System for assessing ovarian reserve function of subject

An ovarian reserve and subject technology, applied in biological testing, material testing products, medical automated diagnosis, etc., can solve the problems of difficult, resource-consuming, time-consuming and other problems of reliable AFC assessment, so as to reduce testing costs, be easy to accept, and solve Poor repeatability

Pending Publication Date: 2021-06-04
PEKING UNIV THIRD HOSPITAL +1
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Problems solved by technology

However, obtaining good AFC results requires ultrasonography by skilled transvaginal sonography (TVS) specialists, which is time- and resource-intensive
Lack of standards in AFC measurement, AFC changes with menstrual cycle, contraceptive use, and TVS device sensitivity and resolution, all existing confounding factors can make reliable assessment of AFC more difficult

Method used

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  • System for assessing ovarian reserve function of subject
  • System for assessing ovarian reserve function of subject

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Experimental program
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Embodiment

[0157] Inclusion criteria were: women aged 20 to 45 years, body mass index (BMI) ≤ 30, six consecutive menstrual cycles of 25 to 45 days, normal bilateral ovarian morphology assessed by vaginal ultrasonography, previous IVF / ICSI- ET cycle number ≤ 2.

[0158] The exclusion criteria were: hydrosalpinx, unilateral ovary AFC>20, polycystic ovary syndrome, other untreated metabolic or endocrine diseases, previous surgery for the ovary or uterine cavity, intrauterine abnormalities, pregnancy within 3 months, Smoking, using oral contraceptives or other hormones within the previous two months, having previously undergone radiation or chemotherapy, undergoing PGD (preimplantation genetic diagnosis) / PGS (preimplantation genetic screening) Diagnosed couple.

[0159] Controlled Ovarian Stimulation (COS) Therapy

[0160] Gn (ie, human recombinant FSH) treatment was started on day 2 or day 3 of the menstrual cycle. The starting dose is based on age, BMI (body mass index, which is the nu...

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Abstract

The invention relates to a system for optimally evaluating the reserve function and ovarian adolescence of a subject. The system comprises a data acquisition module for acquiring the data of the age and the anti-mullerian hormone (AMH) level of the subject; and an ovarian reserve function or adolescence calculation module, which is used for calculating the information acquired in the data acquisition module so as to calculate the probability (p) of the low ovarian response of the subject, obtain an adolescence score and evaluate the ovarian adolescence according to the adolescence score.

Description

technical field [0001] The present invention relates to a system and method for evaluating the ovarian reserve function of a subject and the level of ovarian youth (referred to as youth) of the subject. The system or method can be used to evaluate the subject's own ovarian reserve function or affected The ovarian youth level of the test subjects is used to assess their fertility potential, and to assess whether the fertility potential of the subjects has improved after corresponding treatment. Background technique [0002] The number of primordial follicles contained in the ovarian cortex is called the ovarian reserve. It reflects the ability of the ovary to provide healthy eggs that can be fertilized successfully, and is the most important evaluation index of female ovarian function. Generally speaking, the greater the number of primordial follicles, the better the quality and the higher the chance of conception. [0003] Ovarian reserve increases and gradually depletes w...

Claims

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Application Information

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IPC IPC(8): G16H50/20G01N33/74
CPCG16H50/20G01N33/74
Inventor 徐慧玉李蓉乔杰冯国双韩勇
Owner PEKING UNIV THIRD HOSPITAL
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