Feed premix for increasing intestinal tight junction protein expression and application thereof

Abstract

The invention relates to a feed premix for increasing intestinal tight junction protein expression and application thereof. The feed premix comprises the following components in parts by mass: 5-20 parts of potassium diformate, 10-30 parts of oat hulls, 10-20 parts of wild buckwheat and 3-65 parts of activated carbon. The feed premix is added into basic ration of piglets, and the piglets begin toeat from the weaning day and are used for reducing the diarrhea rate of the weaned piglets. Compared with the prior art, the feed premix disclosed by the invention has the advantages that the intestinal immunity of the piglets can be enhanced by increasing the intestinal tight junction protein expression and reducing the intestinal permeability, so that the diarrhea rate and other diseases are reduced, and rapid growth of the piglets is promoted.

Description

technical field [0001] The invention relates to the field of feed premix for piglets, in particular to a feed premix for increasing the expression of intestinal tight junction protein and application thereof. Background technique [0002] Diarrhea in piglets in the farrowing room of modern breed-scale farms is common at present. According to data survey, piglet diarrhea in farrowing rooms of some pig farms is very serious, and the mortality rate is as high as 80%. Pig farms of different scales have occurred in different growth stages of suckling piglets, which has brought significant economic losses to pig farms. [0003] The intestine is an important organ for animal digestion, absorption and immunity, and has a profound impact on the growth, development and health of pigs, so there is a saying that "raising pigs is raising the intestines". To ensure gut health, it is important to ensure that the gut mucosal barrier in pigs is intact and functional. [0004] However, due ...

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Problems solved by technology

[0004] However, due to stress in weaned piglets, the intestinal permeability often increases and the integrity of the intestinal tract decreases, which in turn increases the risk of harmful bacteria and toxins penetrating the intestinal tract into the blood and causing enterogenous infection, resulting in harmful The most direct manifestation is piglet diarrhea and other diseases, leading to malnutrition and lack of energy, which in turn hinders the growth of piglets

[0005] At present, antibiotics are generally used clinically to inhibit pathogenic bacteria and improve the immune protection ability of the body, so as to maintain the intestinal structure and the functions of various parts of the digestive system to control piglet diarrhea and other diseases. However, due to the long-term use of antibiotics, pathogenic microorganisms Drug resistance is a serious threat to human health and the environment on which humans depend

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