Purpose of oxytocin or derivative thereof in preparation of preparation used for treating or eliminating flat chest, and composition

A technology of oxytocin and composition, applied in the field of pharmacology, can solve the problems of breast lump, endocrine disorder, transient and the like

Active Publication Date: 2021-08-20
穆琳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with the increase of age or after pregnancy, the skin loses vitality due to poor Qi and blood, which will accelerate aging, the breasts are prone to sagging, and the skin is loose, leading to endocrine disorders; estrogen secretion decreases, breast nutrition supply is insufficient, and then Cause breast dysplasia, rough skin
Moreover, under the fast-paced and high-stress life rhythm, irregular diet and bad emotions, breast diseases are prone to occur, which affects the health of the breast, thereby inducing breast hyperplasia and breast lumps, which has caused great distress to the majority of women.
[0007] At present, there are a large number of wet pleura, mask ointment, nursing solution, etc. used for breast care on the market, but most of the existing products for treating anemia only contain a single active ingredient for treating anemia, and the treatment effect is not good; or lack The scientific cognition of breast tissue dysplasia, premature aging and relaxation, and blindly adding a variety of breast enhancement ingredients, resulting in little breast enhancement effect
In addition, in order to achieve short-term breast enhancement, some breast enhancement products add a variety of potentially harmful ingredients, such as large doses of hormones, causing adverse reactions such as itching, redness, heat, and peeling on the skin of consumers

Method used

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  • Purpose of oxytocin or derivative thereof in preparation of preparation used for treating or eliminating flat chest, and composition
  • Purpose of oxytocin or derivative thereof in preparation of preparation used for treating or eliminating flat chest, and composition
  • Purpose of oxytocin or derivative thereof in preparation of preparation used for treating or eliminating flat chest, and composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Weigh 6mg of oxytocin, 0.6mL of lavender essential oil, and mix with 30mL of 0.9% normal saline to obtain composition A. When in use, the composition A is placed in a nasal spray bottle, enters the nasal cavity in the form of aerosol, and is sprayed once in each of the left and right nostrils, and the dosage for one nostril is 0.1 mL.

Embodiment 2

[0029] Weigh 3mg of oxytocin, 0.3mL of lavender essential oil, and mix them evenly with 30mL of 0.9% normal saline to obtain composition B. Refer to Example 1 for usage.

Embodiment 3

[0031] Weigh 3 mg of carbetocin, 0.3 mL of lavender essential oil, and mix evenly with 30 mL of 0.9% normal saline to obtain composition C. Refer to Example 1 for usage.

[0032] 2. Efficacy test of human breast enlargement:

[0033]Select 75 female volunteers with poor breasts who are healthy and without other diseases, aged between 20 and 40 years old, who have not undergone any breast enhancement treatment within two months, and are randomly divided into 5 groups, 15 people in each group. The five groups are respectively Example 1 group (using the composition A of Example 1), Example 3 group (using the composition C of Example 3), oxytocin+normal saline group, lavender essential oil+normal saline group , normal saline group; The reagent components used by the remaining three groups outside the embodiment 1 and 3 groups are as follows:

[0034] Oxytocin + normal saline group: accurately weigh 6 mg of oxytocin and mix it with 30 mL of 0.9% normal saline;

[0035] Lavender ...

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PUM

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Abstract

The invention discloses a purpose of oxytocin or a derivative thereof in preparation of a preparation used for treating or eliminating the flat chest, and a composition. The invention takes the oxytocin and an analogue or the derivative thereof as effective ingredients for treating the flat chest symptom, discusses and verifies that the oxytocin and the analogue or the derivative can effectively treat the flat chest to a certain degree, and also can provide an effective method for treating postpartum sagging breasts. The invention further discovers that Lavandula angustifolia Mill. essential oil and the oxytocin can be jointly utilized to generate a synergistic effect, i.e., an effect generated by joint utilization is better than the sum of the effects of single ingredient in individual utilization so as to speculate that the Lavandula angustifolia Mill. essential oil can perform the functions of soothing the nerves and assisting in sleep, and deep sleep can accelerate protein synthesis and the secretion function of the gland so as to improve a flat chest treatment effect.

Description

technical field [0001] The invention belongs to the technical field of pharmacology, and relates to the use and composition of oxytocin or its derivatives in preparing preparations for treating or improving poor milk. Background technique [0002] Oxytocin (Oxytocin) is one of the first polypeptide hormones to be isolated and sequenced. It is a nonapeptide and contains two cysteine ​​residues, forming a disulfide bond between the 1 and 6 positions. Its molecular formula is: NH 2 -Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-CONH 2 , the polypeptide is synthesized by the hypothalamus, stored in the posterior pituitary gland, and released when needed, stimulating certain smooth muscle cells, constricting certain blood vessels and increasing the sensitivity of other hormones and nerves, that is, allowing the effect. The hormone has a short survival period in the body and has a rapid onset of action. The tissues that can act include: uterus, vagina, breast, seminal vesicles and corpus ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/095A61K36/53A61K9/00A61K9/12A61K9/70A61P15/14
CPCA61K38/095A61K36/53A61K9/0043A61K9/006A61K9/12A61K9/7023A61P15/14A61K2300/00
Inventor 穆琳
Owner 穆琳
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