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A detection reagent storage device for detecting braf gene mutation

A storage device and detection reagent technology, which is applied in the directions of transportation and packaging, types of packaging items, special packaging items, etc., can solve the problems of thermal insulation efficiency and the difficulty of guaranteeing the effect, and the reagent tube cannot provide protection, etc., so as to improve the efficiency of liquid exchange and ensure Effectiveness, the effect of improving stability

Active Publication Date: 2022-07-08
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The BRAF gene is located on chromosome 7 and is an oncogene. Among them, V600E is the most mutated site in the BRAF gene, which is often found in melanoma, non-Hodgkin's lymphoma, colorectal cancer, thyroid cancer, non-small cell Mutations in lung cancer are currently most commonly used in the auxiliary diagnosis of thyroid cancer. Corresponding detection reagents are required for genetic testing, and the reagents need to be stored for use. At present, the storage of reagents is often placed directly in a refrigerator. The insulation efficiency and effect are difficult to guarantee, and the reagent tube cannot be protected during transportation

Method used

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  • A detection reagent storage device for detecting braf gene mutation
  • A detection reagent storage device for detecting braf gene mutation
  • A detection reagent storage device for detecting braf gene mutation

Examples

Experimental program
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Embodiment Construction

[0025] see Figures 1 to 4 In the embodiment of the present invention, a storage device for detecting BRAF gene mutation detection reagent includes a storage tank 1, a circulation pipeline 2, a refrigeration bin 3, a circulation pump 4, a liquid exchange and cooling component 5, and a reagent tube placement component 7, wherein , a circulation pipe 2 is fixedly arranged under the interior of the storage box 1, and the circulation pipe 2 includes an upper horizontal pipe and a lower horizontal pipe, wherein the lower horizontal pipe is embedded and connected with a refrigerating bin 3, and the inner part of the circulation pipe 2 is connected. The cooling liquid is driven by the circulating pump 4 for circulating flow;

[0026] In the upper horizontal pipe, at least two groups of liquid exchange and cooling supply assemblies 5 are sequentially connected along the flow direction of the cooling liquid. The placing component 7 is used for placing the reagent tubes, and the coolin...

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Abstract

The invention discloses a reagent storage device for detecting BRAF gene mutation. In the invention, the cooling liquid is used as the temperature maintaining medium of the reagent tube, which can effectively improve the temperature maintaining stability of the reagent tube. The cooling liquid in the liquid exchange and cooling components is monitored in real time. When the liquid is exchanged synchronously, the cooling liquid in the circulating pipeline can be supplemented into the liquid exchange tank by the suction of the micro suction pump, and the Part of the cooling liquid in the liquid exchange tank is discharged, so that the cooling capacity of the cooling liquid in the liquid exchange tank can be smoothly improved to reach the initial level. Push the push plate to move, the push plate can push out the liquid in the liquid exchange tank, and the distance between the top of the push plate and the top of the liquid exchange tank can ensure that the push plate is automatically reset after the liquid exchange is completed, which improves the liquid exchange rate. Efficiency ensures the effectiveness of the reagents, thereby ensuring the accuracy of the detection.

Description

technical field [0001] The invention relates to the technical field of reagent storage, in particular to a reagent storage device for detecting BRAF gene mutation. Background technique [0002] The BRAF gene is located on chromosome 7 and is an oncogene. Among them, V600E is the most easily mutated locus in the BRAF gene, which is often found in melanoma, non-Hodgkin's lymphoma, colorectal cancer, thyroid cancer, non-small cell Mutations in lung cancer are most commonly used in the auxiliary diagnosis of thyroid cancer. Corresponding detection reagents need to be used in genetic testing, and the reagents need to be stored and used. At present, the storage of reagents is often directly placed in the refrigerator. The thermal insulation efficiency and effect are difficult to guarantee, and the reagent tubes cannot be protected during transportation. [0003] Therefore, it is necessary to provide a storage device for detecting BRAF gene mutation detection reagents to solve the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B65D25/02B65D81/18B65D81/05
CPCB65D25/02B65D81/18B65D81/05
Inventor 王萍付浴东于清邓玉杰王青
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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