, applied in the field of microbial preparations, can solve the problems of reducing lipid absorption, etc., and achieve the effects of reducing lipid absorption, weight loss, lowering cholesterol, and improving intestinal function

Inactive Publication Date: 2021-09-21
深圳市巨印科技有限公司
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a control, the research team also conducted experiments on germ-free mice. The study found that the germ-free mice with the deletion of the Myd88 gene also reduced lipid absorption with the help of Clostridia, became "slender", and desulfurized Vibrio inhibits this effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Clostridium composition with weight-losing and lipid-lowering functions and preparation method thereof
  • Clostridium composition with weight-losing and lipid-lowering functions and preparation method thereof
  • Clostridium composition with weight-losing and lipid-lowering functions and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0039] According to another embodiment of the present invention, such as figure 1Shown, also provide the preparation method of the clostridium composition with fat-reducing functions for weight loss, the method comprises the following steps:

[0040] S1. Obtain two kinds of fermentation liquids by culturing caproic acid-producing Clostridium and Clostridium butyricum through seed culture and fermentation culture respectively;

[0041] S2. Centrifuge the fermented bacteria liquid and collect the bacteria sludge respectively, freeze-dry and pulverize the bacteria sludge to obtain two kinds of bacteria powder;

[0042] S3. Mixing the two bacterial powders with the bacterial powder carrier according to the ratio of parts by mass to obtain a mixture;

[0043] S4. Weighing red sage root, bilberry, black fruit wolfberry and purple sweet potato according to the ratio of parts by mass, soaking, sterilizing and drying to obtain dry powder;

[0044] S5. Obtaining oligopeptide 1 and oli...

Embodiment 1

[0061] The Clostridium composition prepared by the present invention and comparative example (select conventional probiotic composition) are carried out animal experiment, experimental process is as follows:

[0062] Select SD rats (body weight 200~220g) 40, divide into blank group, model group, composition group, contrast group at random according to body weight, each group has 10; Except blank group, all the other three groups are given modeling feed ( Basic feed 39%, lard 23%, sucrose 21%, egg yolk powder 9%, salt 8%); The blank group was given common feed, all 25g / bird / day, supplemented with common feed after eating, and each group had unlimited drinking water.

[0063] Among them, the composition group was given 0.3 g / kg body weight d of the Clostridium composition prepared by the present invention, the control group was given 0.3 g / kg body weight d of the conventional probiotic composition, and the blank group and the model group were given equal volumes of distilled wate...

Embodiment 2

[0076] Choose the clostridia composition prepared by the present invention and comparative example (select conventional probiotic composition) to carry out human trial detection effect, experiment is as follows:

[0077] Test object: choose 20 volunteers, be divided into contrast group and experiment group, each group is 10 volunteers, the age is 23~45 years old, and experiment group volunteer uses composition of the present invention to smear evenly near navel every day, every day Once a day, apply continuously for 2 months; the control group uses conventional probiotic composition to apply evenly near the navel, once a day, apply continuously for 2 months.

[0078] Judging criteria: obvious: the weight loss is obvious, and the complexion is obviously improved; general: the weight is decreased, and the complexion is improved; invalid: the weight is not decreased or increased, and the complexion is not improved; diarrhea.

[0079] The experimental results are as follows:

[...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a clostridium composition with weight-losing and lipid-lowering functions and a preparation method thereof. The composition for losing weight and lowering lipid is prepared from the following raw materials in parts by mass: 5 to 8 parts of clostridium powder for producing hexanoic acid, 7 to 15 parts of clostridium butyricum powder, 0.01 part of oligopeptide I, 0.005 part of oligopeptide II, 2 to 5 parts of red sage root extract, 2 to 5 parts of vaccinium uliginosum extract, 2 to 5 parts of lycium ruthenicum extract, 2 to 5 parts of purple sweet potato, 15 to 20 parts of psyllium husk, 50 to 90 parts of medicinal corn starch and 7 to 11 parts of silicon dioxide. The composition has the beneficial effects that the lipid absorption can be reduced and the intestinal function can be improved under the action of the clostridium for producing hexanoic acid and clostridium butyricum; the oligopeptide I and the oligopeptide II are bioactive peptides, can inhibit adipogenesis, and have remarkable effects of losing weight and reducing cholesterol; the red sage root, the vaccinium uliginosum, the lycium ruthenicum and the purple sweet potato extract contain a lipase inhibitor and can reduce blood fat.

Description

technical field [0001] The invention relates to the technical field of microbial preparations, in particular to a Clostridium composition with functions of weight loss and fat reduction and a preparation method thereof. Background technique [0002] With the acceleration of industrialization and urbanization in various countries, the obesity rate in many countries in the world is showing an increasing trend year by year. The disease burden of obesity is impacting the medical and health system, and then gradually spread to all levels of society, economy, and culture. A comprehensive proposition. In 2015, there were about 603.7 million obese adults worldwide, and the prevalence of obesity was 12%. The 2002 "Nutrition and Health Survey of Chinese Residents" data is in accordance with the "Guidelines for the Prevention and Control of Overweight and Obesity in Chinese Adults" standard. The overweight rate of Chinese adults is 22.8%, and the obesity rate is 7.1%. The prevalence ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A23L33/135A23L33/18A23L33/105A23L19/10
CPCA23L33/135A23L33/18A23L33/105A23L19/105A23V2002/00A23V2200/332A23V2200/3262A23V2250/21A23V2250/2106A23V2250/55A23V2250/5118A23V2250/1628
Inventor 魏晶
Owner 深圳市巨印科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com