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Compound hypoglycemic product and preparation method thereof

A technology for hypoglycemic products, applied in the field of medicine, can solve the problems of drug quality standard control, difficulty in clinical use, waste of medicinal materials, etc., and achieve the effect of low price, small side effects and good curative effect

Inactive Publication Date: 2020-11-10
HARBIN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This not only wastes medicinal materials, but also causes great difficulties to the quality standard control and clinical use of drugs.

Method used

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  • Compound hypoglycemic product and preparation method thereof
  • Compound hypoglycemic product and preparation method thereof
  • Compound hypoglycemic product and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The preparation of embodiment 1 compound hypoglycemic product (Xinjiaotai preparation)

[0020] (1) Weigh 18 parts by weight of Coptidis rhizome and 2 parts by weight of cinnamon, crush and mix the weighed Coptis chinensis and cinnamon, put them into a water extraction tank, soak them in 65 degree white wine for 12 hours to moisten and desorb, and the ratio of solid to liquid is 1:2;

[0021] (2) Heat 15 times of distilled water to 100°C, add it into the extraction tank containing Coptis cinnamon desorption powder, and filter and extract twice, each time for 5 minutes. Combine the extracts, concentrate to extract, dry under reduced pressure, and pulverize into 80-mesh powder for later use;

[0022] (3) Take the spare powder, carry out gradient mixing with an appropriate amount of dextrin (or soluble starch), granulate, and pack separately to obtain a compound hypoglycemic product.

Embodiment 2

[0023] Preparation of embodiment 2 compound hypoglycemic product (Xinjiaotai preparation)

[0024] (1) Weigh 18 parts by weight of Coptidis rhizome and 2 parts by weight of cinnamon, crush and mix the weighed Coptis chinensis and cinnamon, put them in a water extraction tank, soak them in 60-degree white wine for 10 hours to moisten and desorb, and the ratio of solid to liquid is 1:2;

[0025] (2) Heat 18 times distilled water to 100°C, add it to the extraction tank with Coptis cinnamon desorption powder, filter and extract twice, each time for 3 minutes, combine the extracts, concentrate to extract, dry under reduced pressure, and crush into 80 mesh powder, spare;

[0026] (3) Take the spare powder, carry out gradient mixing with an appropriate amount of dextrin (or soluble starch), granulate, and pack separately to obtain a compound hypoglycemic product.

Embodiment 3

[0027] Preparation of embodiment 3 compound hypoglycemic product (Xinjiaotai preparation)

[0028] (1) Weigh 16 parts by weight of Coptidis rhizome and 3 parts by weight of cinnamon, crush and mix the weighed Coptis chinensis and cinnamon, put them into a water extraction tank, soak them in 65 degree white wine for 12 hours to moisten and desorb, and the ratio of solid to liquid is 1:3;

[0029] (2) Heat 10 times of distilled water to 100°C, add it to the extraction tank with Coptis cinnamon desorption powder, filter and extract twice, each time for 5 minutes, combine the extracts, concentrate to extract, dry under reduced pressure, and crush into 80 mesh powder, spare;

[0030] (3) Take the spare powder, carry out gradient mixing with an appropriate amount of dextrin (or soluble starch), granulate, and pack separately to obtain a compound hypoglycemic product.

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Abstract

The invention discloses a compound hypoglycemic product and a preparation method thereof. The preparation method comprises the following steps: (1) weighing 15 to 20 parts by weight of coptis chinensis and 1 to 5 parts by weight of cinnamomum cassia, crushing and mixing the weighed coptis chinensis and cinnamomum cassia, putting into a water extraction tank, soaking with white spirit with 60 to 70degrees for 10 to 15 hours, moistening and desorbing according to a solid-liquid ratio of 1: (2 to 3) so as to obtain coptis chinensis and cinnamomum cassia desorption powder; (2) heating 10 to 20 times of distilled water to a temperature of 100 DEG C, pouring into the extraction tank with the coptis chinensis and cinnamomum cassia desorption powder, carrying out filtration extraction for twice for 3 to 10 min each time, merging extracting solution, concentrating into extract, and carrying out decompression drying and grinding to form 80-mesh powder for later use; and (3) taking the standby powder, carrying out gradient mixing by dextrin or soluble starch, granulating, and sub-packaging to obtain a solid product. The invention provides a pharmaceutical formula capable of effectively reducing blood sugar and blood fat and a preparation method by defining effective components in the Jiaotai pills and scientifically matching the effective components. The pharmaceutical formula has the advantages of small side effect, good curative effect and low price.

Description

technical field [0001] The invention relates to a pharmaceutical preparation and a preparation method thereof, in particular to a medicinal formulation for treating diabetes and a hypoglycemic preparation prepared therefrom. The invention belongs to the technical field of medicine. Background technique [0002] Diabetes Mellitus (DM) is a syndrome of carbohydrate, fat and protein metabolic disorders caused by relative or absolute lack of insulin and varying degrees of insulin resistance. Persistent hyperglycemia is its basic biochemical feature. The main clinical manifestations are polydipsia, polyuria, polyphagia, weight loss, fatigue, etc. In the late stage, kidney disease, neuropathy, suppurative infection, vascular disease, cardiovascular disease, retinal damage and other diseases are often complicated, and ketosis may occur in severe cases Acidosis is life-threatening. Diabetes is mainly diagnosed based on hyperglycemia and its symptoms ("three more and one less") ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P3/10A61P3/06
CPCA61K36/718A61K36/54A61P3/10A61P3/06A61K2236/333A61K2236/331A61K2236/39
Inventor 赵研蔡铁全刘影张永春李莹项莹
Owner HARBIN MEDICAL UNIVERSITY
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