Gallstone pharmaceutical preparation and preparation method thereof

A technology for gallstones and medicines, applied in the field of gallstone pharmaceutical preparations and its preparation, can solve the problems of poor stone expulsion effect, secondary infection, etc., and achieve the effect of short course of treatment, promotion of absorption, and good effect of stone expulsion

Inactive Publication Date: 2021-04-09
BEIJING WANHUI DOUBLE CRANE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the improvement of social living standards and the acceleration of the pace of life, the incidence of cholecystitis and gallstone disease is on the rise, and most of them occur in middle-aged people aged 35-55. , "biliary distension", "jaundice" and other diseases, traditional Chinese medicine believes that its onset is caused by emotional disorders, improper diet, and endogenous accumulation of dampness and heat. The disease is mainly in the liver and gallbladder, involving the spleen and stomach. , large intestine, the main pathogenesis is liver and gallbladder disorder, damp-heat accumulation, disharmony between liver and stomach, poor bile excretion, blockage of gallstones, blockage of gallbladder and internal organs, and gallstones are formed by its pathological products. Gallstones, also known as cholelithiasis, refer to the Including gallstones in...

Method used

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preparation example Construction

[0021] A preparation method for gallstone pharmaceutical preparation, comprising the following steps:

[0022] S1, weighed by weight: 7-9 parts of Desmodium, 10-12 parts of Curcuma, 6-8 parts of Citrus aurantii, 6-8 parts of Radix Paeoniae Alba, 4-6 parts of Astragalus and 6-8 parts of Shiwei Add to the reaction kettle one by one, stir and mix, and add water according to the weight ratio of medicinal materials to water 1:4 and heat to 60-80°C for extraction for 0.8-1h, filter, and concentrate the filtrate to a 1:1 paste, that is, Chinese medicine combination extraction Material A, spare;

[0023] S2, weighed in parts by weight: 14-16 parts of azinamide, 10-12 parts of pancreatin, respectively, at room temperature, 14-16 parts of azinamide, 10-12 parts of pancreatin, and dimethyl Add 6-8 parts of silicone oil to the Chinese medicine combination extract obtained in S1, stir and mix to obtain a viscous substance B;

[0024] S3, dripping pills: Add 30-40 parts of simethicone int...

Embodiment 1

[0039] Step 1, weighed respectively by weight: 8 parts of Desmodium, 11 parts of Curcuma, 7 parts of Citrus aurantium, 7 parts of Radix Paeoniae Alba, 8 parts of Radix Astragali and 7 parts of Shiwei were added to the reaction kettle in turn, and the stirring speed was 400~500r / min, stir and mix, and add water according to the weight ratio of medicinal materials to water 1:4 and heat to 60~80°C for 0.8~1h, and filter through 400~600 mesh filter cloth, and the filtrate is concentrated to 1:1 Paste, that is, Chinese medicine combination extract A, for use;

[0040] Step 2, weighing by weight: 14 parts of azinamide and 10 parts of trypsin, at 22-24°C, add 14 parts of azinamide and 10 parts of trypsin to the obtained in step 1 For the extract of traditional Chinese medicine combination, stir and mix at a speed of 300-400r / min, and keep stirring for 30-40min, and stir and mix to obtain viscous substance B;

[0041] Step 3, dripping pills: Add 40 parts of simethicone into the dripp...

Embodiment 2

[0044] Step 1, weighed respectively by weight: 8 parts of Desmodium, 11 parts of Curcuma, 7 parts of Citrus aurantium, 7 parts of Radix Paeoniae Alba, 8 parts of Radix Astragali and 7 parts of Shiwei were added to the reaction kettle in turn, and the stirring speed was 400~500r / min, stir and mix, and add water according to the weight ratio of medicinal materials to water 1:4 and heat to 60~80°C for 0.8~1h, and filter through 400~600 mesh filter cloth, and the filtrate is concentrated to 1:1 Paste, that is, Chinese medicine combination extract A, for use;

[0045] Step 2, weighing by weight: 15 parts of azinamide and 11 parts of trypsin, at 22-24°C, add 15 parts of azinamide and 11 parts of trypsin respectively to the obtained in step 1 For the extract of Chinese medicine combination, the mixing speed is 300-400r / min, and the stirring is continued for 30-40min, and the viscous substance B is obtained;

[0046] Step 3, dripping pills: Add 40 parts of simethicone into the drippi...

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Abstract

The invention relates to the technical field of pharmaceutical preparations, and particularly relates to a gallstone pharmaceutical preparation. The gallstone pharmaceutical preparation is prepared from azimi, pancreatin, dimethicone, herba lysimachiae, radix curcumae, fructus aurantii, radix paeoniae alba, radix astragali seu hedysari and folium pyrrosiae. According to the gallstone pharmaceutical preparation disclosed by the invention, the azimi which is a cholagogic drug is adopted as a main drug, and the azimi is a drug which is mainly used for promoting bile secretion; a compound fixed-formulation preparation is formed by the azimi, the pancreatin, the dimethicone and a traditional Chinese medicine composition for treating gallstone, and the compound fixed-formulation preparation can be used for promoting excretion of bile, promoting absorption and digestion of fat food and the like for patients with insufficient bile secretion and dyspepsia; and the dimethicone is also contained and can perform certain intervention for excessive gas, and a better effect is obtained for the patients with the insufficient bile secretion and the dyspepsia, so that the effects of reasonable formula, liver soothing, choleresis increasing, Qi promoting and pain relieving, good gallstone removing effect on treatment of gallstone in a liver and gall inner tube and gallstone diseases and quick effect are achieved.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a gallstone pharmaceutical preparation and a preparation method thereof. Background technique [0002] With the improvement of social living standards and the acceleration of the pace of life, the incidence of cholecystitis and gallstone disease is on the rise, and most of them occur in middle-aged people aged 35-55. , "biliary distension", "jaundice" and other diseases, traditional Chinese medicine believes that the onset is caused by emotional disorders, improper diet, and endogenous accumulation of dampness and heat. The disease is mainly in the liver and gallbladder, involving the spleen and stomach. , large intestine, the main pathogenesis is liver and gallbladder disorder, damp-heat accumulation, disharmony between liver and stomach, poor bile excretion, blockage of gallstones, blockage of gallbladder and internal organs, and gallstones are formed by its...

Claims

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Application Information

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IPC IPC(8): A61K38/43A61K47/34A61P1/16A61K31/50A61K36/9066
CPCA61K31/50A61K38/43A61K36/185A61K36/53A61K36/9066A61K36/752A61K36/71A61K36/65A61K36/481A61K36/12A61K47/34A61P1/16A61K2236/331A61K2236/51A61K2236/53
Inventor 曲民春陈利敏王义波艾俊丽田麒宋芙钟皓白艳娇孟晓雪王瑾孙国栋
Owner BEIJING WANHUI DOUBLE CRANE PHARMA
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