Vagina pH regulator as well as preparation method and application thereof

Abstract

The invention relates to the technical field of medicines, and discloses a vagina pH regulator as well as a preparation method and application thereof. The vagina pH regulator contains glucose, urea, potassium hydroxide, carbomer, glycerol, lactic acid, citric acid, tartaric acid, a preservative and water. The vagina pH regulator disclosed by the invention can regulate the vagina pH value to be in a normal range of 3.5-4.5, resist and inhibit the growth of pathogenic bacteria, maintain the microbial environment health in the vagina, and effectively regulate the pH value even in the presence of seminal fluid. Therefore, an acidic environment which is not suitable for the survival of sperms and viruses and bacterial pathogens related to sexual transmission infection but is essential for the survival of healthy bacteria in the vagina is maintained.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a vaginal pH regulator and its preparation method and application. Background technique [0002] Vaginal fluid is composed of plasma exudate from the vaginal wall, glandular secretions, cervical mucus, endometrium and fallopian tube fluid, residual urine and exfoliated epithelial cells, etc. The characteristics and composition of this fluid largely determine Interactions between the microbiota and urogenital pathogens. Vaginal fluid contains water organic matter and inorganic salts, urea, carbohydrates, mucin, fatty acids, albumin, immunoglobulin and other macromolecules. The carbohydrates of vaginal fluid contain a small amount of mannose and glucose in addition to the main glucose Amines, organic acids, in addition to the main lactic acid and acetic acid, also contain a small amount of formic acid, succinic acid, propionic acid, butyric acid and sodium, potassium, chloride, c...

AI Technical Summary

Problems solved by technology

[0003] Affected by age, pregnancy and external factors, the microbial flora in the vagina of women changes, the cleanliness and pH of the vagina change, and the vaginal flora is out of balance, which leads to vaginal inflammation; or due to certain factors, the level of estrogen decreases, epithelial cells The reduction of glycogen content in the vagina leads to the reduction of lactic acid production, which increases the pH of the vagina. When the pH value in the vagina is greater than 5.0, the growth and reproduction of lactobacilli in the vagina are inhibited, which eventually leads to the invasion and reproduction of bacteria, which in turn leads to inflammation; After life, in the presence of semen in the vagina (semen usually raises the pH of the vagina to 7.0-8.0), healthy bacteria lose their dominance, leading to the invasion of certain viral and bacterial pathogens associated with sexually transmitted infections, which in turn cause a series of diseases

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