Tumor real-time positioning method

Abstract

The invention provides a tumor real-time positioning method, and belongs to the technical field of radiotherapy positioning. The tumor real-time positioning method comprises the steps of step S10, demarcating magnetic sensors of a magnetic sensor array; step S20, measuring magnetic induction strength data of each demarcated magnetic sensor, acted by each permanent magnet; and step S30, based on the magnetic induction strength data, establishing an error target function by using a Biot-savart's law; step S50, through an optimization algorithm, finding out the smallest positioning data of the error target function; step S50, based on the positioning data, calculating the mass center and the radius of tumors; and step S60, positioning tumors by a computer according to the position and the size, and further controlling a radiotherapy robot to clamp a linear accelerator so as to realize pinpoint chemotherapy on the tumors. The tumor real-time positioning method has the advantages that real-time positioning of the tumors can be realized, the positioning speed and precision can be greatly increased, and radiation can be reduced.

Description

technical field [0001] The invention relates to the technical field of radiotherapy positioning, in particular to a real-time tumor positioning method. Background technique [0002] Lung cancer is the main cause of human cancer death, and the effective means to improve the cure rate of lung cancer is early diagnosis and early treatment. Consequently, more than 60% of lung cancer patients require radiation therapy at various stages of the disease. However, during the radiotherapy of lung tumors, human breathing will cause the dynamic displacement of the tumor, thus affecting the curative effect of radiotherapy. [0003] Yu et al. calculated through a theoretical model that in radiation therapy, the dose deviation caused by breathing motion can reach 100%. Erridge et al. used an imaging system to study the range of motion of lung tumors in lung cancer patients. The study showed that the tumors moved from 5.2mm to 19.8mm in the direction of the head and feet, and from 4.6mm t...

AI Technical Summary

Problems solved by technology

[0005] Method 1: Place three miniature wireless alternating electromagnetic coils around the tumor to be treated. The alternating electromagnetic coils are excited by an external alternating magnetic field for a few seconds and then stop the excitation. After the miniature wireless alternating electromagnetic coils in the body are excited, they emit alternating electromagnetic coils to the outside. Signal, the external electromagnetic receiving coil array receives the signal forwarded by the wireless alternating electromagnetic coil and solves the algorithm to obtain the real-time pose of the three miniature wireless alternating electromagnetic coils, and then locates the tumor; but there are miniature wireless alternating electromagnetic coils in the body It is only used for excitation signal forwarding, which limits the tracking and positioning speed and accuracy of the system. The tracking speed is slow, and most electromagnetic tracking devices are connected by wires, which poses potential electrical safety hazards.

[0006] Method 2: Implant gold labels around the tumor, and use X-ray imaging equipment to obtain the position coordinates of the tumor target area; this method has the following disadvantages: the normal tissue around the tumor will be damaged due to long-term exposure to X-rays

[0007] Method 3: Based on the tumor-magnetic nanoparticle (MNP) method, a sensor array composed of five sensors is used to obtain the generated acoustic signal, and the acoustic signal is used to locate the tumor, which has the disadvantage that the acoustic signal tracking is easily affected by environmental noise

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