Hydrogel patch material fixed on edge of mask or medical goggles, preparation method and application thereof
A hydrogel patch and hydrogel technology, applied in the field of network hydrogel, can solve the problems of not being able to fully seal, the protective gear environment is wet, and the skin is damaged, and achieve good biocompatibility and biological Degradability, the effect of resolving streaks and local sealing, and improving wearing comfort
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Embodiment 1
[0051] To prepare a hydrogel with hygroscopicity, compression resistance and antibacterial properties, the specific steps are:
[0052] 1) Dissolve carboxymethyl chitosan in deionized water to form a 1.00 g / ml carboxymethyl chitosan solution.
[0053] 2) The nano-silver is added into deionized water to dissolve to form a 0.04g / ml nano-silver solution.
[0054] 3) Dissolving acrylic acid in deionized water to form a 2.00 g / ml acrylic acid solution;
[0055] 4) 20.00ml of acrylic acid solution in step (3) is mixed with 10.00ml of carboxymethyl chitosan solution obtained in step (1) and 0.625ml of nano silver solution obtained in step (2), and 0.25g of ferric chloride is added in the resulting mixed solution Mix with initiator ammonium persulfate 0.0025g, stir evenly, react at 40°C for 10h, the solution becomes elastic hydrogel, and forms PAA / CMCS double network hydrogel.
[0056] 5) The oxidized dextran was dissolved in deionized water to form a 10 g / ml oxidized dextran soluti...
Embodiment 2
[0062] A preparation method for preparing a hydrogel with moisture absorption, compression resistance and antibacterial properties, the specific steps are:
[0063] 1) Add carboxymethyl chitosan to deionized water to dissolve to form a 1.50 g / ml carboxymethyl chitosan solution;
[0064] 2) adding nano-silver to deionized water to dissolve to form a 0.05g / ml nano-silver solution;
[0065] 3) Dissolving acrylic acid in deionized water to form a 4.00 g / ml acrylic acid solution;
[0066] 4) 15.0ml of step (3) acrylic acid solution is mixed with 10.0ml of step 1) gained carboxymethyl chitosan solution and 0.9ml of step 2) gained nano-silver solution, and 0.375g of ferric chloride is added in the resulting mixed solution to trigger Ammonium persulfate 0.00375g, stir evenly, react at 40°C for 10h, the solution becomes elastic hydrogel, forming PAA / CMCS double network hydrogel;
[0067] 5) The oxidized dextran was dissolved in deionized water to form a 15.0 g / ml oxidized dextran sol...
Embodiment 3
[0073] A preparation method for preparing a hydrogel with moisture absorption, compression resistance and antibacterial properties, the specific steps are:
[0074] 1) Carboxymethyl chitosan was added into deionized water to dissolve to form a 2.50 g / ml carboxymethyl chitosan solution;
[0075] 2) adding nano-silver to deionized water to dissolve to form a 0.10g / ml nano-silver solution;
[0076] 3) Dissolving acrylic acid in deionized water to form a 4.60 g / ml acrylic acid solution;
[0077] 4) 22.0ml of step (3) acrylic acid solution is mixed with 10.0ml of step 1) gained carboxymethyl chitosan solution and 0.625ml of step 2) gained nano-silver solution, and 0.631g of ferric chloride is added in the resulting mixed solution to trigger Ammonium persulfate 0.00631g, stir evenly, react at 40°C for 10h, the solution becomes elastic hydrogel, forming PAA / CMCS double network hydrogel;
[0078] 5) The oxidized dextran is dissolved in deionized water to form a 18g / ml oxidized dextr...
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