Asymmetric hydrophobic polyolefin hollow fiber membrane, preparation method and application thereof

Abstract

The invention provides an asymmetric hydrophobic polyolefin hollow fiber membrane, a preparation method and application thereof. The hollow fiber membrane comprises a support layer and a separation layer, the separation layer comprises an outer surface, and the outer surface comprises a certain number of first holes with a certain aperture; due to the existence of the first holes, anesthetic gaseslike sevoflurane and remifentanil can penetrate through the hollow fiber membrane to enter the blood of a patient, and the patient can be kept in a calm state all the time in the operation process; meanwhile, the dosage of anesthetic in an operation is reduced, the operation cost is reduced, and secondary injury to a patient due to excessive anesthetic is avoided; besides, the hollow fiber membrane also has relatively long plasma permeation time, high tensile strength and elongation at break, meets the requirements of practical application, and is particularly suitable for application to thefields of oxygenation and gas-liquid separation of human blood containing anesthetic gas; in addition, the invention also provides a preparation method of the hollow fiber membrane, and the preparation method is rapid, effective, simple to operate and suitable for large-scale popularization.

Description

technical field [0001] The invention relates to the technical field of membrane materials, and more specifically relates to an asymmetric hydrophobic polyolefin hollow fiber membrane and its preparation method and application. Background technique [0002] In many applications in the fields of chemistry, biochemistry or medicine there is the problem of separating gaseous components from liquids or adding these components to liquids. For these gas exchange processes, membranes are increasingly being used as separation membranes between various liquids and fluids which adsorb or release gaseous components, from which gaseous components are separated or added to these liquids. The fluid here can be a gas or a liquid which contains or absorbs the gas component to be exchanged. Using such membranes, an exchange surface for gas exchange can be provided and direct contact between liquid and fluid can be avoided if necessary. [0003] An important medical application of membrane-b...

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Problems solved by technology

[0005] In order to relax the patient, for many medical operations, the patient must fall asleep; therefore, during the operation, it is desirable to add an anesthetic, that is, an anesthetic gas, to the breathing air to provide sedation to the patient; and due to the existing hollow fiber membrane The separation layer is a dense layer, and the outer surface of the separation layer has no holes, which makes it difficult for the anesthetic gas to enter the blood of the human body through the hollow fiber membrane; Inject excessive anesthetics into patients, but because these anesthetics are very expensive, excessive anesthetics will greatly increase the cost of surgery and increase the economic burden of patients; in addition, excessive anesthetics are also likely to cause secondary damage to the patient's physical and mental health; therefore how to The preparation of a hollow fiber membrane that not only allows anesthetic gas to pass through, but also has a high plasma permeation time and high mechanical properties is a current research hotspot.

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