Animal magnetic resonance imaging eye protection device and use method

Abstract

The invention provides an animal magnetic resonance imaging eye protection device and a use method. The eye protection device comprises two conical eyeshades, wherein the two conical eyeshades are provided with a connecting mechanism fixed to the head of an animal; cotton gauze is arranged in each conical eyeshade; the top of the conical eyeshade is provided with a pressure type nozzle facing thecotton gauze; the pressure type nozzle is connected with an air conveying assembly; the air conveying assembly comprises a first air conveying pipe; one end of the first air conveying pipe is connected with two second air conveying pipes, and the other end of the first air conveying pipe is connected with an air adding device; the second air conveying pipes are connected with the pressure type nozzles; and a water filling opening is formed in the first air conveying pipe. The eye protection device can be repeatedly used while preventing blindness of eyes of an experimental animal, is simple tooperate, and does not affect omnibearing examination of the head, the body and the like of the animal.

Description

technical field [0001] The invention relates to the technical field of magnetic resonance imaging equipment, in particular to an animal magnetic resonance imaging eye protection device and a use method. Background technique [0002] Magnetic Resonance Imaging (MRI) has been widely used in preclinical research and medical diagnosis. Animals are widely used in imaging experiments as a model animal in preclinical research. The premise of MRI imaging is that there is no macroscopic movement or stillness of the inspected part. The biggest difference between animal MRI and human MRI is that animals will not cooperate with inspectors or experimenters and keep a fixed position. Therefore, animal magnetic resonance imaging experiments generally first inject anesthesia drugs or continuously inhale anesthesia gas mixed with oxygen through an anesthesia device, and the animals undergo a series of imaging scans under deep anesthesia. Two hours, or even longer. [0003] The anesthetics...

AI Technical Summary

Problems solved by technology

However, in order to observe the occurrence and development of the disease, the modeling process of model animals requires repeated MRI scans at different time points. If the animal's eyes are sick or blind, it will affect the animal's diet, mood, etc., which is not conducive to specific conditions. Successful establishment of disease models and further long-term follow-up studies

[0004] Animals should take measures to protect their eyes during the MRI process, but the animals are in the center of a strong magnetic field, which is not conducive to the use of conventional protective measures

If you wait for one inspection to be completed, exit the scanning bed, apply protective measures, and then proceed to the next scan, the entry and exit of the scanning table need to be repositioned, which not only affects the experimental process, but also makes it difficult to ensure the layer position and direction of the same inspection site before and after the animal. Consistent, not conducive to later image comparison

[0005] At present, the risk of blindness in the eyes of animals is basically not considered or measures are taken when performing magnetic resonance imaging experiments on animals, but the protective measures are complicated and cover the entire head area, which is not conducive to head-related inspections

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