A traditional Chinese medicine composition for preventing and treating recurrent miscarriage

A technology for recurrent miscarriage and composition, which is applied in the direction of drug combination, disease, and medical formula, which can solve the problems of many side effects and poor curative effect, and achieve the effect of simple preparation method, high safety, and improved clinical curative effect

Active Publication Date: 2022-05-10
SHENZHEN MATERNITY & CHILD HEALTHCARE HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, anticoagulant therapy is only effective for some patients, with poor curative effect and many side effects

Method used

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  • A traditional Chinese medicine composition for preventing and treating recurrent miscarriage
  • A traditional Chinese medicine composition for preventing and treating recurrent miscarriage
  • A traditional Chinese medicine composition for preventing and treating recurrent miscarriage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Preparation of decoction:

[0019] Recipe: Cuscuta 30g, Sangji 15g, Dipsacus 15g, Fried Puhuang 10g, Ginseng 10g, Tangerine Peel 10g, and Spatholobus 30g

[0020] Preparation method: take the Chinese medicinal decoction pieces in the formula and soak them in water for 0.5 h-1 h, then decoct them continuously for 3-5 times, combine the filtrates of each decoction, concentrate the combined filtrates to 1200 ml, and obtain the Chinese medicine composition decoction.

Embodiment 2

[0022] After concentrating the decoction prepared in Example 1 above, certain pharmaceutical excipients were added to prepare it into pills, tablets, capsules, granules and injections, respectively.

Embodiment 3

[0024] 1 Materials and methods

[0025] 1.1 Observation data

[0026] Part of the threatened miscarriage patients who were hospitalized in the Department of Traditional Chinese Medicine of Shenzhen Maternal and Child Health Hospital from March 2017 to December 2019 were included in the clinical trial, and a total of 138 patients with recurrent miscarriage caused by antiphospholipid syndrome of kidney deficiency and blood stasis type were included. Cases, aged between 25-48 years old, with an average age of 33.7 years; Among them, the number of spontaneous abortions in the past was 2-8 times, of which 82 cases had 2 spontaneous abortions, 37 cases had 3 times, and 19 cases had 4 or more times , the average number of miscarriages was 2.64 times. All the above-mentioned patients were randomly divided into observation group and control group. There was no statistically significant difference in baseline data such as age, number of pregnancies, and number of spontaneous abortions ...

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Abstract

The invention relates to the technical field of traditional Chinese medicine compounds, in particular to a traditional Chinese medicine composition for preventing and treating recurrent miscarriage. The described traditional Chinese medicine composition for preventing and treating recurrent miscarriage is made from the following medicinal raw materials: 25-35 parts of dodder, 10-20 parts of mulberry parasitoids, 10-20 parts of interrupted, 8-14 parts of fried Puhuang, 8 parts of ginseng -13 parts, 7-12 parts of dried tangerine peel, and 20-35 parts of Chixueteng, the traditional Chinese medicine composition has high safety, is convenient to improve the success rate of tocolysis, and can be combined with other drugs to improve clinical efficacy.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compound prescriptions, in particular to a traditional Chinese medicine composition for preventing and treating recurrent miscarriage. Background technique [0002] Spontaneous miscarriages that occur repeatedly in a couple are recurrent abortions (RSA). In my country, 3 or more fetal losses before 28 weeks of gestation are defined as RSA, and at the same time, it is suggested that 2 consecutive abortions should be paid attention to and evaluated. RSA is one of the most common pregnancy complications with an incidence rate of about 5% among women of childbearing age. The disease is most closely related to antiphospholipid syndrome (APS). [0003] The main clinical manifestations of antiphospholipid syndrome are recurrent miscarriage, arterial and venous thrombosis, and thrombocytopenia. anti-β2-GPⅠIgG). Therefore, the phospholipid antibody attacks the microcirculation bloo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61P15/00
CPCA61K36/39A61K36/43A61K36/185A61K36/88A61K36/258A61K36/752A61K36/486A61P15/06A61K2236/331A61K2236/53A61K2236/51A61K2300/00
Inventor 宁艳马飞何珊
Owner SHENZHEN MATERNITY & CHILD HEALTHCARE HOSPITAL
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