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Traditional Chinese medicine composition for treating ulcerative colitis and preparation method of traditional Chinese medicine composition

A technology for ulcerative colitis and a composition is applied in the field of traditional Chinese medicine compositions for the treatment of ulcerative colitis and the field of preparation thereof, which can solve the problems of mixed cold and heat, obvious side effects, high recurrence rate, prolong survival time, improve life quality, Alleviating the pain of disease

Inactive Publication Date: 2021-01-08
DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to solve the defects such as poor curative effect, high recurrence rate and obvious side effects of medicines for treating ulcerative colitis (especially severe ulcerative colitis and refractory ulcerative colitis) in the prior art, the present invention treats ulcerative colitis (especially severe ulcerative colitis and refractory ulcerative colitis), after long-term clinical observation and practice, it was found that the pathogenesis is based on spleen and kidney yang deficiency, and intestinal dampness and heat as the standard. The key to pathogenesis is mixed cold and heat, damp heat stasis

Method used

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  • Traditional Chinese medicine composition for treating ulcerative colitis and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating ulcerative colitis and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating ulcerative colitis and preparation method of traditional Chinese medicine composition

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Embodiment 1

[0039] Embodiment 1: A kind of Chinese medicine composition for the treatment of ulcerative colitis

[0040] 1. Composition: 12 parts of ebony plum, 6 parts of coptis, 10 parts of Phellodendron cortex, 3 parts of Asarum, 9 parts of Zanthoxylum bungeanum, 9 parts of Paojiang, 10 parts of Guizhi, 10 parts of Zhifu tablets, 6 parts of woody fragrance, 9 parts of Sophora flavescens , 3 parts of Qingdai, 6 parts of Panax notoginseng, 15 parts of Burnet charcoal, 15 parts of Pulsatilla, 10 parts of Qinpi and 6 parts of roasted licorice.

[0041] 2. Preparation method: mix the ingredients evenly according to the ratio, decoct with water equivalent to 10 times the weight of the medicinal materials for 2 hours, then decoct with water equivalent to 8 times the weight of the medicinal materials for 1.5 hours, filter, and concentrate the filtrate at 60°C To the extract whose relative density is 1.2-1.25.

Embodiment 2

[0042] Embodiment 2: a kind of Chinese medicine composition for the treatment of ulcerative colitis

[0043] 1. Composition: 11 parts of black plum, 7 parts of coptis, 9 parts of Phellodendron, 3 parts of Asarum, 9 parts of Zanthoxylum bungeanum, 8 parts of Paojiang, 11 parts of Guizhi, 9 parts of Zhifu tablets, 7 parts of woody fragrance, 8 parts of Sophora flavescens , 2 parts of Qingdai, 6 parts of Panax notoginseng, 15 parts of Burnet charcoal, 15 parts of Pulsatilla, 10 parts of Qinpi and 7 parts of roasted licorice.

[0044] 2. Preparation method: each component is crushed into fine powder, mixed evenly according to the proportion, and passed through a 100-150 mesh sieve.

Embodiment 3

[0045] Embodiment 3: a kind of Chinese medicine composition for the treatment of ulcerative colitis

[0046] 1. Composition: 13 parts of ebony plum, 5 parts of coptis, 10 parts of Phellodendron cortex, 2 parts of Asarum, 9 parts of Zanthoxylum bungeanum, 8 parts of Paojiang, 10 parts of Guizhi, 9 parts of Zhifu tablets, 6 parts of woody fragrance, 8 parts of Sophora flavescens , 4 parts of Qingdai, 6 parts of Panax notoginseng, 14 parts of Burnet charcoal, 15 parts of Pulsatilla chinensis, 11 parts of Qinpi and 6 parts of roasted licorice.

[0047] 2. Preparation method: mix the ingredients uniformly according to the proportion, pulverize into coarse powder, impregnate with 60% ethanol equivalent to 8 times the weight of medicinal materials for 30 hours, heat the medicinal solution to 35°C, force circulation for 3.5 hours, and filter.

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Abstract

The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating ulcerative colitis and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition consists of the following components: dark plums, coptis chinensis, golden cypress, asarum, Chinese prickly ash, baked ginger, cassia twigs, radix aconiti lateralis preparata, elecampane, radix sophorae flavescentis, indigo naturalis, pseudo-ginseng, carbonized sanguisorba roots, Chinese pulsatilla roots, ash bark andhoney-fried licorice roots. The traditional Chinese medicine composition has a good effect of treating ulcerative colitis (especially severe ulcerative colitis and refractory ulcerative colitis), andis low in recurrence rate and not obvious in side effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating ulcerative colitis and a preparation method thereof. Background technique [0002] Ulcerative colitis (UC) is a chronic non-specific inflammatory disease of unknown etiology that mainly occurs in the colorectum, mainly affecting young and middle-aged people aged 15-40. Ulcerative colitis is a lifelong disease, and its clinical symptoms such as diarrhea, mucus pus and blood in the stool, and abdominal pain seriously affect the quality of life of patients. The incidence and prevalence of ulcerative colitis show an increasing trend year by year, and clinically severe ulcerative colitis is not uncommon. Usually, the use of glucocorticoids (hereinafter referred to as hormones) is the first-line treatment for severe ulcerative colitis, but more than 30% of patients are resistant to hormones, which is called refractory...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/00A61P1/04
CPCA61K36/736A61K36/718A61K36/756A61K36/268A61K36/758A61K36/9068A61K36/54A61K36/714A61K36/285A61K36/489A61K36/704A61K36/315A61K36/195A61K36/258A61K36/739A61K36/71A61K36/63A61K36/484A61P1/00A61P1/04A61K2236/331A61K2236/333A61K2236/51
Inventor 李军祥
Owner DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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