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Composition for regulating and controlling epidermal micro-ecological balance and application thereof

A technology of ecological balance and composition, which is applied in the direction of drug combination, skin care preparations, medical preparations containing active ingredients, etc., can solve the problem of destroying the balance between probiotics and harmful bacteria, and achieve improvement of skin problems, excellent heat resistance Stability, long-term storage effect

Inactive Publication Date: 2020-10-30
上海科颜生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, excessive cleaning, external chemical and physical factors such as antibiotics, ultraviolet light, lack of nutrition, cold, stress, etc. will destroy the balance between probiotics, harmful bacteria, and invading bacteria

Method used

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  • Composition for regulating and controlling epidermal micro-ecological balance and application thereof
  • Composition for regulating and controlling epidermal micro-ecological balance and application thereof
  • Composition for regulating and controlling epidermal micro-ecological balance and application thereof

Examples

Experimental program
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preparation example Construction

[0035] In some embodiments, the preparation method of the organic solvent extract comprises the steps of:

[0036] Patchouli leaves are crushed and added to the extraction tank, mixed with organic solvents, soaked for 2 to 4 hours, heated to 85°C for reflux extraction for 2 to 4 hours, then the system is cooled to room temperature, left standing to separate layers, and filtered to obtain the upper layer The clear liquid is obtained by concentrating and drying.

[0037] In some preferred embodiments, the mixed organic solvent is a mixture of methanol and ethyl acetate.

[0038] Preferably, the volume ratio of methanol to ethyl acetate is 1.5:1.

[0039] Further preferably, the solid-liquid ratio of the patchouli leaves and the mixed organic solvent is 1g: (40-60ml).

[0040] Even more preferably, the solid-liquid ratio of the patchouli leaves and the mixed organic solvent is 1g:55ml.

[0041] In some embodiments, the preparation method of the lye extract comprises the steps ...

Embodiment 1

[0063] Example 1 : present embodiment provides a kind of composition regulating epidermal micro-ecological balance, and its preparation raw material, by weight, comprises

[0064]

[0065] The plankton extract was purchased from Xiamen Xulijin Biotechnology Co., Ltd.; the inulin / α-glucan oligosaccharides (both purchased from Shanghai Merrill Chemical Technology Co., Ltd.) were inulin and α-glucan A mixture of oligosaccharides, the weight ratio is 1:1; the patchouli leaf extract includes organic solvent extract and lye extract, the weight ratio is 1.8:1; the preparation method of the organic solvent extract includes the following step:

[0066] Patchouli leaves are crushed and added to the extraction tank, mixed with organic solvents, soaked for 2.5 hours, heated to 85°C for reflux extraction for 3 hours, then cooled to room temperature, allowed to stand for layers, filtered to obtain the supernatant, concentrated Serve dry. The mixed organic solvent is methanol and ethyl...

Embodiment 2

[0071] Example 2 : present embodiment provides a kind of composition regulating epidermal micro-ecological balance, and its preparation raw material, by weight, comprises

[0072]

[0073] The plankton extract was purchased from Xiamen Xulijin Biotechnology Co., Ltd.; the inulin / α-glucan oligosaccharides (both purchased from Shanghai Merrill Chemical Technology Co., Ltd.) were inulin and α-glucan A mixture of oligosaccharides, the weight ratio is 1:1; the patchouli leaf extract includes organic solvent extract and lye extract, the weight ratio is 1.8:1; the preparation method of the organic solvent extract includes the following step:

[0074] Patchouli leaves are crushed and added to the extraction tank, mixed with organic solvents, soaked for 2.5 hours, heated to 85°C for reflux extraction for 3 hours, then cooled to room temperature, allowed to stand for layers, filtered to obtain the supernatant, concentrated Serve dry. The mixed organic solvent is methanol and ethy...

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Abstract

The invention relates to the technical field of skin care products, in particular to a composition for regulating and controlling epidermal micro-ecological balance and application of the composition.The composition is prepared from the following raw materials in parts by weight: 20 parts of pogostemon cablin leaf extract, 20 parts of plankton extract, 35 parts of inulin / alpha-glucan oligosaccharide, 35 parts of butanediol and 10 parts of dipalmitoyl phosphatidylcholine. The composition provided by the invention can be used for effectively regulating and controlling a microbial ecological barrier on the skin surface; tree ages of probiotics and harmful bacteria on epidermis are effectively controlled, and the skin problems of excessive skin grease, coarse pores, a large amount of acnes, skin inflammation and the like caused by mass propagation of harmful bacteria on epidermis, change of epidermis micro-ecology and promotion of sebaceous gland to secrete a large amount of grease are avoided. And the skin problem of volunteers with a large amount of grease secreting vigorously is effectively improved. In addition, the composition provided by the invention also has excellent heat-resistant stability and cold-resistant stability, and can be stored and used for a long time in a harsh environment.

Description

technical field [0001] The present invention relates to the technical field of skin care products, in particular to a composition for regulating the micro-ecological balance of the epidermis and its application. Background technique [0002] The skin is the first physiological barrier of the human body. A healthy skin can resist external pollution, stimulation, damage and sunlight, and also has moisturizing and regulating functions. However, due to factors such as living environment, work and rest habits, and skin care methods, the skin barrier is easily damaged, which makes the skin's own defense ability insufficient, which in turn leads to a series of skin problems such as oily skin, enlarged pores, sensitivity, acne, inflammation, and aging. . [0003] In the process of the above-mentioned skin problems, the skin is always dealing with the probiotics and harmful bacteria on its surface, and interacts with each other. The dynamic balance of probiotics and harmful bacteri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9706A61K8/98A61K8/99A61K8/73A61K8/34A61K8/55A61Q17/00A61Q19/00A61P17/10A61P17/00
CPCA61K8/345A61K8/553A61K8/73A61K8/987A61K8/99A61K2800/592A61K2800/805A61Q17/005A61Q19/00A61Q19/008A61K8/9706A61K8/9789A61P17/00A61P17/10
Inventor 陈潇
Owner 上海科颜生物科技有限公司
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