Mask-type breath sampler and breath test mask

Abstract

The present disclosure provides a mask-type respiration sampler and a respiration test mask. The mask-type respiration sampler includes a base and a first sampling device, a second sampling device and a third sampling device arranged in the base. The base includes a breather Air inlet and exhalation outlet, the inlet of the first sampling device is communicated with the exhalation inlet, and the first sampling device is used to collect the first exhaled sample; the inlet of the second sampling device is communicated with the outlet of the first sampling device, and the second sampling device The outlet of the device is communicated with the exhalation outlet, and the second sampling device is used to collect the second exhaled sample; the inlet of the third sampling device is communicated with the external environment, the outlet of the third sampling device is communicated with the exhalation outlet, and the third sampling device is used for It is used to collect gas samples from the external environment. The present disclosure can realize synchronous sampling of different samples, improve the accuracy of analyzing samples, the sampler has a simple structure, can realize sample enrichment in the sampling process of breath samples, and save sample preprocessing time.

Description

technical field [0001] The present disclosure relates to the field of metabolome sampling, and in particular, to a mask-type breath sampler and a breath test mask. Background technique [0002] In metabolomics research, there are certain differences in the sampling methods due to different sources of metabolic samples. By comparing the sampling methods of samples in different metabolomes, it can be seen that exhaled metabolomics studies have the advantage of continuous sampling. The gas-blood barrier of the organism is semi-permeable, and the gas-liquid exchange area, water vapor evaporation and pneumatic atomization of the liquid film on the inner surface of the lower respiratory tract (bronchioles, respiratory bronchioles, alveolar ducts, etc.) during respiration are considerable, and exhalation The metabolome not only reflects the metabolism of relevant tissues mainly in the lungs, but also reflects secondary and systemic metabolism by presenting metabolites in the blood...

AI Technical Summary

Problems solved by technology

[0003] At present, air sampling bag is the most commonly used offline breath sampling medium, but limited by the limited volume of the air sampling bag and the low concentration of exhaled metabolites, it is not convenient to use this traditional sampling method for subsequent detection of exhaled metabolites , the sample pretreatment takes a long time, and the sensitivity of the actual detection is low

Ambient air itself can directly interfere with breath samples, and inhalation exposure can also indirectly affect breath metabolism, so traditional sampling methods will affect the analytical sensitivity and accuracy of breath samples

In addition, there is still a lack of simultaneous sampling of breath samples and ambient air samples

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